Search tips
Search criteria 


Logo of bmjcrBMJ Case ReportsVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
BMJ Case Rep. 2012; 2012: bcr2012006502.
Published online 2012 July 9. doi:  10.1136/bcr-2012-006502
PMCID: PMC5597316
Images in…

Don't forget ‘simple’ causes of abdominal pain


A 6-year-old male child presented with intermittent abdominal pain and alternating bowel since 1 year. Lab tests resulted negative, except for high erythrocyte sedimentation rate. Stool studies—occult blood and microbiology—resulted unremarkable. Symptoms were persistent and started impairing the child's life everyday. Despite failure to thrive, abdominal pain at night was not registered. Abdomen ultrasound showed thickening of distal ileum, and mildly enlarged mesenteric lymph nodes. At lower endoscopy in the distal ileum worms crawling on the wall were seen (see Video 1). Direct microscopy showed Enterobius vermicularis (EV). Random biopsies of the colon revealed lymph-node hyperplasia. The patient was twice successfully treated with mebendazole (200 mg/day).

Video 1

Lower endoscopy revealed pinworm crawling on the wall of the distal ileum.

EV—pinworm—is the most common helminthes infection in Western Europe and North America.1 The infestation occurs worldwide, affecting all socioeconomic groups, particularly school-aged children. The interhuman transmission is oro-faecal. Most patients are asymptomatic, and when symptoms are present, peri-anal itching—especially at night—is the most common clinical feature.

The child came to our observation after first-line investigations. Stool exams (microbiology+scotch-test) should have been repeated before performing lower endoscopy as indicated for abdominal pain with ‘red-flags’,2 such as in the suspicion of inflammatory bowel diseases (IBDs). Infectious diseases must be strongly excluded before thinking of inflammatory ones. With the improvement in scientific knowledge and in diagnostic accuracy, it is easy to focus the attention on major diseases despite minor ones. In our case we performed endoscopy in the suspicion of IBDs (prevalence 0.6%)3 but diagnosed parasitosis (prevalence 30–40%).1


Competing interests: None.

Patient consent: Obtained.


1. Piperaki ET, Spanakos G, Patsantara G, et al. Characterization of Enterobius vermicularis in a human population, employing a molecular-based method from adhesive tape samples. Mol Cell Probes 2011;25:121–5. [PubMed]
2. Noe JD, Li BU. Navigating recurrent abdominal pain through clinical clues, red flags, and initial testing. Pediatr Ann 2009;38:259–66. [PubMed]
3. Molodecky NA, Soon IS, Rabi DM, et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology 2012;142:46–54. [PubMed]

Articles from BMJ Case Reports are provided here courtesy of BMJ Publishing Group