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YJBM Volume 90, Issue 1. Focus: Drug Development
From initial discovery to final approval and marketing, drug development is a lengthly and strictly regulated process. The long and winding road of development is marked by distinct milestones; beginning with molecular testing and discovery, a promising drug is then tested in animal populations, before moving on to numerous phases of human clinical trials that begin with a small number of participants and gradually expand in scope as the efficacy, dosage, and potential side effects are calculated with increasing accuracy. The rate of failure is high, but drugs that are finally approved by regulatory bodies can offer hope to millions. Original cover design by Peter Harris.