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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
 
Immunity. Author manuscript; available in PMC 2018 January 2.
Published in final edited form as:
PMCID: PMC5749209
NIHMSID: NIHMS922587

Glycans Function as Anchors for Antibodies and Help Drive HIV Broadly Neutralizing Antibody Development

(Immunity 47, 524–537; September 19, 2017)

The authors inadvertently omitted some text from the legend for Figure 4B, making it difficult to interpret the figure. The full and complete legend appears here and online. The authors regret this omission.

(B) Octet binding curves (association: 120 s [180–300] and dissociation: 240 s [300–540]) of CAP256.21 and CAP256.25 Abs with CRF250 trimer, its individual glycan site-eliminated variants and their corresponding a2,6 desialylated versions. The binding curves for the WT CRF250 trimer and each of the glycan variants are depicted in different colors, whereas the responses for the desialylated trimer forms are all shown in red. The binding response of CAP256.25 bnAb with the CRF250 N156A variant is fixed to 0.2 nanometer (nm) for clarity.