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Table 3.

Transcription factors involved in eye development
Transcription factorTypeESTsNIA 15K
Math5 (atonal homolog 5)bHLH13No
HES-6 (hairy/enhancer of split 6)bHLH6No
Chx10Homeobox5No
SOX11HMG5Yes
mLHX2LIM-homeobox4No
Neurogenin-2bHLH4No
Pax6Paired box4No
RFP-1 (retina-derived POU-domain factor-1)POU3No
Six3Homeobox3No
Six6 (Optx2)Homeobox3No
BHF-1/NeuroDbHLH2No
HES-5 (hairy/enhancer of split 5)bHLH2No
HES-1 (hairy/enhancer of split 1)bHLH2No
Ash1 (achaete-scute homolog 1)bHLH2No
ASH2bHLH2Yes
ROR-beta/retinoid-related orphan receptor (ROR) betaNuclear receptor2No
Rx/Rax (retina and anterior neural fold homeobox gene)Homeobox1No
Math3 (atonal homolog 3)bHLH1No
SOX8HMG1Yes
SOX9HMG1Yes
CASP (homeobox gene Cut alternatively spliced product)Homeobox1Yes
TBX3 (T-box protein)T-box1No
Islet-2LIM-homeobox1No
OC-2 (ONECUT homeodomain class)Homeobox1No