AAPS J Volume 9(3); September 2007

Volume 9(3); September 2007

Articles

Biomarkers, metabonomics, and drug development: Can inborn errors of metabolism help in understanding drug toxicity?

Subrahmanyam Vangala, Alfred Tonelli

AAPS J. 2007 September; 9(3): E284–E297. Published online 2007 July 20. doi: 10.1208/aapsj0903031

PMCID:: PMC2751476

Abstract Full Text PDF–603K

Inactivation of hepatic enzymes by inhalant nitrite—In vivo and in vitro studies

Steven G. Turowski, Kate E. Jank, Ho-Leung Fung

AAPS J. 2007 September; 9(3): E298–E305. Published online 2007 July 27. doi: 10.1208/aapsj0903032

PMCID:: PMC2751477

Abstract Full Text PDF–777K

Intellectual property policy in the pharmaceutical sciences: The effect of inappropriate patents and market exclusivity extensions on the health care system

Aaron S. Kesselheim

AAPS J. 2007 September; 9(3): E306–E311. Published online 2007 August 3. doi: 10.1208/aapsj0903033

PMCID:: PMC2751478

Abstract Full Text PDF–588K

The influence of market exclusivity on drug availability and medical innovations

Gregory J. Glover

AAPS J. 2007 September; 9(3): E312–E316. Published online 2007 August 3. doi: 10.1208/aapsj0903034

PMCID:: PMC2751479

Abstract Full Text PDF–545K

Basic of US patents and the patent system

George Elliott

AAPS J. 2007 September; 9(3): E317–E324. Published online 2007 August 24. doi: 10.1208/aapsj0903035

PMCID:: PMC2751480

Abstract Full Text PDF–569K

Fish pharmacokinetics database updated

AAPS J. 2007 September; 9(3): E325. Published online 2007 August 31. doi: 10.1208/aapsj0903036

PMCID:: PMC2751481

Abstract PDF–486K

Polyoxyethylene 40 stearate modulates multidrug resistance and enhances antitumor activity of vinblastine sulfate

Lingying Luo, Xiaoqiang Xu, Beijia Shi, Jinhui Wu, Yiqiao Hu

AAPS J. 2007 September; 9(3): E329–E335. Published online 2007 October 5. doi: 10.1208/aapsj0903039

PMCID:: PMC2751484

Abstract Full Text PDF–492K

Confirmatory reanalysis of incurred bioanalytical samples

Mario L. Rocci, Viswanath Devanarayan, David B. Haughey, Paula Jardieu

AAPS J. 2007 September; 9(3): E336–E343. Published online 2007 October 5. doi: 10.1208/aapsj0903040

PMCID:: PMC2751485

Abstract Full Text PDF–527K

Preparation and in vivo evaluation of SMEDDS (self-microemulsifying drug delivery system) containing fenofibrate

Ashok R. Patel, Pradeep R. Vavia

AAPS J. 2007 September; 9(3): E344–E352. Published online 2007 October 26. doi: 10.1208/aapsj0903041

PMCID:: PMC2751486

Abstract Full Text PDF–521K

Determination of carryover and contamination for mass spectrometry-based chromatographic assays

Nicola C. Hughes, Ernest Y. K. Wong, Juan Fan, Navgeet Bajaj

AAPS J. 2007 September; 9(3): E353–E360. Published online 2007 November 2. doi: 10.1208/aapsj0903042

PMCID:: PMC2751487

Abstract Full Text PDF–600K

Characterization of the distribution, polymorphism, and stability of nimodipine in its solid dispersions in polyethylene glycol by micro-Raman spectroscopy and powder x-ray diffraction

Aristides Docoslis, Krista L. Huszarik, George Z. Papageorgiou, Dimitrios Bikiaris, Anagnostis Stergiou, Emmanouel Georgarakis

AAPS J. 2007 September; 9(3): E361–E370. Published online 2007 December 7. doi: 10.1208/aapsj0903043

PMCID:: PMC2751488

Abstract Full Text PDF–697K

Preparation and ocular pharmacokinetics of ganciclovir liposomes

Yan Shen, Jiasheng Tu

AAPS J. 2007 September; 9(3): E371–E377. Published online 2007 December 7. doi: 10.1208/aapsj0903044

PMCID:: PMC2751489

Abstract Full Text PDF–504K

Pharmacokinetics in mice implanted with xenografted tumors after intravenous administration of tasidotin (ILX651) or its carboxylate metabolite

Peter L. Bonate, David Beyerlein, Jennifer Crawford, Stephanie Roth, Roy Krumbholz, Steve Schmid

AAPS J. 2007 September; 9(3): E378–E387. Published online 2007 December 14. doi: 10.1208/aapsj0903045

PMCID:: PMC2751490

Abstract Full Text PDF–538K

Errata

Corrigendum: Population pharmacokinetics of S(-)-carvedilol in healthy volunteers after administration of the immediate-release (IR) and the new controlled-release (CR) dosage forms of the racemate

Ahmed A. Othman, David M. Tenero, Duane A. Boyle, Natalie D. Eddington, Michael J. Fossler

AAPS J. 2007 September; 9(3): E326–E327. Published online 2007 September 28. doi: 10.1208/aapsj0903037c

Corrects:: AAPS J. 2007 June; 9(2): E208–E218.

PMCID:: PMC2751482

Correction PDF–527K Original Article

Corrigendum: 2007 highlights of advances in the pharmaceutical sciences: An American Association of Pharmaceutical Scientists (AAPS) perspective

Marilyn N. Martinez, Peter Bonate, Robert L. Chapman, Anne De Groot, Susan D'Souza, Naushad Ghilazi, Vivian Gray, Vishal K. Gupta, Kim Huynh-Ba, Sunil Iyer, Arya Jayatilaka, Amita Joshi, H. Thomas Karnes, Mansoor Khan, Patrick Liu, Craig Lunte, Christopher R. McCurdy, Marilyn E. Morris, Kenneth J. Norris, Phillip Ramsey, Sanjay Sehgal, Manuel Zahn

AAPS J. 2007 September; 9(3): E328. Published online 2007 September 28. doi: 10.1208/aapsj0903038c

Corrects:: AAPS J. 2007 June; 9(2): E219–E226.

PMCID:: PMC2751483

Correction PDF–484K Original Article

Articles from The AAPS Journal are provided here courtesy of
American Association of Pharmaceutical Scientists

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