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J Oncol Pract. 2014 January; 10(1): 48–54.
Published online 2013 September 10. doi:  10.1200/JOP.2013.000920
PMCID: PMC5706137

Do Community-Based Patient Assistance Programs Affect the Treatment and Well-Being of Patients With Breast Cancer?

Abstract

Purpose:

Patients with breast cancer who need adjuvant treatments often fail to receive them. High-quality, community-based patient-assistance programs are an underused, inexpensive resource to help patients with cancer obtain needed therapy. We sought to determine whether connecting women to patient-assistance programs would reduce underuse of adjuvant therapies.

Methods:

We conducted a randomized trial of 374 women (190 assigned intervention [INT], 184 to usual care [UC]) with early-stage breast cancer who underwent surgery between October 2006 and August 2009. After initial needs assessment, individualized action plans were created to connect INT patients with targeted patient-assistance programs; UC patients received an informational pamphlet. Main outcome measures were receiving adjuvant treatment and obtaining help.

Results:

High rates of INT and UC patients received treatment: 87% INT versus 91% UC women who underwent lumpectomy received radiotherapy (P = .39); 93% INT versus 86% UC women with estrogen receptor (ER) –negative tumors ≥ 1 cm received chemotherapy (P = .42); 92% INT versus 93% UC women with ER-positive tumors ≥ 1 cm received hormonal therapy (P = .80). Many women reported needs: 63% had informational; 55%, psychosocial; and 53%, practical needs. High rates of INT patients with needs connected with a program within 2 weeks (92%). At 6 months, INT and UC women used patient-assistance programs at similar rates (75% v 76%; P = .54). Women with informational or psychosocial needs were more likely to receive help (relative risk [RR], 1.77; 95% CI, 1.51 to 1.90 and RR, 1.37; 95% CI, 1.06 to 1.61, respectively).

Conclusion:

INT and UC patients received high rates of adjuvant treatment regardless of trial assignment. Patients with breast cancer who connect to relevant patient assistance programs receive useful informational and psychosocial but not practical help.

Introduction

Community-based cancer assistance programs for patients with cancer can help patients learn about cancer, tests, and treatments; cope with psychosocial distress; overcome access challenges; and get needed treatment.1,2 Programs vary, ranging from those with a narrow focus, providing only counseling or transportation, to those offering a full array of services. Typically staffed by professionals and peer volunteers, programs are often free or low cost and present a great opportunity for patients at risk of foregoing treatment because of insufficient knowledge or challenges to accessing needed care,38 as well as for hospitals facing fiscal strain and limited ability to support patient navigators. Such programs abound, yet many patients with cancer are unaware of them, and programs are underused.2,812 There are few data assessing use of these programs or their effects on receipt of needed care among newly diagnosed patients with cancer. We conducted a randomized controlled trial to determine whether connecting women with breast cancer requiring postsurgical adjuvant treatment1215 to high-quality patient assistance programs versus usual care would reduce underuse of needed therapies and meet women's informational, emotional, and practical needs.

Methods

Setting and Participants

We recruited eight inner-city hospitals: four municipal and four tertiary referral centers. Women were recruited within 2 to 4 weeks after definitive surgical treatment for early-stage breast cancer. Women were eligible if postsurgical adjuvant treatment, such as irradiation after lumpectomy or hormonal or chemotherapy for tumors ≥ 1 cm or smaller tumors with poor differentiation or lymphovascular invasion, was recommended. Women who did not speak English or Spanish or could not provide informed consent were excluded. Women were block–randomly assigned to intervention (INT) or usual care (UC) after a baseline survey at the needs assessment. The study was approved by the institutional review boards of all eight participating hospitals.

Study Design and INT

We convened a steering committee of experts in psycho-oncology and assistance for patients with cancer to advise on the needs of patients with breast cancer and relevant resources and to tailor the needs assessment tool and outreach worker training.

We created a resource inventory of high-quality patient-assistance programs that provided information and services related to breast cancer and its treatment, such as psychosocial counseling, help with finances (including insurance and medication), and assistance with transportation. Resources were then classified by category of need addressed (ie, practical/access, information, psychosocial, other), language, and location; the inventory was computerized. An algorithm matched available resources with patient characteristics, needs, and preferences, including geographic location, age, language, preferred media for communication (print, Internet, telephone, face to face), and counseling (peer or professional). This process is detailed elsewhere.9

A brief needs assessment tool was created (Appendix, online only), because existing tools were impractically lengthy (> 100 items) for patients undergoing cancer treatment or their caregivers.1623

The INT informed, enabled, and reinforced connections to patient assistance programs.2426 The first component of the INT, informing women about programs, was based on prior work attributing low rates of program attendance to women's lack of knowledge that such support was available.2,8,10,11,27,28 The second, creating an action plan, was designed to enable and ensure program contact. The third, reserved for women in the intervention arm who still did not connect, was an outreach worker who identified barriers and provided more targeted approaches to enable connection with programs that addressed a broad range of needs.

All patients were surveyed at baseline to measure breast cancer experiences, knowledge, attitudes, and beliefs, followed by a needs assessment (Appendix, online only). Using the algorithm and needs assessment, we identified three high-quality programs to target each identified need. The research assistant then created an individualized action plan with each patient to enable program contact. Action plan and related print materials were mailed. UC patients were sent a New York State Department of Health pamphlet about breast cancer that included resource contact information.29

Two weeks later, we called all patients to confirm receipt of mailed materials and remind them of the 6-month follow-up survey (Fig 1). INT patients were asked whether they connected with the programs specified in their action plan. Participants who had not yet connected with their action plan program were asked if they still needed help. INT women with unaddressed needs were then assigned an outreach worker to help them contact a program. Outreach workers, individuals who worked with women with breast cancer at that hospital, were trained to identify and address barriers that interfered with women's connecting to a patient assistance program.

Figure 1.
CONSORT diagram.

We surveyed participants at 6 months about their experiences with care, health status (Short Form–12 [SF-12] questionnaire), social support,30 self-efficacy, knowledge, attitudes, and beliefs about breast cancer and its treatment, patient assistance programs contacted, and help received from programs.

Primary Outcomes and Analysis

Primary outcome measures included treatment rates and receiving help for needs. Treatment data, based on medical record abstraction, began in the surgeon's office. Treating medical and radiation oncologists were identified by surgeons and via inpatient and outpatient medical record review. When unable to identify treating oncologists through these means, we asked patients. Comorbidity was measured with the Charlson comorbidity index,31 and physical and mental health SF-12 scores were calculated using Hays' algorithms.32 Scale reliability was assessed by calculating coefficient alpha.33 Reliability estimates were 0.74, 0.64, and 0.60 for self-efficacy, emotional, and instrumental social support,30 respectively.

We determined whether a patient had contacted a program based on the 2-week telephone call. Whether a patient got help for her need was based on the 6-month survey, which asked women who connected with programs to specify the type of help provided that was helpful (eg, information about cancer and its treatment; emotional support; financial counseling; help finding medical care; accompaniment to appointments; help with other life responsibilities, which enabled them to receive treatments, like child care or transportation; or other kind of help).

Summary statistics were used to describe baseline demographics, χ2 tests were used for categorical variables, and t tests or analysis of variance were used for continuous variables to assess group differences. Intention-to-treat analysis of primary outcomes was carried out to assess effectiveness of the patient assistance intervention. Logistic regression models were fit to assess factors potentially associated with the primary outcomes, underuse of adjuvant treatment and help received. Because rates of program contact were similar in both trial arms, separate analyses were performed to test the effect of patient assistance programs on outcomes. All analyses were performed using SAS software (version 9.1.3; SAS Institute, Cary, NC), with the type 1 error rate fixed at 0.05 (two tailed). We assumed a 25% underuse rate30 and powered to detect a 50% reduction to 12%, requiring 154 women per trial arm.

Results

Participant Characteristics

Consent to participate was obtained from 374 women in need of adjuvant treatment after surgery for new primary, early-stage breast cancer (Fig 1). Those who refused participation were older than enrollees (age 61 v 57 years; P < .001), with no difference in stage, hospital, or surgery type. Of women who consented, 190 were randomly assigned to INT and 184 to UC, with minority participants evenly divided between trial arms (Table 1). Women's average age was 56.7 years (standard deviation [SD], 12.0); 79% were high school graduates, and approximately half lived with a significant other.

Table 1.
Baseline Patient Demographic and Clinical Characteristics by Trial Arm Assignment

A large majority of women participated at 6-month follow-up: 333 (89%) of 374; two of the 41 patients lost to follow-up died, seven refused participation, and 32 were unreachable. There were no differences in age, stage of cancer, type of surgery, insurance, or rate of adjuvant treatment received between those lost to follow-up and those remaining in the study. There was a greater loss to follow-up among black women (black, 19% v Hispanic, 11% v white, 7%; P = .07), albeit not statistically significant.

Needs

The majority of women reported a need (288 [77%] of 374; 79 reported one; 67, two; and 142, three needs); 143 were randomly assigned to NT and 145 to UC. Rates were similar across type of need: 237 (63%), informational; 205 (55%), psychosocial; 197 (53%), practical/access. Hispanic women reported more needs compared with black or white women (2.5 v 1.9 v 1.1, respectively; P < .05) and more in each category (informational: 85% v 80% v 41%; P < .001; psychosocial: 81% v 57% v 37%; P < .001; and practical: 81% v 52% v 34%; P < .001). There were no differences in the type or frequency of expressed needs between trial arms and no differences by demographics or disease stage.

Receipt of Trial Materials

There were no differences between INT and control arms in the number of women reporting receipt of written information: 98% (186 of 190) in INT arm; 95% (175 of 184) in UC arm (P = .68). Six UC and three INT patients were unreachable.

Program Connection

The intervention successfully connected 101 (92%) of 110 INT women with needs to a program. Of the 143 INT patients with needs, 23% (33 of 143) reported their needs resolved without contacting a program. The majority of women with ongoing needs (62% [89 of 143]) used their action plan to make contact; however, 18 INT women did not connect with a program as per their action plan. Sixteen of these 18 women spoke with an outreach worker; 12 of the 16 connected with a program, but four said they “did not have time.” Five patients ceased to participate: one had physical constraints, one was not assigned to an outreach worker, and three were unreachable. There were no differences between women who were and were not referred to an outreach worker in age, race, income, education, insurance, language, living situation (ie, alone), tumor stage, type of hospital, health literacy, or family history. However, those referred did express more needs (mean, 2.4; SD, 0.8 v mean, 1.7; SD, 12; P = .01).

Help Received

A majority of women (76%) reported receiving specific help from the programs, with no difference between INT and UC patients. Only 7% of INT and 4% of UC patients with practical access needs reported receiving help from a program. Higher proportions of minority women reported being helped for identified needs (Hispanic, 61% v black, 54% v white, 40%; P = .035). Help received was associated with type of need; women with informational or psychosocial needs received useful help from programs, whereas those with practical needs did not. Receipt of help did not differ between INT and control arms (Table 2). Because program contact rates were similar between trial arms, we looked to see whether connecting with programs had an effect. Among women who had a need, regardless of trial arm assignment, 79% of those who connected with a patient assistance program, as compared with 35% of those who did not connect, reported having some or all of their needs met (P < .001; Appendix Table A1, online only).

Table 2.
Outcomes: Help Received From Patient Assistance Programs and Treatment Rates by Trial Arm Assignment

Treatment Received

Rates were high for all types of treatment in both arms (Table 2; INT, 87% v UC, 91% for irradiation after lumpectomy; P = .39; INT, 93% v UC, 86% for chemotherapy for estrogen receptor [ER] –negative tumors; P = .42; INT, 92% v UC, 93% for hormonal therapy for ER-positive tumors; P = .80). Use of therapy was not related to race, education, insurance, stage, comorbidity, or type or number of needs. Multivariable logistic models identified two factors related to treatment use: underuse was greater among older compared with younger women (odds ratio, 2.805; 95% CI, 1.307 to 6.018 for women age ≥ 70 years) and lower for women with more social support (Table 3).

Table 3.
Multivariable Models of Help Received From Patient Assistance Programs and of Underuse of Adjuvant Treatment

Participation Effect

To assess whether study participation (ie, Hawthorne effect), patient selection (ie, healthy volunteer effect), or both led to an overestimate of treatment rates, we compared trial rates with data from the SEER program for patients diagnosed in the years of our study. We assessed rates of radiation therapy after breast-conserving surgery, because these are more reliable than chemotherapy and hormonal treatment reports.3436 Treatment rates in our trial were significantly higher than the SEER rates for the overall population (88% v 69%; P < .001), within age groups (≥ 70 years: 79% v 61%; P = .02; < 70 years: 91% v 72%; P < .001), and within racial groups (blacks: 93% v 62%; P < .001 and whites: 85% v 69%; P < .001).

Discussion

The findings of our study suggest that a large proportion of women with a new breast cancer diagnosis have needs, and a high proportion of women enrolled onto a trial to enable connection with patient assistance programs connect with programs, regardless of trial arm assignment. INT did not result in greater proportions of women initiating contact, connecting with programs, or receiving treatment. Because both INT and control arms received information about cancer treatment and patient assistance programs, it is possible that simply prompting about incoming information on breast cancer treatment and resources may be adequate for most women. Few seemed to require more intensive or targeted INTs. Of note, both treatment rates and use of patient assistance programs were significantly higher than national and previously reported rates,2,27,28,3739 suggesting a possible healthy volunteer bias or Hawthorne effect.

Similar proportions of women in both trial arms reported contact with patient assistance programs. To ethically conduct this study, it was imperative to provide all patients with information about breast cancer and its treatment. Our INT focused on educating women about these programs, because prior work attributed low program attendance to women's lack of knowledge of their availability. Most INT women contacted programs when simply provided with contact information and stimulated to make contact. Few required additional outreach, and there were no distinguishing characteristics of this vulnerable subgroup to inform targeting future interventions. Similarly, prompting and providing UC trial participants with information about programs and treatment was enough to enable them to connect to programs.

However, contact did not assure satisfaction of all needs. Although informational and emotional needs were met for a majority of women (INT, 58%; UC, 54%), receipt of assistance for practical needs was distressingly low. At 6 months, only 6% of women with a practical need reported getting help. Programs face great challenges, particularly in times of economic constraint, to find funds for patients to supplement rent, transportation, or medication payments. This is particularly relevant for minority women, because they are at increased risk of having practical needs and of losing their jobs within 6 months of breast cancer diagnosis.40 It is noteworthy that three quarters of women with needs who contacted programs did get useful help.

Treatment rates were decidedly higher than anticipated. During the time between proposal writing and trial recruitment, one hospital implemented a patient navigator program. It is unlikely that patient navigation resulted in the high treatments rates, because the two hospitals without navigator programs—one municipal and one tertiary referral—had extremely low underuse rates: 7% and 4%, respectively. All hospitals had either some form of patient navigation in place or ongoing relationships with programs such as SHARE or CancerCare. All had tumor boards and breast cancer leadership committed to ensuring multidisciplinary care. The specific causes of improved care are uncertain, because basic structural components that affect cancer care quality did not noticeably change during this timeframe.4143

Despite national trends toward improved treatment rates,3739,44 SEER data for the years of our study show significantly higher underuse rates compared with our findings (31% v 12%). It is unlikely that this discrepancy is solely the result of SEER underreporting, because the observed is greater than the expected rate difference.45 We believe this difference represents a healthy volunteer bias or Hawthorne effect inherent in patients who enroll onto clinical trials. In fact, women who refused to participate were older—the group at greater risk of underuse. The extremely low rates of underuse point to a gap in what is considered acceptable for a randomized clinical trial—namely, the absence of a base rate, a measure of the proportion of women receiving necessary adjuvant treatment. Indeed, a review of records might show no benefit for booklet alone and perhaps benefit for the more complete intervention. We were unable to determine whether treatment rates in the participating institutions differed between study participants and nonparticipants, because all IRBs required patient consent to review medical records, and nonparticipants did not provide consent. Thus, it is impossible for us to exclude a Hawthorne effect or selection bias among our study participants. Until base rate data and more complex designs are available, and IRBs are responsive to these challenges, the value of clinical trial data may be of limited use in evaluating the efficacy—let alone the effectiveness—of behavioral interventions.46

The limitations of this study include similar rates of contact with patient assistance programs—our intervention of interest—by INT and UC participants, accompanied by similar postsurgical treatment rates. The study was conducted in New York City teaching hospitals, thus limiting generalizability. However, participating hospitals varied in size, volume, populations served, and fiscal structure. This was an effectiveness—not an efficacy—study, so we did not attempt to control the content of interactions of patient assistance programs with our patients, nor did we interact with or attempt to influence existing programs at the participating hospitals. We conducted our survey in English and Spanish; findings may not apply to women with limited proficiency in these languages. The number of women who at 6 months recalled receiving written information was similar between INT and control patients (75% v 76%; P = .54) but was significantly lower than the 95% recall at 2 weeks. Because we did not directly refer control patients to programs, we did not assess their connections at 2 weeks and so were unable to determine whether short-term connections differed between the trial arms, an important limitation given the decline in recall seen among INT patients. We asked women what type of useful help they received, such as help with information, psychosocial support, transportation, finances, or other. We did not ask for additional details about their needs or help received. Importantly, 23% of women had their needs resolved within 2 weeks without program connection. This quick resolution suggests a changing pattern of needs in recently diagnosed patients with cancer, who may require a more tactical needs assessment.47,48

What does this study say about the effectiveness of high-quality, community-based patient assistance programs? Although these programs can provide patients with cancer with resources and support beyond those provided by hospitals at little to no cost to the institution, they do not affect rates of treatment, because treatment rates are high. They can provide informational and psychosocial help but are limited in addressing practical access challenges. Whether such programs would have stronger effects on treatment rates in populations with differing levels of need and lower treatment rates is unknown. In the interim, matching women to programs that target resources most accurately and efficiently can resolve informational and psychosocial needs.

Acknowledgment

Clinical trial information: NCT00233077. Supported by National Cancer Institute Grant No. 5R01CA107051. We thank Shalini Arora, MD, Ivis Febus-Sampayo, Marianne Glasel, Gladys Helper, Carolyn Messner, DSW, Alyson Moadel, PhD, George Raptis, MD, and Alice Yaker, JD.

Appendix

To identify practical/access needs:

“Sometimes women are concerned with the way they are going to pay for and get to treatment for their breast cancer. Are these things you would like to know more about?”

“Do you need help getting medical coverage or insurance, or getting your insurance to cover the cost of your treatment?”

To identify informational needs:

“Sometimes, women need help understanding what breast cancer is and how it's treated. Would you like more information about breast cancer and treatment?”

To identify psychosocial needs:

“Sometimes, women are concerned about what it means to have breast cancer or how to deal with a breast cancer diagnosis. Is this something that concerns you?”

“Would you be interested in finding out about organizations that provide support to individuals and groups, or offer support groups or counseling?”

Table A1.

Characteristics and Outcomes of Patients Using Patient Assistance Programs*

CharacteristicPatient Assistance Program
P
Yes
No
No.%No.%
Total patients1103322367
Age, years.304
    Mean55.757
    SD11.611.9
Race.882
    White504510547
    Hispanic34316730
    Black20184118
    Asian6584
    Other0021
Insurance.191
    Commercial585313360
    Medicare only17164420
    Medicaid32294319
    Uninsured2231
Low income (< $15,000 per year)33335227.344
Education level, years.354
    Mean14.413.9
    SD4.54.5
Married/living with partner444011753.035
Stage.479
    1605513259
    250459142
Type of need
    Informational736613761.400
    Psychosocial736611050.005
    Practical/access666011150.082
No. of needs.136
    019175826
    122205022
    217153717
    352477835
Baseline emotional health.452
    Mean5253
    SD10.610.1
Baseline physical health.781
    Mean5151
    SD10.79.9
Emotional social support.319
    Mean8183
    SD19.617.9
Instrumental social support.574
    Mean7273
    SD26.724.0
Self-efficacy (sd).431
    Mean8381
    SD16.919.7
Treatments received
    RT post-BCS (n = 189)528711690.620
    Chemotherapy
        ≥ 1 cm and HR negative (n = 64)17854091.668
        ≥ 1 cm (n = 279)6568126681.000
    Hormonal therapy (n = 209)648812392.315
6-month emotional health.412
    Mean4950
    SD11.110.4
6-month physical health.674
    Mean4646
    SD11.211.1
Useful help received (n = 333)87797835< .001

Abbreviations: BCS, breast-conserving surgery; HR, hormone receptor; SD, standard deviation.

*Analysis based on use of programs, not intent to treat.

Authors' Disclosures of Potential Conflicts of Interest

The author(s) indicated no potential conflicts of interest.

Author Contributions

Conception and design: Nina A. Bickell, Andrea N. Geduld, Howard Leventhal

Collection and assembly of data: Nina A. Bickell, Kathie-Ann Joseph, Joseph A. Sparano, Soji Oluwole, Tehillah Menes, Anitha Srinivasan, Rebeca Franco, Kezhen Fei

Data analysis and interpretation: Nina A. Bickell, Andrea N. Geduld, Kathie-Ann Joseph, Joseph A. Sparano, M. Margaret Kemeny, Rebeca Franco, Kezhen Fei, Howard Leventhal

Manuscript writing: All authors

Final approval of manuscript: All authors

References

1. Hewitt M, Greenfield S, Stovall E.: From Cancer Patient to Cancer Survivor: Lost in Transition 2006. Washington, DC: National Academies Press
2. Shelby RA Taylor KL Kerner JF, etal: The role of community-based and philanthropic organizations in meeting cancer patient and caregiver needs CA Cancer J Clin 52:229–246,2002. [PubMed]
3. Battaglia TA Roloff K Posner MA, etal: Improving follow-up to abnormal breast cancer screening in an urban population: A patient navigation intervention Cancer 109:359–367,2007. suppl [PubMed]
4. Donelan K Mailhot JR Dutwin D, etal: Patient perspectives of clinical care and patient navigation in follow-up of abnormal mammography J Gen Intern Med 26:116–122,2011. [PMC free article] [PubMed]
5. Freeman HP, Rodriguez RL.: History and principles of patient navigation Cancer 117:3539–3542,2011. suppl [PMC free article] [PubMed]
6. Freund KM.: Patient navigation: The promise to reduce health disparities J Gen Intern Med 26:110–112,2011. [PMC free article] [PubMed]
7. Phillips CE Rothstein JD Beaver K, etal: Patient navigation to increase mammography screening among inner city women J Gen Intern Med 26:123–129,2011. [PMC free article] [PubMed]
8. Arora NK Johnson P Gustafson DH, etal: Barriers to information access, perceived health competence, and psychosocial health outcomes: Test of a mediation model in a breast cancer sample Patient Educ Couns 47:37–46,2002. [PubMed]
9. Cohen A Mohan KN Fei K, etal: Are patient assistance programmes able to meet the needs of New York City women with breast cancer? Women's perspectives Eur J Cancer Care (Engl) 18:50–56,2009. [PubMed]
10. Mor V Allen SM Siegel K, etal: Determinants of need and unmet need among cancer patients residing at home Health Serv Res 27:337–360,1992. [PMC free article] [PubMed]
11. Mor V Masterson-Allen S Houts P, etal: The changing needs of patients with cancer at home: A longitudinal view Cancer 69:829–838,1992. [PubMed]
12. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials Lancet 365:1687–1717,2005. Early Breast Cancer Trialists' Collaborative Group (EBCTCG) [PubMed]
13. National Comprehensive Cancer Network. NCCN Clinical Practice Guidelines in Oncology: Breast Cancer, Version 1.2010. http://www.nccn.org/professionals/physician_gls/f_guidelines.asp#site.
14. Clarke M Collins R Darby S, etal: Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials Lancet 366:2087–2106,2005. [PubMed]
15. Darby S McGale P Correa C, etal: Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: Meta-analysis of individual patient data for 10,801 women in 17 randomised trials Lancet 378:1707–1716,2011. [PMC free article] [PubMed]
16. Campbell SH Sanson-Fisher R Turner D, etal: Psychometric properties of cancer survivors' unmet needs survey Support Care Cancer 19:221–230,2010. [PubMed]
17. Cossich T, Schofield P, McLachlan SA.: Validation of the cancer needs questionnaire (CNQ) short-form version in an ambulatory cancer setting Qual Life Res 13:1225–1233,2004. [PubMed]
18. Sanson-Fisher R Girgis A Boyes A, etal: The unmet supportive care needs of patients with cancer: Supportive Care Review Group Cancer 88:226–237,2000. [PubMed]
19. Thewes B Butow P Girgis A, etal: The psychosocial needs of breast cancer survivors: A qualitative study of the shared and unique needs of younger versus older survivors Psychooncology 13:177–189,2004. [PubMed]
20. Wen KY, Gustafson DH.: Needs assessment for cancer patients and their families Health Qual Life Outcomes 2:11,2004. [PMC free article] [PubMed]
21. Rutten LJ Arora NK Bakos AD, etal: Information needs and sources of information among cancer patients: A systematic review of research (1980-2003) Patient Educ Couns 57:250–261,2005. [PubMed]
22. Barg FK Cronholm PF Straton JB, etal: Unmet psychosocial needs of Pennsylvanians with cancer: 1986-2005 Cancer 110:631–639,2007. [PubMed]
23. Degner LF Kristjanson LJ Bowman D, etal: Information needs and decisional preferences in women with breast cancer JAMA 277:1485–1492,1997. [PubMed]
24. Glanz K, Rimer B.: Theory at a Glance: A Guide for Health Promotion Practice 2005. ed 2 Bethesda, MD: National Cancer Institute, NIH publication 05-3896
25. Leventhal H, Diefenbach M, Leventhal E.: Illness cognition: Using common sense to understand treatment adherence and affect cognition interactions Cognit Ther Res 16:143–163,1992
26. Leventhal H, Nerenz D, Steele D, editors. : Illness Representation and Coping With Health Threats: A Handbook of Psychology and Health 1984. Hillsdale, NH: A. Baum and J. Singer
27. Bickell NA Weidmann J Fei K, etal: Underuse of breast cancer adjuvant treatment: Patient knowledge, beliefs, and medical mistrust J Clin Oncol 27:5160–5167,2009. [PMC free article] [PubMed]
28. Bickell NA LePar F Wang JJ, etal: Lost opportunities: Physicians' reasons and disparities in breast cancer treatment J Clin Oncol 25:2516–2521,2007. [PubMed]
29. New York State Department of Health. Breast cancer treatment: What you should know. http://www.health.ny.gov/publications/0401/
30. Strogatz DS Croft JB James SA, etal: Social support, stress, and blood pressure in black adults Epidemiology 8:482–487,1997. [PubMed]
31. Charlson ME Pompei P Ales KL, etal: A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation J Chronic Dis 40:373–383,1987. [PubMed]
32. Hays RD.: SAS Code to Score the SF-12 Version 2.0 2004. Los Angeles, CA: University of California Los Angeles
33. Cronbach LJ.: Coefficient alpha and the internal structure of tests Psychometrika 16:297–334,1951
34. Lund JL Stürmer T Harlan LC, etal: Identifying specific chemotherapeutic agents in Medicare data: A validation study Med Care 51:e27–e34,2013. [PMC free article] [PubMed]
35. Virnig BA Warren JL Cooper GS, etal: Studying radiation therapy using SEER-Medicare linked data Med Care 40:IV49–IV54,2002. suppl [PubMed]
36. Warren JL Harlan LC Fahey A, etal: Utility of the SEER-Medicare data to identify chemotherapy use Med Care 40:IV55–IV61,2002. suppl [PubMed]
37. Gross CP Smith BD Wolf E, etal: Racial disparities in cancer therapy: Did the gap narrow between 1992 and 2002? Cancer 112:900–908,2008. [PMC free article] [PubMed]
38. Neugut AI Hillyer GC Kushi LH, etal: Non-initiation of adjuvant hormonal therapy in women with hormone receptor-positive breast cancer: The Breast Cancer Quality of Care Study (BQUAL) Breast Cancer Res Treat 134:419–428,2012. [PMC free article] [PubMed]
39. Ooi SL, Martinez ME, Li CI.: Disparities in breast cancer characteristics and outcomes by race/ethnicity Breast Cancer Res Treat 127:729–738,2011. [PMC free article] [PubMed]
40. Bradley CJ Neumark D Luo Z, etal: Employment and cancer: Findings from a longitudinal study of breast and prostate cancer survivors Cancer Invest 25:47–54,2007. [PubMed]
41. Bickell NA, Young GJ.: Coordination of care for early-stage breast cancer patients J Gen Intern Med 16:737–742,2001. [PMC free article] [PubMed]
42. McCarthy M Gonzalez-Izquierdo A Sherlaw-Johnson C, etal: Comparative indicators for cancer network management in England: Availability, characteristics and presentation BMC Health Serv Res 8:45,2008. [PMC free article] [PubMed]
43. Zapka J Taplin SH Price RA, etal: Factors in quality care: The case of follow-up to abnormal cancer screening tests—Problems in the steps and interfaces of care J Natl Cancer Inst Monogr 2010:58–71,2010. [PMC free article] [PubMed]
44. Greenberg CC Lipsitz SR Neville B, etal: Receipt of appropriate surgical care for Medicare beneficiaries with cancer Arch Surg 146:1128–1134,2011. [PMC free article] [PubMed]
45. Walker GV Giordano SH Williams M, etal: Muddy water? Variation in reporting receipt of breast cancer radiation therapy by population-based tumor registries Int J Radiat Oncol Biol Phys 86:686–693,2013. [PMC free article] [PubMed]
46. Shadish WR, Cook TD, Campbell DT.: Experimental and Quasi-Experimental Designs for Generalized Causal Inference 2002. ed 2 Boston, MA: Houghton Mifflin
47. Lally RM, Underhill ML.: Transition to breast cancer survivorship: A longitudinal qualitative follow-up study of two-year survivors J Psychosoc Oncol 30:97–127,2012. [PubMed]
48. Mullan F.: Seasons of survival: Reflections of a physician with cancer N Engl J Med 313:270–273,1985 [PubMed]

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