This journal provides early access to some articles.
Volume 68(Pt 8); August 1, 2012
Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-l-methionine at 1.7 Å resolution
Udesh de Silva, Zhaoli Zhou, Bernard A. Brown, II
The crystal structure of A. pernix fibrillarin includes a tightly bound S-adenosyl-l-methionine molecule.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 August 1; 68(Pt 8): 854–859. Published online 2012 July 26. doi: 10.1107/S1744309112026528
Alexander Pflug, Kenneth A. Johnson, Richard A. Engh
The anomalous dispersion signal of the bromine-containing kinase inhibitor H-89 was used to characterize discrete binding modes of the compound when complexed with the catalytic subunit of protein kinase A.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 August 1; 68(Pt 8): 873–877. Published online 2012 July 26. doi: 10.1107/S1744309112028655
Binding of the unreactive substrate analog l-2-amino-3-guanidinopropionic acid (dinor-l-arginine) to human arginase I
Edward L. D’Antonio, David W. Christianson
Crystal structures of Mn2 2+- and Co2 2+-substituted human arginase I complexed with an unreactive analog of substrate l-arginine are described at 1.82 and 1.90 Å resolution, respectively.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 August 1; 68(Pt 8): 889–893. Published online 2012 July 27. doi: 10.1107/S1744309112027820
Useable diffraction data from a multiple microdomain-containing crystal of Ascaris suum As-p18 fatty-acid-binding protein using a microfocus beamline
Mads Gabrielsen, Alan Riboldi-Tunnicliffe, Marina Ibáñez-Shimabukuro, Kate Griffiths, Andrew J. Roe, Alan Cooper, Brian O. Smith, Betina Córsico, Malcolm W. Kennedy
As-p18, an unusual fatty-acid-binding protein from a parasitic nematode, was expressed in bacteria, purified and crystallized. The use of a microfocus beamline was essential for data collection.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 August 1; 68(Pt 8): 939–941. Published online 2012 July 31. doi: 10.1107/S1744309112026553
Characterization of crystals of an antibody-recognition fragment of the cancer differentiation antigen mesothelin in complex with the therapeutic antibody MORAb-009
Jichun Ma, Wai Kwan Tang, Lothar Esser, Ira Pastan, Di Xia
The therapeutic antibody MORAb-009 disrupts the interaction of mesothelin and the ovarian cancer antigen CA-125. Crystals have been grown of the Fab fragment derived from MORAb-009 and of its complex with an N-terminal fragment of mesothelin.
Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 August 1; 68(Pt 8): 950–953. Published online 2012 July 31. doi: 10.1107/S1744309112028229