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Logo of jbcThe Journal of Biological Chemistry
 
J Biol Chem. 2017 March 31; 292(13): 5608.
PMCID: PMC5392701

Positive and negative roles of p85α and p85β regulatory subunits of phosphoinositide 3-kinase in insulin signaling.

VOLUME 278 (2003) PAGES 48453–48466

This article has been withdrawn by the authors. In many of the experiments reported in this study, cells from mice of four genotypes were used (wild-type, p85α−/−, p85α+/−, and p85β−/−), but data from only three of the genotypes (wild-type, p85α−/−, and p85β−/−) were included in the final paper. As a result, there was splicing of the figures of several autoradiograms, which led to several duplicated or mislabeled lanes in the Western blots in Figs. 2B, 3C, and 5B. Although the experimental data generated in the lab from the same time period support the original conclusions of the study, and the studies by this lab and others have confirmed and extended the conclusions of the manuscript, in the interest of maintaining accuracy in the published scientific literature and because the initial figures were not up to the standards of JBC, the authors wish to withdraw this article. The authors apologize for these errors.


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