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Volume 49(6);  June 2005
Minireview
New Small-Molecule Synthetic Antimycobacterials
Lluis Ballell, Robert A. Field, Ken Duncan, Robert J. Young
Antimicrob Agents Chemother. 2005 June; 49(6): 2153–2163. doi: 10.1128/AAC.49.6.2153-2163.2005
Correction in:
Antimicrob Agents Chemother. 2007 May; 51(5): 1888.
PMCID:
PMC1140552
Full Text PDF–150K Correction
Mechanisms of Action: Physiological Effects
IMP Dehydrogenase from the Protozoan Parasite Toxoplasma gondii
William J. Sullivan, Jr., Stacy E. Dixon, Catherine Li, Boris Striepen, Sherry F. Queener
Antimicrob Agents Chemother. 2005 June; 49(6): 2172–2179. doi: 10.1128/AAC.49.6.2172-2179.2005
PMCID:
PMC1140536
Abstract Full Text PDF–507K
Are Transporter Genes Other than the Chloroquine Resistance Locus (pfcrt) and Multidrug Resistance Gene (pfmdr) Associated with Antimalarial Drug Resistance?
Timothy J. C. Anderson, Shalini Nair, Huang Qin, Sittaporn Singlam, Alan Brockman, Lucy Paiphun, François Nosten
Antimicrob Agents Chemother. 2005 June; 49(6): 2180–2188. doi: 10.1128/AAC.49.6.2180-2188.2005
Correction in:
Antimicrob Agents Chemother. 2005 September; 49(9): 3990.
PMCID:
PMC1140548
Abstract Full Text PDF–280K Supplementary Material Correction
Genome-Wide Expression Profiling of the Response to Azole, Polyene, Echinocandin, and Pyrimidine Antifungal Agents in Candida albicans
Teresa T. Liu, Robin E. B. Lee, Katherine S. Barker, Richard E. Lee, Lai Wei, Ramin Homayouni, P. David Rogers
Antimicrob Agents Chemother. 2005 June; 49(6): 2226–2236. doi: 10.1128/AAC.49.6.2226-2236.2005
PMCID:
PMC1140538
Abstract Full Text PDF–761K Supplementary Material
Transcriptional Response of Enterococcus faecalis V583 to Erythromycin
Ågot Aakra, Heidi Vebø, Lars Snipen, Helmut Hirt, Are Aastveit, Vivek Kapur, Gary Dunny, Barbara Murray, Ingolf F. Nes
Antimicrob Agents Chemother. 2005 June; 49(6): 2246–2259. doi: 10.1128/AAC.49.6.2246-2259.2005
Correction in:
Antimicrob Agents Chemother. 2005 September; 49(9): 3989.
PMCID:
PMC1140525
Abstract Full Text PDF–115K Correction
Combination of Antimicrobial and Endotoxin-Neutralizing Activities of Novel Oleoylamines
Mateja Zorko, Andreja Majerle, David Šarlah, Mateja Manček Keber, Barbara Mohar, Roman Jerala
Antimicrob Agents Chemother. 2005 June; 49(6): 2307–2313. doi: 10.1128/AAC.49.6.2307-2313.2005
PMCID:
PMC1140490
Abstract Full Text PDF–165K
Divalent Metal Cations Increase the Activity of the Antimicrobial Peptide Kappacin
Stuart G. Dashper, Neil M. O'Brien-Simpson, Keith J. Cross, Rita A. Paolini, Brigitte Hoffmann, Deanne V. Catmull, Marina Malkoski, Eric C. Reynolds
Antimicrob Agents Chemother. 2005 June; 49(6): 2322–2328. doi: 10.1128/AAC.49.6.2322-2328.2005
PMCID:
PMC1140507
Abstract Full Text PDF–219K
Effect of Cell-Photosensitizer Binding and Cell Density on Microbial Photoinactivation
Tatiana N. Demidova, Michael R. Hamblin
Antimicrob Agents Chemother. 2005 June; 49(6): 2329–2335. doi: 10.1128/AAC.49.6.2329-2335.2005
PMCID:
PMC1140487
Abstract Full Text PDF–163K
Human Salivary Mucin MUC7 12-Mer-l and 12-Mer-d Peptides: Antifungal Activity in Saliva, Enhancement of Activity with Protease Inhibitor Cocktail or EDTA, and Cytotoxicity to Human Cells
Guo-Xian Wei, Libuse A. Bobek
Antimicrob Agents Chemother. 2005 June; 49(6): 2336–2342. doi: 10.1128/AAC.49.6.2336-2342.2005
PMCID:
PMC1140489
Abstract Full Text PDF–232K
Cellular Uptake and Efflux of Azithromycin, Erythromycin, Clarithromycin, Telithromycin, and Cethromycin
Martina Bosnar, Željko Kelnerić, Vesna Munić, Vesna Eraković, Michael J. Parnham
Antimicrob Agents Chemother. 2005 June; 49(6): 2372–2377. doi: 10.1128/AAC.49.6.2372-2377.2005
PMCID:
PMC1140530
Abstract Full Text PDF–101K
Proline Conformation-Dependent Antimicrobial Activity of a Proline-Rich Histone H1 N-Terminal Peptide Fragment Isolated from the Skin Mucus of Atlantic Salmon
Torben Lüders, Gunn Alice Birkemo, Jon Nissen-Meyer, Øivind Andersen, Ingolf F. Nes
Antimicrob Agents Chemother. 2005 June; 49(6): 2399–2406. doi: 10.1128/AAC.49.6.2399-2406.2005
PMCID:
PMC1140541
Abstract Full Text PDF–375K
Effects of Acyl versus Aminoacyl Conjugation on the Properties of Antimicrobial Peptides
Inna S. Radzishevsky, Shahar Rotem, Fadia Zaknoon, Leonid Gaidukov, Arie Dagan, Amram Mor
Antimicrob Agents Chemother. 2005 June; 49(6): 2412–2420. doi: 10.1128/AAC.49.6.2412-2420.2005
PMCID:
PMC1140510
Abstract Full Text PDF–159K
Antifungal Protein PAF Severely Affects the Integrity of the Plasma Membrane of Aspergillus nidulans and Induces an Apoptosis-Like Phenotype
Éva Leiter, Henrietta Szappanos, Christoph Oberparleiter, Lydia Kaiserer, László Csernoch, Tünde Pusztahelyi, Tamás Emri, István Pócsi, Willibald Salvenmoser, Florentine Marx
Antimicrob Agents Chemother. 2005 June; 49(6): 2445–2453. doi: 10.1128/AAC.49.6.2445-2453.2005
PMCID:
PMC1140496
Abstract Full Text PDF–496K
Mechanisms of Antibacterial Action of Three Monoterpenes
Domenico Trombetta, Francesco Castelli, Maria Grazia Sarpietro, Vincenza Venuti, Mariateresa Cristani, Claudia Daniele, Antonella Saija, Gabriela Mazzanti, Giuseppe Bisignano
Antimicrob Agents Chemother. 2005 June; 49(6): 2474–2478. doi: 10.1128/AAC.49.6.2474-2478.2005
PMCID:
PMC1140516
Abstract Full Text PDF–110K
Utilization of Target-Specific, Hypersensitive Strains of Saccharomyces cerevisiae To Determine the Mode of Action of Antifungal Compounds
Ed T. Buurman, Beth Andrews, April E. Blodgett, Jini S. Chavda, Norbert F. Schnell
Antimicrob Agents Chemother. 2005 June; 49(6): 2558–2560. doi: 10.1128/AAC.49.6.2558-2560.2005
PMCID:
PMC1140547
Abstract Full Text PDF–74K
Mechanisms of Resistance
Detection of rpoB Mutations Associated with Rifampin Resistance in Mycobacterium tuberculosis Using Denaturing Gradient Gel Electrophoresis
Mark T. McCammon, John S. Gillette, Derek P. Thomas, Srinivas V. Ramaswamy, Edward A. Graviss, Barry N. Kreiswirth, Jan Vijg, Teresa N. Quitugua
Antimicrob Agents Chemother. 2005 June; 49(6): 2200–2209. doi: 10.1128/AAC.49.6.2200-2209.2005
PMCID:
PMC1140537
Abstract Full Text PDF–342K
Detection by Denaturing Gradient Gel Electrophoresis of pncA Mutations Associated with Pyrazinamide Resistance in Mycobacterium tuberculosis Isolates from the United States-Mexico Border Region
Mark T. McCammon, John S. Gillette, Derek P. Thomas, Srinivas V. Ramaswamy, Ishmael I. Rosas, Edward A. Graviss, Jan Vijg, Teresa N. Quitugua
Antimicrob Agents Chemother. 2005 June; 49(6): 2210–2217. doi: 10.1128/AAC.49.6.2210-2217.2005
PMCID:
PMC1140546
Abstract Full Text PDF–175K
Phenotypic and Molecular Characterization of Mycobacterium tuberculosis Isolates Resistant to both Isoniazid and Ethambutol
Linda M. Parsons, Max Salfinger, Anne Clobridge, Jillian Dormandy, Lisa Mirabello, Valerie L. Polletta, Ahmet Sanic, Oleg Sinyavskiy, Susan C. Larsen, Jeffrey Driscoll, Genet Zickas, Harry W. Taber
Antimicrob Agents Chemother. 2005 June; 49(6): 2218–2225. doi: 10.1128/AAC.49.6.2218-2225.2005
PMCID:
PMC1140517
Abstract Full Text PDF–84K
New Mutations and Horizontal Transfer of rpoB among Rifampin-Resistant Streptococcus pneumoniae from Four Spanish Hospitals
María José Ferrándiz, Carmen Ardanuy, Josefina Liñares, José María García-Arenzana, Emilia Cercenado, Ana Fleites, Adela G. de la Campa, the Spanish Pneumococcal Infection Study Network
Antimicrob Agents Chemother. 2005 June; 49(6): 2237–2245. doi: 10.1128/AAC.49.6.2237-2245.2005
PMCID:
PMC1140543
Abstract Full Text PDF–226K
Occurrence of Hypermutable Pseudomonas aeruginosa in Cystic Fibrosis Patients Is Associated with the Oxidative Stress Caused by Chronic Lung Inflammation
Oana Ciofu, Bente Riis, Tacjana Pressler, Henrik Enghusen Poulsen, Niels Høiby
Antimicrob Agents Chemother. 2005 June; 49(6): 2276–2282. doi: 10.1128/AAC.49.6.2276-2282.2005
PMCID:
PMC1140492
Abstract Full Text PDF–94K
Inducible Clindamycin Resistance and Molecular Epidemiologic Trends of Pediatric Community-Acquired Methicillin-Resistant Staphylococcus aureus in Dallas, Texas
Susana Chavez-Bueno, Bülent Bozdogan, Kathy Katz, Karen L. Bowlware, Nancy Cushion, Dominick Cavuoti, Naveed Ahmad, George H. McCracken, Jr., Peter C. Appelbaum
Antimicrob Agents Chemother. 2005 June; 49(6): 2283–2288. doi: 10.1128/AAC.49.6.2283-2288.2005
PMCID:
PMC1140519
Abstract Full Text PDF–152K
Emergence of Macrolide-Resistant Mycoplasma pneumoniae with a 23S rRNA Gene Mutation
Miyuki Morozumi, Keiko Hasegawa, Reiko Kobayashi, Nagako Inoue, Satoshi Iwata, Haruo Kuroki, Naohisa Kawamura, Eiichi Nakayama, Takeshi Tajima, Kouichi Shimizu, Kimiko Ubukata
Antimicrob Agents Chemother. 2005 June; 49(6): 2302–2306. doi: 10.1128/AAC.49.6.2302-2306.2005
Correction in:
Antimicrob Agents Chemother. 2005 July; 49(7): 3100.
PMCID:
PMC1140515
Abstract Full Text PDF–158K Correction
Biological Cost of Single and Multiple Norfloxacin Resistance Mutations in Escherichia coli Implicated in Urinary Tract Infections
Patricia Komp Lindgren, Linda L. Marcusson, Dorthe Sandvang, Niels Frimodt-Møller, Diarmaid Hughes
Antimicrob Agents Chemother. 2005 June; 49(6): 2343–2351. doi: 10.1128/AAC.49.6.2343-2351.2005
PMCID:
PMC1140522
Abstract Full Text PDF–222K
Mosaic Structure of a Multiple-Drug-Resistant, Conjugative Plasmid from Campylobacter jejuni
Warawadee Nirdnoy, Carl J. Mason, Patricia Guerry
Antimicrob Agents Chemother. 2005 June; 49(6): 2454–2459. doi: 10.1128/AAC.49.6.2454-2459.2005
PMCID:
PMC1140535
Abstract Full Text PDF–116K
Novel Ser79Leu and Ser81Ile Substitutions in the Quinolone Resistance-Determining Regions of ParC Topoisomerase IV and GyrA DNA Gyrase Subunits from Recent Fluoroquinolone-Resistant Streptococcus pneumoniae Clinical Isolates
Nataliya Korzheva, Todd A. Davies, Raul Goldschmidt
Antimicrob Agents Chemother. 2005 June; 49(6): 2479–2486. doi: 10.1128/AAC.49.6.2479-2486.2005
PMCID:
PMC1140505
Abstract Full Text PDF–90K
DNA in Antibiotic Preparations: Absence of Intact Resistance Genes
Markus Woegerbauer, Heimo Lagler, Wolfgang Graninger, Heinz Burgmann
Antimicrob Agents Chemother. 2005 June; 49(6): 2490–2494. doi: 10.1128/AAC.49.6.2490-2494.2005
PMCID:
PMC1140494
Abstract Full Text PDF–97K
Fluoroquinolone-Resistant Streptococcus agalactiae: Epidemiology and Mechanism of Resistance
Wehbeh Wehbeh, Roberto Rojas-Diaz, Xinying Li, Noriel Mariano, Louise Grenner, Sorana Segal-Maurer, Barbara Tommasulo, Karl Drlica, Carl Urban, James J. Rahal
Antimicrob Agents Chemother. 2005 June; 49(6): 2495–2497. doi: 10.1128/AAC.49.6.2495-2497.2005
PMCID:
PMC1140524
Abstract Full Text PDF–129K
Class I Integron with a Group II Intron Detected in an Escherichia coli Strain from a Free-Range Reindeer
Marianne Sunde
Antimicrob Agents Chemother. 2005 June; 49(6): 2512–2514. doi: 10.1128/AAC.49.6.2512-2514.2005
PMCID:
PMC1140521
Abstract Full Text PDF–70K
Isolation and Expression of a Novel Molecular Class D β-Lactamase, OXA-61, from Campylobacter jejuni
David A. Alfredson, Victoria Korolik
Antimicrob Agents Chemother. 2005 June; 49(6): 2515–2518. doi: 10.1128/AAC.49.6.2515-2518.2005
PMCID:
PMC1140520
Abstract Full Text PDF–109K
Detection of qnr in Clinical Isolates of Escherichia coli from Korea
Jin-Yong Jeong, Hyun Jung Yoon, Eun Sil Kim, Yoola Lee, Sang-Ho Choi, Nam Joong Kim, Jun Hee Woo, Yang Soo Kim
Antimicrob Agents Chemother. 2005 June; 49(6): 2522–2524. doi: 10.1128/AAC.49.6.2522-2524.2005
PMCID:
PMC1140518
Abstract Full Text PDF–97K
Multicenter Study of the Mechanisms of Resistance and Clonal Relationships of Streptococcus agalactiae Isolates Resistant to Macrolides, Lincosamides, and Ketolides in Spain
J. J. Gonzalez, A. Andreu, the Spanish Group for the Study of Perinatal Infection from the Spanish Society for Clinical Microbiology and Infectious Diseases
Antimicrob Agents Chemother. 2005 June; 49(6): 2525–2527. doi: 10.1128/AAC.49.6.2525-2527.2005
PMCID:
PMC1140544
Abstract Full Text PDF–46K
Targeted Gene Disruption of the 14-α Sterol Demethylase (cyp51A) in Aspergillus fumigatus and Its Role in Azole Drug Susceptibility
E. Mellado, G. Garcia-Effron, M. J. Buitrago, L. Alcazar-Fuoli, M. Cuenca-Estrella, J. L. Rodriguez-Tudela
Antimicrob Agents Chemother. 2005 June; 49(6): 2536–2538. doi: 10.1128/AAC.49.6.2536-2538.2005
PMCID:
PMC1140498
Abstract Full Text PDF–101K
ErmB Determinants and Tn916-Like Elements in Clinical Isolates of Clostridium difficile
Patrizia Spigaglia, Valentina Carucci, Fabrizio Barbanti, Paola Mastrantonio
Antimicrob Agents Chemother. 2005 June; 49(6): 2550–2553. doi: 10.1128/AAC.49.6.2550-2553.2005
PMCID:
PMC1140533
Abstract Full Text PDF–84K
Chromosome-Borne Class A BOR-1 β-Lactamase of Bordetella bronchiseptica and Bordetella parapertussis
Marie-Frédérique Lartigue, Laurent Poirel, Nicolas Fortineau, Patrice Nordmann
Antimicrob Agents Chemother. 2005 June; 49(6): 2565–2567. doi: 10.1128/AAC.49.6.2565-2567.2005
PMCID:
PMC1140528
Abstract Full Text PDF–110K
Identification of CTX-M-14 β-Lactamase in a Salmonella enterica Serovar Enteritidis Isolate from Japan
Hidemasa Izumiya, Kadumi Mori, Masato Higashide, Kazumichi Tamura, Nobuko Takai, Kenji Hirose, Jun Terajima, Haruo Watanabe
Antimicrob Agents Chemother. 2005 June; 49(6): 2568–2570. doi: 10.1128/AAC.49.6.2568-2570.2005
PMCID:
PMC1140493
Abstract Full Text PDF–136K
Susceptibility
Inhibitory Activity of Human Immunodeficiency Virus Aspartyl Protease Inhibitors against Encephalitozoon intestinalis Evaluated by Cell Culture-Quantitative PCR Assay
Jean Menotti, Maud Santillana-Hayat, Bruno Cassinat, Claudine Sarfati, Francis Derouin, Jean-Michel Molina
Antimicrob Agents Chemother. 2005 June; 49(6): 2362–2366. doi: 10.1128/AAC.49.6.2362-2366.2005
PMCID:
PMC1140512
Abstract Full Text PDF–90K
Antimycobacterial Agents Differ with Respect to Their Bacteriostatic versus Bactericidal Activities in Relation to Time of Exposure, Mycobacterial Growth Phase, and Their Use in Combination
Irma A. J. M. Bakker-Woudenberg, Wim van Vianen, Dick van Soolingen, Henri A. Verbrugh, Michiel A. van Agtmael
Antimicrob Agents Chemother. 2005 June; 49(6): 2387–2398. doi: 10.1128/AAC.49.6.2387-2398.2005
PMCID:
PMC1140486
Abstract Full Text PDF–255K
In Vitro Activity of Telithromycin against Macrolide-Susceptible and Macrolide-Resistant Pharyngeal Isolates of Group A Streptococci in the United States
Michael Green, Coburn Allen, John Bradley, Barry Dashefsky, Janet R. Gilsdorf, Mario J. Marcon, Gordon E. Schutze, Clay Smith, Emmanuel Walter, Judith M. Martin, Kathryn A. Edwards, Karen A. Barbadora, Renee M. Rumbaugh, Ellen R. Wald
Antimicrob Agents Chemother. 2005 June; 49(6): 2487–2489. doi: 10.1128/AAC.49.6.2487-2489.2005
PMCID:
PMC1140514
Abstract Full Text PDF–44K
In Vitro and In Vivo Activities of DA-7867, a New Oxazolidinone, against Aerobic Gram-Positive Bacteria
Eun Jeong Yoon, Yeong Woo Jo, Sung Hak Choi, Tae Ho Lee, Jae Keol Rhee, Moohi Yoo, Mi Ja Shim, Eung Chil Choi
Antimicrob Agents Chemother. 2005 June; 49(6): 2498–2500. doi: 10.1128/AAC.49.6.2498-2500.2005
PMCID:
PMC1140508
Abstract Full Text PDF–100K
Biosynthesized Tea Polyphenols Inactivate Chlamydia trachomatis In Vitro
Tsutomu Yamazaki, Toshio Kishimoto, Sadashi Shiga, Kozue Sato, Toshikatsu Hagiwara, Miyuki Inoue, Nozomu Sasaki, Kazunobu Ouchi, Yukihiko Hara
Antimicrob Agents Chemother. 2005 June; 49(6): 2501–2503. doi: 10.1128/AAC.49.6.2501-2503.2005
PMCID:
PMC1140499
Abstract Full Text PDF–108K
In Vitro Activity and Killing Effect of Citropin 1.1 against Gram-Positive Pathogens Causing Skin and Soft Tissue Infections
Andrea Giacometti, Oscar Cirioni, Wojciech Kamysz, Carmela Silvestri, Maria Simona Del Prete, Alberto Licci, Giuseppina D'Amato, Jerzy Łukasiak, Giorgio Scalise
Antimicrob Agents Chemother. 2005 June; 49(6): 2507–2509. doi: 10.1128/AAC.49.6.2507-2509.2005
PMCID:
PMC1140526
Abstract Full Text PDF–54K
In Vitro Activity of Doripenem (S-4661) against Multidrug-Resistant Gram-Negative Bacilli Isolated from Patients with Cystic Fibrosis
Yunhua Chen, Elizabeth Garber, Qiuqu Zhao, Yigong Ge, Matthew A. Wikler, Koné Kaniga, Lisa Saiman
Antimicrob Agents Chemother. 2005 June; 49(6): 2510–2511. doi: 10.1128/AAC.49.6.2510-2511.2005
PMCID:
PMC1140534
Abstract Full Text PDF–44K
In Vitro Inhibitory Effects of Hinokitiol on Proliferation of Chlamydia trachomatis
Hiroaki Yamano, Tsutomu Yamazaki, Kozue Sato, Sadashi Shiga, Toshikatsu Hagiwara, Kazunobu Ouchi, Toshio Kishimoto
Antimicrob Agents Chemother. 2005 June; 49(6): 2519–2521. doi: 10.1128/AAC.49.6.2519-2521.2005
PMCID:
PMC1140513
Abstract Full Text PDF–113K
In Vitro and Intracellular Activities of LBM415 (NVP PDF-713) against Legionella pneumophila
Paul H. Edelstein, Baofeng Hu, Martha A. C. Edelstein
Antimicrob Agents Chemother. 2005 June; 49(6): 2533–2535. doi: 10.1128/AAC.49.6.2533-2535.2005
PMCID:
PMC1140506
Abstract Full Text PDF–54K
In Vitro Activities of Amphotericin B and Voriconazole against Aleurioconidia from Aspergillus terreus
Cornelia Lass-Flörl, Alexandra Rief, Sandra Leitner, Cornelia Speth, Reinhard Würzner, Manfred P. Dierich
Antimicrob Agents Chemother. 2005 June; 49(6): 2539–2540. doi: 10.1128/AAC.49.6.2539-2540.2005
PMCID:
PMC1140531
Abstract Full Text PDF–41K
Comparative In Vitro Activities of Investigational Peptide Deformylase Inhibitor NVP LBM-415 and Other Agents against Human Mycoplasmas and Ureaplasmas
Ken B. Waites, Nipun B. Reddy, Donna M. Crabb, Lynn B. Duffy
Antimicrob Agents Chemother. 2005 June; 49(6): 2541–2542. doi: 10.1128/AAC.49.6.2541-2542.2005
PMCID:
PMC1140545
Abstract Full Text PDF–45K
Selection of Cross-Resistance following Exposure of Pseudomonas aeruginosa Clinical Isolates to Ciprofloxacin or Cefepime
Samer A. Alyaseen, Kerryl E. Piper, Mark S. Rouse, James M. Steckelberg, Robin Patel
Antimicrob Agents Chemother. 2005 June; 49(6): 2543–2545. doi: 10.1128/AAC.49.6.2543-2545.2005
PMCID:
PMC1140511
Abstract Full Text PDF–43K
Decreasing Prevalence of β-Lactamase Production among Respiratory Tract Isolates of Haemophilus influenzae in the United States
Kris P. Heilmann, Cassie L. Rice, Ashley L. Miller, Norma J. Miller, Susan E. Beekmann, Michael A. Pfaller, Sandra S. Richter, Gary V. Doern
Antimicrob Agents Chemother. 2005 June; 49(6): 2561–2564. doi: 10.1128/AAC.49.6.2561-2564.2005
PMCID:
PMC1140551
Abstract Full Text PDF–54K
Posttreatment Changes in Escherichia coli Antimicrobial Susceptibility Rates among Diarrheic Patients Treated with Ciprofloxacin
Shannon D. Putnam, John W. Sanders, David R. Tribble, David R. Rockabrand, Mark S. Riddle, Patrick J. Rozmajzl, Robert W. Frenck
Antimicrob Agents Chemother. 2005 June; 49(6): 2571–2572. doi: 10.1128/AAC.49.6.2571-2572.2005
PMCID:
PMC1140542
Abstract Full Text PDF–42K
Analytical Procedures
Use of Confocal Microscopy To Analyze the Rate of Vancomycin Penetration through Staphylococcus aureus Biofilms
Kimberly K. Jefferson, Donald A. Goldmann, Gerald B. Pier
Antimicrob Agents Chemother. 2005 June; 49(6): 2467–2473. doi: 10.1128/AAC.49.6.2467-2473.2005
PMCID:
PMC1140491
Abstract Full Text PDF–516K
Antiviral Agents
Phosphorylation of Ribavirin and Viramidine by Adenosine Kinase and Cytosolic 5′-Nucleotidase II: Implications for Ribavirin Metabolism in Erythrocytes
Jim Zhen Wu, Gary Larson, Heli Walker, Jae Hoon Shim, Zhi Hong
Antimicrob Agents Chemother. 2005 June; 49(6): 2164–2171. doi: 10.1128/AAC.49.6.2164-2171.2005
PMCID:
PMC1140532
Abstract Full Text PDF–132K
In Vitro Antiviral Activity and Single-Dose Pharmacokinetics in Humans of a Novel, Orally Bioavailable Inhibitor of Human Rhinovirus 3C Protease
Amy K. Patick, Mary A. Brothers, Fausto Maldonado, Susan Binford, Oscar Maldonado, Shella Fuhrman, Annkatrin Petersen, George J. Smith, III, Leora S. Zalman, Leigh Ann Burns-Naas, Jonathan Q. Tran
Antimicrob Agents Chemother. 2005 June; 49(6): 2267–2275. doi: 10.1128/AAC.49.6.2267-2275.2005
PMCID:
PMC1140523
Abstract Full Text PDF–201K
TMC114, a Novel Human Immunodeficiency Virus Type 1 Protease Inhibitor Active against Protease Inhibitor-Resistant Viruses, Including a Broad Range of Clinical Isolates
Sandra De Meyer, Hilde Azijn, Dominique Surleraux, Dirk Jochmans, Abdellah Tahri, Rudi Pauwels, Piet Wigerinck, Marie-Pierre de Béthune
Antimicrob Agents Chemother. 2005 June; 49(6): 2314–2321. doi: 10.1128/AAC.49.6.2314-2321.2005
PMCID:
PMC1140553
Abstract Full Text PDF–322K
Interferon Alfacon-1 Protects Hamsters from Lethal Pichinde Virus Infection
Brian B. Gowen, Dale L. Barnard, Donald F. Smee, Min-Hui Wong, Anne M. Pace, Kie-Hoon Jung, Scott G. Winslow, Kevin W. Bailey, Lawrence M. Blatt, Robert W. Sidwell
Antimicrob Agents Chemother. 2005 June; 49(6): 2378–2386. doi: 10.1128/AAC.49.6.2378-2386.2005
PMCID:
PMC1140527
Abstract Full Text PDF–163K
Small Molecules VP-14637 and JNJ-2408068 Inhibit Respiratory Syncytial Virus Fusion by Similar Mechanisms
Janet L. Douglas, Marites L. Panis, Edmund Ho, Kuei-Ying Lin, Steve H. Krawczyk, Deborah M. Grant, Ruby Cai, Swami Swaminathan, Xiaowu Chen, Tomas Cihlar
Antimicrob Agents Chemother. 2005 June; 49(6): 2460–2466. doi: 10.1128/AAC.49.6.2460-2466.2005
PMCID:
PMC1140497
Abstract Full Text PDF–503K
Experimental Therapeutics
Bactericidal Activity of the Nitroimidazopyran PA-824 in a Murine Model of Tuberculosis
Sandeep Tyagi, E. Nuermberger, T. Yoshimatsu, K. Williams, I. Rosenthal, N. Lounis, W. Bishai, J. Grosset
Antimicrob Agents Chemother. 2005 June; 49(6): 2289–2293. doi: 10.1128/AAC.49.6.2289-2293.2005
PMCID:
PMC1140529
Abstract Full Text PDF–79K
Preclinical Testing of the Nitroimidazopyran PA-824 for Activity against Mycobacterium tuberculosis in a Series of In Vitro and In Vivo Models
Anne J. Lenaerts, Veronica Gruppo, Karen S. Marietta, Christine M. Johnson, Diane K. Driscoll, Nicholas M. Tompkins, Jerry D. Rose, Robert C. Reynolds, Ian M. Orme
Antimicrob Agents Chemother. 2005 June; 49(6): 2294–2301. doi: 10.1128/AAC.49.6.2294-2301.2005
PMCID:
PMC1140539
Abstract Full Text PDF–120K
Intravesical Nitric Oxide Delivery for Prevention of Catheter-Associated Urinary Tract Infections
Stefan Carlsson, Eddie Weitzberg, Peter Wiklund, Jon O. Lundberg
Antimicrob Agents Chemother. 2005 June; 49(6): 2352–2355. doi: 10.1128/AAC.49.6.2352-2355.2005
PMCID:
PMC1140550
Abstract Full Text PDF–97K
Microdialysis Study of Imipenem Distribution in Skeletal Muscle and Lung Extracellular Fluids of Noninfected Rats
Sandrine Marchand, Claire Dahyot, Isabelle Lamarche, Olivier Mimoz, William Couet
Antimicrob Agents Chemother. 2005 June; 49(6): 2356–2361. doi: 10.1128/AAC.49.6.2356-2361.2005
PMCID:
PMC1140500
Abstract Full Text PDF–117K
Comparable Efficacies of the Antimicrobial Peptide Human Lactoferrin 1-11 and Gentamicin in a Chronic Methicillin-Resistant Staphylococcus aureus Osteomyelitis Model
Christopher Faber, Hein P. Stallmann, D. M. Lyaruu, Uwe Joosten, Christof von Eiff, Arie van Nieuw Amerongen, Paul I. J. M. Wuisman
Antimicrob Agents Chemother. 2005 June; 49(6): 2438–2444. doi: 10.1128/AAC.49.6.2438-2444.2005
PMCID:
PMC1140484
Abstract Full Text PDF–320K
Caspofungin in Combination with Amphotericin B against Candida glabrata
Francesco Barchiesi, Elisabetta Spreghini, Annette W. Fothergill, Daniela Arzeni, Gianfranco Greganti, Daniele Giannini, Michael G. Rinaldi, Giorgio Scalise
Antimicrob Agents Chemother. 2005 June; 49(6): 2546–2549. doi: 10.1128/AAC.49.6.2546-2549.2005
PMCID:
PMC1140549
Abstract Full Text PDF–92K
Clinical Therapeutics
Pharmacodynamic Modeling of the Evolution of Levofloxacin Resistance in Staphylococcus aureus
Jeffrey J. Campion, Philip Chung, Patrick J. McNamara, William B. Titlow, Martin E. Evans
Antimicrob Agents Chemother. 2005 June; 49(6): 2189–2199. doi: 10.1128/AAC.49.6.2189-2199.2005
PMCID:
PMC1140504
Abstract Full Text PDF–381K
Linezolid versus Vancomycin in Treatment of Complicated Skin and Soft Tissue Infections
John Weigelt, Kamal Itani, Dennis Stevens, William Lau, Matthew Dryden, Charles Knirsch, the Linezolid CSSTI Study Group
Antimicrob Agents Chemother. 2005 June; 49(6): 2260–2266. doi: 10.1128/AAC.49.6.2260-2266.2005
PMCID:
PMC1140485
Abstract Full Text PDF–77K
Pharmacology
Penetration of Linezolid into Soft Tissues of Healthy Volunteers after Single and Multiple Doses
Pejman Dehghanyar, Cornelia Bürger, Markus Zeitlinger, Florian Islinger, Florian Kovar, Markus Müller, Charlotte Kloft, Christian Joukhadar
Antimicrob Agents Chemother. 2005 June; 49(6): 2367–2371. doi: 10.1128/AAC.49.6.2367-2371.2005
PMCID:
PMC1140501
Abstract Full Text PDF–77K
Effects of a High-Fat Meal on the Relative Oral Bioavailability of Piperaquine
Ing-Kye Sim, Timothy M. E. Davis, Kenneth F. Ilett
Antimicrob Agents Chemother. 2005 June; 49(6): 2407–2411. doi: 10.1128/AAC.49.6.2407-2411.2005
PMCID:
PMC1140540
Abstract Full Text PDF–90K
Pharmacokinetics and Pharmacodynamics of Imipenem during Continuous Renal Replacement Therapy in Critically Ill Patients
Douglas N. Fish, Isaac Teitelbaum, Edward Abraham
Antimicrob Agents Chemother. 2005 June; 49(6): 2421–2428. doi: 10.1128/AAC.49.6.2421-2428.2005
PMCID:
PMC1140495
Abstract Full Text PDF–100K
Influence of Efflux Transporters on the Accumulation and Efflux of Four Quinolones (Ciprofloxacin, Levofloxacin, Garenoxacin, and Moxifloxacin) in J774 Macrophages
Jean-Michel Michot, Cristina Seral, Françoise Van Bambeke, Marie-Paule Mingeot-Leclercq, Paul M. Tulkens
Antimicrob Agents Chemother. 2005 June; 49(6): 2429–2437. doi: 10.1128/AAC.49.6.2429-2437.2005
PMCID:
PMC1140503
Abstract Full Text PDF–366K
Population Pharmacokinetics of Abacavir in Plasma and Cerebrospinal Fluid
Edmund V. Capparelli, Scott L. Letendre, Ronald J. Ellis, Parul Patel, Diane Holland, J. Allen McCutchan
Antimicrob Agents Chemother. 2005 June; 49(6): 2504–2506. doi: 10.1128/AAC.49.6.2504-2506.2005
PMCID:
PMC1140502
Abstract Full Text PDF–50K
Effect of CYP3A1(23) Induction on Clarithromycin Pharmacokinetics in Rats with Diabetes Mellitus
Yu C. Kim, Joo H. Lee, So H. Kim, Myung G. Lee
Antimicrob Agents Chemother. 2005 June; 49(6): 2528–2532. doi: 10.1128/AAC.49.6.2528-2532.2005
PMCID:
PMC1140488
Abstract Full Text PDF–64K
Levofloxacin Disposition over Time in Aqueous Humor of Patients Undergoing Cataract Surgery
Federico Pea, Ettore Ferrari, Federica Pavan, Derri Roman-Pognuz, Francesco Bandello, Mario Furlanut
Antimicrob Agents Chemother. 2005 June; 49(6): 2554–2557. doi: 10.1128/AAC.49.6.2554-2557.2005
PMCID:
PMC1140509
Abstract Full Text PDF–73K
Letter to the Editor
The ORF1 Gene Located on the Class-1-Integron-Associated Gene Cassette Actually Represents a Novel Fosfomycin Resistance Determinant
Jun Yatsuyanagi, Shioko Saito, Takayuki Konno, Seizaburo Harata, Noriyuki Suzuki, Ken-ichi Amano
Antimicrob Agents Chemother. 2005 June; 49(6): 2573. doi: 10.1128/AAC.49.6.2573.2005
PMCID:
PMC1140483
Full Text PDF–32K
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