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Volume 10(5);  2008
Commentary
Are biologics more effective than classical disease-modifying antirheumatic drugs?
Michael T Nurmohamed, Ben AC Dijkmans
Arthritis Res Ther. 2008; 10(5): 118. Published online 2008 September 19. doi: 10.1186/ar2491
PMCID:
PMC2592779
Abstract Full Text PDF–48K
Editorials
Lipooxygenase inhibition in osteoarthritis: a potential symptomatic and disease modifying effect?
Maxime Dougados
Arthritis Res Ther. 2008; 10(5): 116. Published online 2008 September 19. doi: 10.1186/ar2490
PMCID:
PMC2592778
Abstract Full Text PDF–41K
An important step towards completing the rheumatoid arthritis cycle
Walther J van Venrooij, Ger JM Pruijn
Arthritis Res Ther. 2008; 10(5): 117. Published online 2008 September 19. doi: 10.1186/ar2504
PMCID:
PMC2592789
Abstract Full Text PDF–145K
Introducing Arthritis Research & Therapy's 10th anniversary issue, 'The Scientific Basis of Rheumatology: A Decade of Progress'
Iain Hrynaszkiewicz, Peter E Lipsky, Ravinder N Maini
Arthritis Res Ther. 2008; 10(5): 119. Published online 2008 October 10. doi: 10.1186/ar2522
PMCID:
PMC2592806
Full Text PDF–99K
Serum urate, menopause, and postmenopausal hormone use: from eminence to evidence-based medicine
Angelo L Gaffo, Kenneth G Saag
Arthritis Res Ther. 2008; 10(5): 120. Published online 2008 October 17. doi: 10.1186/ar2524
PMCID:
PMC2592808
Abstract Full Text PDF–39K
High-density lipoprotein: does it have a dark side?
Joan M Von Feldt
Arthritis Res Ther. 2008; 10(5): 121. Published online 2008 October 31. doi: 10.1186/ar2527
PMCID:
PMC2592810
Abstract Full Text PDF–39K
Research Articles
A polymorphism in the human serotonin 5-HT2A receptor gene may protect against systemic sclerosis by reducing platelet aggregation
Lorenzo Beretta, Marta Cossu, Maurizio Marchini, Francesca Cappiello, Andrea Artoni, Giovanna Motta, Raffaella Scorza
Arthritis Res Ther. 2008; 10(5): R103. Published online 2008 September 1. doi: 10.1186/ar2495
PMCID:
PMC2592780
Abstract Full Text PDF–202K
The relationship between inflammation and new bone formation in patients with ankylosing spondylitis
Xenofon Baraliakos, Joachim Listing, Martin Rudwaleit, Joachim Sieper, Juergen Braun
Arthritis Res Ther. 2008; 10(5): R104. Published online 2008 September 1. doi: 10.1186/ar2496
PMCID:
PMC2592781
Abstract Full Text PDF–217K
Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab
Sanna Rosengren, Nathan Wei, Kenneth C Kalunian, Nathan J Zvaifler, Arthur Kavanaugh, David L Boyle
Arthritis Res Ther. 2008; 10(5): R105. Published online 2008 September 1. doi: 10.1186/ar2497
PMCID:
PMC2592782
Abstract Full Text PDF–488K
Prognostic factors of 10-year radiographic outcome in early rheumatoid arthritis: a prospective study
Natacha Courvoisier, Maxime Dougados, Alain Cantagrel, Philippe Goupille, Olivier Meyer, Jean Sibilia, Jean Pierre Daures, Bernard Combe
Arthritis Res Ther. 2008; 10(5): R106. Published online 2008 September 4. doi: 10.1186/ar2498
PMCID:
PMC2592783
Abstract Full Text PDF–172K
4-Hydroxynonenal induces apoptosis in human osteoarthritic chondrocytes: the protective role of glutathione-S-transferase
France Vaillancourt, Hassan Fahmi, Qin Shi, Patrick Lavigne, Pierre Ranger, Julio C Fernandes, Mohamed Benderdour
Arthritis Res Ther. 2008; 10(5): R107. Published online 2008 September 9. doi: 10.1186/ar2503
PMCID:
PMC2592788
Abstract Full Text PDF–1.5M
Reduced proportions of natural killer T cells are present in the relatives of lupus patients and are associated with autoimmunity
Joan Wither, Yong-chun Cai, Sooyeol Lim, Tamara McKenzie, Nicole Roslin, Jaime O Claudio, Glinda S Cooper, Thomas J Hudson, Andrew D Paterson, Celia MT Greenwood, Dafna Gladman, Janet Pope, Christian A Pineau, C Douglas Smith, John G Hanly, Christine Peschken, Gilles Boire, CaNIOS Investigators, Paul R Fortin
Arthritis Res Ther. 2008; 10(5): R108. Published online 2008 September 10. doi: 10.1186/ar2505
PMCID:
PMC2592790
Abstract Full Text PDF–542K
Biologic activity and safety of belimumab, a neutralizing anti-B-lymphocyte stimulator (BLyS) monoclonal antibody: a phase I trial in patients with systemic lupus erythematosus
Richard Furie, William Stohl, Ellen M Ginzler, Michael Becker, Nilamadhab Mishra, Winn Chatham, Joan T Merrill, Arthur Weinstein, W Joseph McCune, John Zhong, Wendy Cai, William Freimuth, the Belimumab Study Group
Arthritis Res Ther. 2008; 10(5): R109. Published online 2008 September 11. doi: 10.1186/ar2506
PMCID:
PMC2592791
Abstract Full Text PDF–847K
Natural autoantibodies reactive with glycosaminoglycans in rheumatoid arthritis
Bence György, László Tóthfalusi, György Nagy, Mária Pásztói, Pál Géher, Zsolt Lörinc, Anna Polgár, Bernadett Rojkovich, Ilona Ujfalussy, Gyula Poór, Péter Pócza, Zoltán Wiener, Petra Misják, Agnes Koncz, András Falus, Edit I Buzás
Arthritis Res Ther. 2008; 10(5): R110. Published online 2008 September 12. doi: 10.1186/ar2507
PMCID:
PMC2592792
Abstract Full Text PDF–1.4M
Role of hypoxia-inducible factor 1alpha in the integrity of articular cartilage in murine knee joints
Kolja Gelse, David Pfander, Simon Obier, Karl X Knaup, Michael Wiesener, Friedrich F Hennig, Bernd Swoboda
Arthritis Res Ther. 2008; 10(5): R111. Published online 2008 September 12. doi: 10.1186/ar2508
PMCID:
PMC2592793
Abstract Full Text PDF–3.5M
Association of elevated transcript levels of interferon-inducible chemokines with disease activity and organ damage in systemic lupus erythematosus patients
Qiong Fu, Xiaoqing Chen, Huijuan Cui, Yanzhi Guo, Jing Chen, Nan Shen, Chunde Bao
Arthritis Res Ther. 2008; 10(5): R112. Published online 2008 September 15. doi: 10.1186/ar2510
PMCID:
PMC2592795
Abstract Full Text PDF–411K
Role of STAT4 polymorphisms in systemic lupus erythematosus in a Japanese population: a case-control association study of the STAT1-STAT4 region
Aya Kawasaki, Ikue Ito, Koki Hikami, Jun Ohashi, Taichi Hayashi, Daisuke Goto, Isao Matsumoto, Satoshi Ito, Akito Tsutsumi, Minori Koga, Tadao Arinami, Robert R Graham, Geoffrey Hom, Yoshinari Takasaki, Hiroshi Hashimoto, Timothy W Behrens, Takayuki Sumida, Naoyuki Tsuchiya
Arthritis Res Ther. 2008; 10(5): R113. Published online 2008 September 19. doi: 10.1186/ar2516
PMCID:
PMC2592800
Abstract Full Text PDF–224K
Myeloid dendritic cells display downregulation of C-type lectin receptors and aberrant lectin uptake in systemic lupus erythematosus
Seetha U Monrad, Kristine Rea, Seth Thacker, Mariana J Kaplan
Arthritis Res Ther. 2008; 10(5): R114. Published online 2008 September 23. doi: 10.1186/ar2517
PMCID:
PMC2592801
Abstract Full Text PDF–566K
Dynamic activation of bone morphogenetic protein signaling in collagen-induced arthritis supports their role in joint homeostasis and disease
Melina Daans, Rik JU Lories, Frank P Luyten
Arthritis Res Ther. 2008; 10(5): R115. Published online 2008 September 24. doi: 10.1186/ar2518
PMCID:
PMC2592802
Abstract Full Text PDF–2.0M
Menopause, postmenopausal hormone use and serum uric acid levels in US women – The Third National Health and Nutrition Examination Survey
A Elisabeth Hak, Hyon K Choi
Arthritis Res Ther. 2008; 10(5): R116. Published online 2008 September 26. doi: 10.1186/ar2519
PMCID:
PMC2592803
Abstract Full Text PDF–125K
Decreased levels of the gelsolin plasma isoform in patients with rheumatoid arthritis
Teresia M Osborn, Margareta Verdrengh, Thomas P Stossel, Andrej Tarkowski, Maria Bokarewa
Arthritis Res Ther. 2008; 10(5): R117. Published online 2008 September 27. doi: 10.1186/ar2520
PMCID:
PMC2592804
Abstract Full Text PDF–705K
Weekly intra-articular injections of bone morphogenetic protein-7 inhibits osteoarthritis progression
Masaya Hayashi, Takeshi Muneta, Young-Jin Ju, Tomoyuki Mochizuki, Ichiro Sekiya
Arthritis Res Ther. 2008; 10(5): R118. Published online 2008 September 30. doi: 10.1186/ar2521
PMCID:
PMC2592805
Abstract Full Text PDF–2.4M
Epitope spreading to citrullinated antigens in mouse models of autoimmune arthritis and demyelination
Brian A Kidd, Peggy P Ho, Orr Sharpe, Xiaoyan Zhao, Beren H Tomooka, Jennifer L Kanter, Lawrence Steinman, William H Robinson
Arthritis Res Ther. 2008; 10(5): R119. Published online 2008 September 30. doi: 10.1186/ar2523
PMCID:
PMC2592807
Abstract Full Text PDF–2.3M Supplementary Material
Rationale for prostaglandin I2 in bone marrow oedema – from theory to application
Marcus Jäger, Frank Peter Tillmann, Thomas S Thornhill, Marcus Mahmoudi, Dirk Blondin, Gerd Rüdiger Hetzel, Christoph Zilkens, Rüdiger Krauspe
Arthritis Res Ther. 2008; 10(5): R120. Published online 2008 October 3. doi: 10.1186/ar2526
PMCID:
PMC2592809
Abstract Full Text PDF–1.1M
Toll-like receptor homolog RP105 modulates the antigen-presenting cell function and regulates the development of collagen-induced arthritis
Yoshifumi Tada, Syuichi Koarada, Fumitaka Morito, Mio Mitamura, Hisako Inoue, Rie Suematsu, Akihide Ohta, Kensuke Miyake, Kohei Nagasawa
Arthritis Res Ther. 2008; 10(5): R121. Published online 2008 October 11. doi: 10.1186/ar2529
PMCID:
PMC2592811
Abstract Full Text PDF–1.1M
Therapeutic effect of the potent IL-12/IL-23 inhibitor STA-5326 on experimental autoimmune uveoretinitis
Hiroshi Keino, Takayo Watanabe, Yasuhiko Sato, Mamoru Niikura, Yumiko Wada, Annabelle A Okada
Arthritis Res Ther. 2008; 10(5): R122. Published online 2008 October 13. doi: 10.1186/ar2530
PMCID:
PMC2592812
Abstract Full Text PDF–770K
Vitamin D deficiency in undifferentiated connective tissue disease
Eva Zold, Peter Szodoray, Janos Gaal, János Kappelmayer, Laszlo Csathy, Edit Gyimesi, Margit Zeher, Gyula Szegedi, Edit Bodolay
Arthritis Res Ther. 2008; 10(5): R123. Published online 2008 October 18. doi: 10.1186/ar2533
PMCID:
PMC2592813
Abstract Full Text PDF–233K
Serum levels of biomarkers of bone and cartilage destruction and new bone formation in different cohorts of patients with axial spondyloarthritis with and without tumor necrosis factor-alpha blocker treatment
Heiner Appel, Louise Janssen, Joachim Listing, René Heydrich, Martin Rudwaleit, Joachim Sieper
Arthritis Res Ther. 2008; 10(5): R125. Published online 2008 October 22. doi: 10.1186/ar2537
PMCID:
PMC2592815
Abstract Full Text PDF–446K
Association of a single nucleotide polymorphism in growth differentiate factor 5 with congenital dysplasia of the hip: a case-control study
Jin Dai, Dongquan Shi, Pengsheng Zhu, Jianghui Qin, Haijian Ni, Yong Xu, Chen Yao, Lunqing Zhu, Hongtao Zhu, Baocheng Zhao, Jia Wei, Baorui Liu, Shiro Ikegawa, Qing Jiang, Yitao Ding
Arthritis Res Ther. 2008; 10(5): R126. Published online 2008 October 24. doi: 10.1186/ar2540
PMCID:
PMC2592816
Abstract Full Text PDF–124K
Reviews
Genetic studies in osteoporosis – the end of the beginning
Emma L Duncan, Matthew A Brown
Arthritis Res Ther. 2008; 10(5): 214. Published online 2008 September 12. doi: 10.1186/ar2479
PMCID:
PMC2592817
Abstract Full Text PDF–272K
Virally associated arthritis 2008: clinical, epidemiologic, and pathophysiologic considerations
Dimitrios Vassilopoulos, Leonard H Calabrese
Arthritis Res Ther. 2008; 10(5): 215. Published online 2008 September 18. doi: 10.1186/ar2480
PMCID:
PMC2592818
Abstract Full Text PDF–72K
Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis
Stefan K Drexler, Philip L Kong, Jeremy Wales, Brian M Foxwell
Arthritis Res Ther. 2008; 10(5): 216. Published online 2008 October 10. doi: 10.1186/ar2481
PMCID:
PMC2592774
Abstract Full Text PDF–603K
Stem cell transplantation for rheumatic autoimmune diseases
Thomas Hügle, Jacob M van Laar
Arthritis Res Ther. 2008; 10(5): 217. Published online 2008 October 10. doi: 10.1186/ar2486
PMCID:
PMC2592775
Abstract Full Text PDF–827K
Developments in the scientific understanding of lupus
Stacy P Ardoin, David S Pisetsky
Arthritis Res Ther. 2008; 10(5): 218. Published online 2008 October 10. doi: 10.1186/ar2488
PMCID:
PMC2592776
Abstract Full Text PDF–216K
Epigenetic modifications in rheumatoid arthritis
Simon Strietholt, Britta Maurer, Marvin A Peters, Thomas Pap, Steffen Gay
Arthritis Res Ther. 2008; 10(5): 219. Published online 2008 October 10. doi: 10.1186/ar2500
PMCID:
PMC2592785
Abstract Full Text PDF–598K
Developments in the scientific and clinical understanding of inflammatory myopathies
Ingrid E Lundberg, Cecilia Grundtman
Arthritis Res Ther. 2008; 10(5): 220. Published online 2008 October 10. doi: 10.1186/ar2501
PMCID:
PMC2592786
Abstract Full Text PDF–942K
Developments in the scientific and clinical understanding of gout
Alexander So
Arthritis Res Ther. 2008; 10(5): 221. Published online 2008 October 10. doi: 10.1186/ar2509
PMCID:
PMC2592794
Abstract Full Text PDF–426K
What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis – the first 50 years
Dennis McGonagle, Ai Lyn Tan
Arthritis Res Ther. 2008; 10(5): 222. Published online 2008 October 10. doi: 10.1186/ar2512
Correction in:
Arthritis Res Ther. 2009; 11(1): 401.
PMCID:
PMC2592796
Abstract Full Text PDF–512K Correction
Mesenchymal stem cells in arthritic diseases
Faye H Chen, Rocky S Tuan
Arthritis Res Ther. 2008; 10(5): 223. Published online 2008 October 10. doi: 10.1186/ar2514
PMCID:
PMC2592798
Abstract Full Text PDF–1.0M
Vascular involvement in rheumatic diseases: 'vascular rheumatology'
Zoltán Szekanecz, Alisa E Koch
Arthritis Res Ther. 2008; 10(5): 224. Published online 2008 October 10. doi: 10.1186/ar2515
PMCID:
PMC2592799
Abstract Full Text PDF–138K
Immune regulation of bone loss by Th17 cells
Iannis E Adamopoulos, Edward P Bowman
Arthritis Res Ther. 2008; 10(5): 225. Published online 2008 October 17. doi: 10.1186/ar2502
PMCID:
PMC2592787
Abstract Full Text PDF–335K
Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?
Aleksander M Grabiec, Paul P Tak, Kris A Reedquist
Arthritis Res Ther. 2008; 10(5): 226. Published online 2008 October 17. doi: 10.1186/ar2489
PMCID:
PMC2592777
Abstract Full Text PDF–921K Supplementary Material
Corrections
Correction: Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
Thomas Dörner, Joerg Kaufmann, William A Wegener, Nick Teoh, David M Goldenberg, Gerd R Burmester
Arthritis Res Ther. 2008; 10(5): 406. Published online 2008 September 9. doi: 10.1186/ar2499
Corrects:
Arthritis Res Ther. 2006; 8(3): R74.
PMCID:
PMC2592784
Correction PDF–32K Original Article
Correction: Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis
C Thomas G Appleton, David D McErlain, Vasek Pitelka, Neil Schwartz, Suzanne M Bernier, James L Henry, David W Holdsworth, Frank Beier
Arthritis Res Ther. 2008; 10(5): 407. Published online 2008 September 22. doi: 10.1186/ar2513
Corrects:
Arthritis Res Ther. 2007; 9(1): R13.
PMCID:
PMC2592797
Correction PDF–31K Original Article
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