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An overview of Personal Profiles can be found at http://www.moloncol.org.
Director of Research, The Netherlands Cancer Institute. Professor of Experimental Genetics of Inherited Diseases, University of Amsterdam.
Anton Berns studied biochemistry at the University of Nijmegen and received his Masters degree in 1969 and his PhD in 1972 from that same University. He did his postdoctoral training in the group of Rudolf Jaenisch at the Salk Institute in La Jolla, CA, where he studied the role of retroviruses in causing lymphomas in mice. In 1976 he returned to the University of Nijmegen where he became junior staff member. His group explored proviral insertional mutagenesis as a means to identify new oncogenes. In 1985 he was appointed as staff scientist at the Netherlands Cancer Institute and in 1986 he became head of the Division of Molecular Genetics of the Institute. Here his group did pioneering work to generate and utilize genetically modified mice as a tool to search for new cancer genes. Currently, his group focuses on the development and use of advanced mouse models for cancer. Themes of his current research are: i. Establishing genotype–phenotype correlations of tumors using Cre‐mediated switching of multiple oncogenes/tumor suppressor genes in a spatiotemporal controlled fashion with emphasis on lung cancer models, and ii. The use of high throughput proviral insertional mutagenesis to identify components in signaling pathways relevant for cancer. His group consists of approximately 12 post‐docs and graduate students. In 1999, he was appointed as Director of Research and Chairman of the Board of Directors of the Netherlands Cancer Institute/Antoni van Leeuwenhoek Hospital.
(2009), Personal Profiles, Molecular Oncology, 3, doi: 10.1016/j.molonc.2009.07.005.