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Volume 44(12);  December 2000
Minireview
Aminoglycosides: Perspectives on Mechanisms of Action and Resistance and Strategies to Counter Resistance
Lakshmi P. Kotra, Jalal Haddad, Shahriar Mobashery
Antimicrob Agents Chemother. 2000 December; 44(12): 3249–3256.
PMCID:
PMC90188
Full Text PDF–2.5M
Mechanisms of Action: Physiological Effects
Candidacidal Activities of Human Lactoferrin Peptides Derived from the N Terminus
Antonella Lupetti, Akke Paulusma-Annema, Mick M. Welling, Sonia Senesi, Jaap T. van Dissel, Peter H. Nibbering
Antimicrob Agents Chemother. 2000 December; 44(12): 3257–3263.
PMCID:
PMC90189
Abstract Full Text PDF–303K
Salivary Histatin 5 and Human Neutrophil Defensin 1 Kill Candida albicans via Shared Pathways
Mira Edgerton, Svetlana E. Koshlukova, Marcelo W. B. Araujo, Rashmi C. Patel, Jin Dong, Jeremy A. Bruenn
Antimicrob Agents Chemother. 2000 December; 44(12): 3310–3316.
PMCID:
PMC90198
Abstract Full Text PDF–275K
Interactions of Bacterial Cationic Peptide Antibiotics with Outer and Cytoplasmic Membranes of Pseudomonas aeruginosa
Lijuan Zhang, Pawandeep Dhillon, Hong Yan, Susan Farmer, Robert E. W. Hancock
Antimicrob Agents Chemother. 2000 December; 44(12): 3317–3321.
PMCID:
PMC90199
Abstract Full Text PDF–102K
Effect of Subinhibitory Antibiotic Concentrations on Polysaccharide Intercellular Adhesin Expression in Biofilm-Forming Staphylococcus epidermidis
Shwan Rachid, Knut Ohlsen, Wolfgang Witte, Jörg Hacker, Wilma Ziebuhr
Antimicrob Agents Chemother. 2000 December; 44(12): 3357–3363.
PMCID:
PMC90205
Abstract Full Text PDF–198K
Presence of Variations in Ribosomal Protein L16 Corresponding to Susceptibility of Enterococci to Oligosaccharides (Avilamycin and Evernimicin)
Frank Møller Aarestrup, Lars Bogø Jensen
Antimicrob Agents Chemother. 2000 December; 44(12): 3425–3427.
PMCID:
PMC90215
Abstract Full Text PDF–70K
Mechanisms of Resistance
Characterization of Spontaneous, In Vitro-Selected, Rifampin-Resistant Mutants of Mycobacterium tuberculosis Strain H37Rv
Glenn P. Morlock, Bonnie B. Plikaytis, Jack T. Crawford
Antimicrob Agents Chemother. 2000 December; 44(12): 3298–3301.
PMCID:
PMC90195
Abstract Full Text PDF–54K
Substrate Specificities of MexAB-OprM, MexCD-OprJ, and MexXY-OprM Efflux Pumps in Pseudomonas aeruginosa
Nobuhisa Masuda, Eiko Sakagawa, Satoshi Ohya, Naomasa Gotoh, Hideto Tsujimoto, Takeshi Nishino
Antimicrob Agents Chemother. 2000 December; 44(12): 3322–3327.
PMCID:
PMC90200
Abstract Full Text PDF–146K
Mutant Prevention Concentration as a Measure of Fluoroquinolone Potency against Mycobacteria
Georg Sindelar, Xilin Zhao, Anthony Liew, Yuzhi Dong, Tao Lu, Jianfeng Zhou, John Domagala, Karl Drlica
Antimicrob Agents Chemother. 2000 December; 44(12): 3337–3343.
PMCID:
PMC90202
Abstract Full Text PDF–114K
Mechanisms and Frequency of Resistance to Premafloxacin in Staphylococcus aureus: Novel Mutations Suggest Novel Drug-Target Interactions
Dilek Ince, David C. Hooper
Antimicrob Agents Chemother. 2000 December; 44(12): 3344–3350.
PMCID:
PMC90203
Abstract Full Text PDF–86K
Characterization of an In Vitro-Selected Amoxicillin-Resistant Strain of Helicobacter pylori
Cindy R. DeLoney, Neal L. Schiller
Antimicrob Agents Chemother. 2000 December; 44(12): 3368–3373.
PMCID:
PMC90207
Abstract Full Text PDF–208K
Two New Mechanisms of Macrolide Resistance in Clinical Strains of Streptococcus pneumoniae from Eastern Europe and North America
A. Tait-Kamradt, T. Davies, P. C. Appelbaum, F. Depardieu, P. Courvalin, J. Petitpas, L. Wondrack, A. Walker, M. R. Jacobs, J. Sutcliffe
Antimicrob Agents Chemother. 2000 December; 44(12): 3395–3401.
PMCID:
PMC90211
Abstract Full Text PDF–329K
High-Level Fluoroquinolone-Resistant Clinical Isolates of Escherichia coli Overproduce Multidrug Efflux Protein AcrA
Annarita Mazzariol, Yutaka Tokue, Tiffany M. Kanegawa, Giuseppe Cornaglia, Hiroshi Nikaido
Antimicrob Agents Chemother. 2000 December; 44(12): 3441–3443.
Correction in:
Antimicrob Agents Chemother. 2001 February; 45(2): 647.
PMCID:
PMC90220
Abstract Full Text PDF–60K Correction
Characterization of a Divergent vanD-Type Resistance Element from the First Glycopeptide-Resistant Strain of Enterococcus faecium Isolated in Brazil
Libera M. Dalla Costa, Peter E. Reynolds, Helena A. P. H. M. Souza, Dilair C. Souza, Marie-France I. Palepou, Neil Woodford
Antimicrob Agents Chemother. 2000 December; 44(12): 3444–3446.
PMCID:
PMC90221
Abstract Full Text PDF–84K
Structural and Topological Differences between a Glycopeptide-Intermediate Clinical Strain and Glycopeptide-Susceptible Strains of Staphylococcus aureus Revealed by Atomic Force Microscopy
Susan Boyle-Vavra, Jongin Hahm, S. J. Sibener, Robert S. Daum
Antimicrob Agents Chemother. 2000 December; 44(12): 3456–3460.
PMCID:
PMC90224
Abstract Full Text PDF–2.1M
Use of Molecular Beacons To Detect an Antifolate Resistance-Associated Mutation in Plasmodium falciparum
Rémy Durand, Jobin Eslahpazire, Sayeh Jafari, Jean-François Delabre, Anne Marmorat-Khuong, Jean-Philippe di Piazza, Jacques Le Bras
Antimicrob Agents Chemother. 2000 December; 44(12): 3461–3464.
PMCID:
PMC90225
Abstract Full Text PDF–68K
Susceptibility
In Vitro and In Vivo Activities of LB 10827, a New Oral Cephalosporin, against Respiratory Pathogens
Kyong-Sook Paek, Mu-Yong Kim, Chang-Seok Lee, Hasik Youn
Antimicrob Agents Chemother. 2000 December; 44(12): 3272–3277.
PMCID:
PMC90191
Abstract Full Text PDF–140K
Influence of Human Sera on the In Vitro Activity of the Echinocandin Caspofungin (MK-0991) against Aspergillus fumigatus
Tom Chiller, Kouros Farrokhshad, Elmer Brummer, David A. Stevens
Antimicrob Agents Chemother. 2000 December; 44(12): 3302–3305.
PMCID:
PMC90196
Abstract Full Text PDF–85K
Antibacterial Spectrum of a Novel Des-Fluoro(6) Quinolone, BMS-284756
Joan C. Fung-Tomc, Beatrice Minassian, Benjamin Kolek, Elizabeth Huczko, Lauren Aleksunes, Terry Stickle, Thomas Washo, Elizabeth Gradelski, Lourdes Valera, Daniel P. Bonner
Antimicrob Agents Chemother. 2000 December; 44(12): 3351–3356.
PMCID:
PMC90204
Abstract Full Text PDF–76K
Quinupristin-Dalfopristin Resistance among Gram-Positive Bacteria in Taiwan
Kwen-Tay Luh, Po-Ren Hsueh, Lee-Jene Teng, Hui-Ju Pan, Yu-Chi Chen, Jang-Jih Lu, Jiunn-Jong Wu, Shen-Wu Ho
Antimicrob Agents Chemother. 2000 December; 44(12): 3374–3380.
PMCID:
PMC90208
Abstract Full Text PDF–79K
Bactericidal Activities of Antibiotics against Intracellular Francisella tularensis
M. Maurin, N. F. Mersali, D. Raoult
Antimicrob Agents Chemother. 2000 December; 44(12): 3428–3431.
PMCID:
PMC90216
Abstract Full Text PDF–69K
Comparative In Vitro Activities of Daptomycin and Vancomycin against Resistant Gram-Positive Pathogens
D. R. Snydman, N. V. Jacobus, L. A. McDermott, J. R. Lonks, J. M. Boyce
Antimicrob Agents Chemother. 2000 December; 44(12): 3447–3450.
PMCID:
PMC90222
Abstract Full Text PDF–65K
Short-Term Exposure to Membrane-Active Antibiotics Inhibits Cryptosporidium parvum Infection in Cell Culture
Andrea Giacometti, Oscar Cirioni, Maria Simona Del Prete, Francesco Barchiesi, Giorgio Scalise
Antimicrob Agents Chemother. 2000 December; 44(12): 3473–3475.
PMCID:
PMC90227
Abstract Full Text PDF–40K
Susceptibilities of Corynebacterium bovis and Corynebacterium amylocolatum Isolates from Bovine Mammary Glands to 15 Antimicrobial Agents
Jeffrey L. Watts, Silvia Rossbach
Antimicrob Agents Chemother. 2000 December; 44(12): 3476–3477.
PMCID:
PMC90228
Abstract Full Text PDF–43K
Biologic Response Modifiers
Antiviral Agents
Anti-Epstein-Barr Virus (EBV) Activity of β-l-5-Iododioxolane Uracil Is Dependent on EBV Thymidine Kinase
Toshihiko Kira, Susan P. Grill, Ginger E. Dutschman, Ju-Sheng Lin, Fucheng Qu, Yongseok Choi, Chung K. Chu, Yung-Chi Cheng
Antimicrob Agents Chemother. 2000 December; 44(12): 3278–3284.
PMCID:
PMC90192
Abstract Full Text PDF–181K
Antiretroviral Agents Inhibit Infection of Human Cells by Porcine Endogenous Retroviruses
S. K. Powell, M. E. Gates, G. Langford, M.-L. Gu, C. Lockey, Z. Long, E. Otto
Antimicrob Agents Chemother. 2000 December; 44(12): 3432–3433.
PMCID:
PMC90217
Abstract Full Text PDF–99K
Hepatitis B or Hepatitis C Virus Infection Is a Risk Factor for Severe Hepatic Cytolysis after Initiation of a Protease Inhibitor-Containing Antiretroviral Regimen in Human Immunodeficiency Virus-Infected Patients
Marianne Savès, François Raffi, Philippe Clevenbergh, Bruno Marchou, Anne Waldner-Combernoux, Philippe Morlat, Vincent Le Moing, Catherine Rivière, Geneviève Chêne, Catherine Leport, The APROCO Study Group
Antimicrob Agents Chemother. 2000 December; 44(12): 3451–3455.
PMCID:
PMC90223
Abstract Full Text PDF–68K
Differential Removal of Thymidine Nucleotide Analogues from Blocked DNA Chains by Human Immunodeficiency Virus Reverse Transcriptase in the Presence of Physiological Concentrations of 2′-Deoxynucleoside Triphosphates
Peter R. Meyer, Suzanne E. Matsuura, Raymond F. Schinazi, Antero G. So, Walter A. Scott
Antimicrob Agents Chemother. 2000 December; 44(12): 3465–3472.
PMCID:
PMC90226
Abstract Full Text PDF–2.8M
Experimental Therapeutics
Persistence of Chlamydia trachomatis Is Induced by Ciprofloxacin and Ofloxacin In Vitro
Ute Dreses-Werringloer, Ingrid Padubrin, Barbara Jürgens-Saathoff, Alan P. Hudson, H. Zeidler, L. Köhler
Antimicrob Agents Chemother. 2000 December; 44(12): 3288–3297.
PMCID:
PMC90194
Abstract Full Text PDF–1.4M
Polycationic Peptides as Prophylactic Agents against Methicillin-Susceptible or Methicillin-Resistant Staphylococcus epidermidis Vascular Graft Infection
Andrea Giacometti, Oscar Cirioni, Roberto Ghiselli, Luigi Goffi, Federico Mocchegiani, Alessandra Riva, Giorgio Scalise, Vittorio Saba
Antimicrob Agents Chemother. 2000 December; 44(12): 3306–3309.
PMCID:
PMC90197
Abstract Full Text PDF–67K
Photoactive Porphyrin Derivative with Broad-Spectrum Activity against Oral Pathogens In Vitro
C. R. Rovaldi, A. Pievsky, N. A. Sole, P. M. Friden, D. M. Rothstein, P. Spacciapoli
Antimicrob Agents Chemother. 2000 December; 44(12): 3364–3367.
PMCID:
PMC90206
Abstract Full Text PDF–105K
Efficacies of Two New Antifungal Agents, the Triazole Ravuconazole and the Echinocandin LY-303366, in an Experimental Model of Invasive Aspergillosis
Jenna Roberts, Kathleen Schock, Susan Marino, Vincent T. Andriole
Antimicrob Agents Chemother. 2000 December; 44(12): 3381–3388.
PMCID:
PMC90209
Abstract Full Text PDF–102K
Activities of Sordarins in Experimental Models of Candidiasis, Aspergillosis, and Pneumocystosis
Antonio Martinez, Pablo Aviles, Elena Jimenez, Jesus Caballero, Domingo Gargallo-Viola
Antimicrob Agents Chemother. 2000 December; 44(12): 3389–3394.
PMCID:
PMC90210
Abstract Full Text PDF–100K
Efficacy of Telithromycin (HMR 3647) against Enterococci in a Mouse Peritonitis Model
Kavindra V. Singh, Karen K. Zscheck, Barbara E. Murray
Antimicrob Agents Chemother. 2000 December; 44(12): 3434–3437.
PMCID:
PMC90218
Abstract Full Text PDF–71K
Linezolid Therapy of Staphylococcus aureus Experimental Osteomyelitis
Robin Patel, Kerryl E. Piper, Mark S. Rouse, James M. Steckelberg
Antimicrob Agents Chemother. 2000 December; 44(12): 3438–3440.
PMCID:
PMC90219
Abstract Full Text PDF–54K
Clinical Therapeutics
Monotherapy with Intravenous Followed by Oral High-Dose Ciprofloxacin versus Combination Therapy with Ceftazidime plus Amikacin as Initial Empiric Therapy for Granulocytopenic Patients with Fever
Helen Giamarellou, Harry P. Bassaris, George Petrikkos, Wilhelm Busch, Michel Voulgarelis, Anastasia Antoniadou, Elisabeth Grouzi, Nikolaos Zoumbos
Antimicrob Agents Chemother. 2000 December; 44(12): 3264–3271.
PMCID:
PMC90190
Abstract Full Text PDF–85K
Early Bactericidal Activity of Paromomycin (Aminosidine) in Patients with Smear-Positive Pulmonary Tuberculosis
P. R. Donald, F. A. Sirgel, T. P. Kanyok, L. H. Danziger, A. Venter, F. J. Botha, D. P. Parkin, H. I. Seifart, B. W. Van de Wal, J. S. Maritz, D. A. Mitchison
Antimicrob Agents Chemother. 2000 December; 44(12): 3285–3287.
PMCID:
PMC90193
Abstract Full Text PDF–52K
Randomized Comparison of Linezolid (PNU-100766) versus Oxacillin-Dicloxacillin for Treatment of Complicated Skin and Soft Tissue Infections
Dennis L. Stevens, Leon G. Smith, Jon B. Bruss, Maureen A. McConnell-Martin, Sue E. Duvall, Wesley Mark Todd, Barry Hafkin
Antimicrob Agents Chemother. 2000 December; 44(12): 3408–3413.
PMCID:
PMC90213
Abstract Full Text PDF–79K
Pharmacology
Mefloquine Pharmacokinetic-Pharmacodynamic Models: Implications for Dosing and Resistance
Julie A. Simpson, Emmeline R. Watkins, Ric N. Price, Leon Aarons, Dennis E. Kyle, Nicholas J. White
Antimicrob Agents Chemother. 2000 December; 44(12): 3414–3424.
PMCID:
PMC90214
Abstract Full Text PDF–166K
Levofloxacin Pharmacokinetics and Serum Bactericidal Activities against Five Enterobacterial Species
Hilte F. Geerdes-Fenge, Axel Wiedersich, S. Wagner, Karl-Heinz Lehr, Peter Koeppe, Hartmut Lode
Antimicrob Agents Chemother. 2000 December; 44(12): 3478–3480.
PMCID:
PMC90229
Abstract Full Text PDF–65K
Letters to the Editor
Influences of Different Factors on Prevalence of Ciprofloxacin Resistance in Streptococcus pneumoniae in Spain
C. García-Rey, L. Aguilar, F. Baquero, Spanish Surveillance Group for Respiratory Pathogens
Antimicrob Agents Chemother. 2000 December; 44(12): 3481–3482.
PMCID:
PMC90230
Full Text PDF–44K
Isolation of an SHV-12 β-Lactamase-Producing Escherichia coli Strain from a Dog with Recurrent Urinary Tract Infections
Tirushet Teshager, Lucas Domínguez, Miguel A. Moreno, Yolanda Saénz, Carmen Torres, Susana Cardeñosa
Antimicrob Agents Chemother. 2000 December; 44(12): 3483–3484.
Correction in:
Antimicrob Agents Chemother. 2001 January; 45(1): 373.
PMCID:
PMC90231
Full Text PDF–40K Correction
Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of
American Society for Microbiology (ASM)