PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of hexLink to Publisher's site
 
Health Expect. 2017 April; 20(2): 298–308.
Published online 2016 May 12. doi:  10.1111/hex.12458
PMCID: PMC5354055

Process and impact of patient involvement in a systematic review of shared decision making in primary care consultations

Catherine Hyde, MB ChB MScMedEd MRCGP, MPhil student,corresponding author 1 Kate M. Dunn, BSc Hons MPhil PhD, Professor of Epidemiology, 1 Adele Higginbottom, PPIE Project Co‐ordinator, 1 and Carolyn A. Chew‐Graham, BSc MBChB MD FRCGP I, Professor of General Practice Research 1 , 2

Abstract

Background

Patient and public involvement and engagement (PPIE) in systematic reviews remains uncommon, despite the policy imperative for patient involvement in research. The aim of this study was to investigate the process and impact of collaborating with members of a patient Research User Group (RUG) on a systematic review about shared decision making around prescribing analgesia in primary care consultations.

Methods

Five members of an established patient RUG collaborated with researchers undertaking a systematic review with narrative synthesis, through workshops held at three time‐points. These addressed the following: designing the protocol, interpreting the results and planning dissemination. Support from a RUG coordinator and user support worker facilitated collaboration throughout the review process. Researchers reflected on how PPIE modified the review at each time‐point.

Results

RUG members identified factors important in shared decision making around analgesic prescribing additional to those initially proposed by the research team. Search terms and specific outcomes of interest were amended to reflect these additional factors. Thirty of the 39 patient‐identified factors were absent in the published literature. The categories of factors identified were used as a framework for the narrative synthesis and for reporting results. RUG members prioritized options for disseminating the results.

Conclusion

PPIE collaboration throughout the systematic review impacted on the scope of the review, highlighting gaps in the literature that were important to patients. Impact on interpretation and dissemination of findings ensured the review directly reflected patient priorities. Challenges and strategies to facilitate PPIE involvement in systematic reviews and suggestions for future researchers are highlighted.

Keywords: analgesia, musculoskeletal pain, primary care, public involvement, shared decision making, systematic review

Background

The importance of patient and public involvement and engagement (PPIE) in health‐care research is recognized internationally.1, 2, 3, 4, 5 Patient and public involvement has been defined as ‘doing research ‘with’ or ‘by’ the public, rather than ‘to’, ‘about’ or ‘for’ the public’,6 and patient engagement as ‘where information and knowledge about research is provided and disseminated’.7 In addition to ethical and political arguments for the public having a voice in health‐care research, there is evidence that PPIE can impact on research questions, methods, dissemination of findings and engagement with local communities.4, 8, 9, 10, 11 Suggested positive effects of PPIE include prioritizing research topics, clarifying language in invitation letters, providing a wider perspective in data analysis and designing outcomes more relevant to patients.8, 11, 12 In the UK, PPIE is now integral to government‐funded health research, and a national advisory group, INVOLVE,7 provides guidance and examples of best practice for involving patients in health‐care research and for reporting patient involvement.11 Methods of implementing PPIE range from consultation, when researches seek the views of the public on key aspects of the research, to collaboration, an on‐going partnership throughout the research process, to publicly led research, in which lay people design and undertake the research.9 Current policy encourages PPIE using these different methods and within all research study designs.7, 13, 14

Systematic reviews ‘aim to identify, evaluate and summarize the findings of all relevant individual studies, thereby making the available evidence more accessible to decision makers' (Ref. 15, p5). Systematic reviews are the highest level of secondary research (which re‐examines the previously collected data15) investigating the effectiveness of health‐care interventions.16 As systematic reviews inform healthcare policy and guidance, PPIE in reviews is likely to have an important influence on healthcare delivery. Despite this, examples of patient involvement in systematic reviews remain rare and of varying detail and quality.17 Boote et al. describe a developing consensus of good practice for PPIE in health research 17, 18, 19 and best practice, and reporting guidelines have been developed.20, 21, 22 Our study aimed to integrate PPIE into a systematic review.

The review into which PPIE is integrated explores the factors affecting shared decision making around prescribing analgesia for musculoskeletal pain. Shared decision making (SDM) is the process whereby a health‐care professional and patient share information, and the patient is supported to consider management options.23 Musculoskeletal (MSK) pain includes both pain due to chronic conditions that have a specific diagnostic label such as osteoarthritis, and pain due to symptom labels such as ‘low back pain’ that may be chronic, episodic or acute in nature. MSK conditions remain one of the leading causes of disability worldwide,24 and half of those with an MSK condition feel that pain is the worst aspect of their condition.25 Many people with MSK pain take less than the therapeutic or prescribed dose of their analgesic,26, 27 and some have inadequate analgesia.28 Shared decision making within consultations may enable patients to be more active in prescribing decisions around their analgesic medications.29 This research aims to explore a collaborative approach to PPIE, in the context of a systematic review, by recognizing the particular expertise that patients have.30

Objective

To describe the process and impact of involving patients in a systematic review and narrative synthesis of shared decision making around prescribing analgesia for musculoskeletal pain in primary care consultations.

Method

To clarify the context of PPIE, the systematic review is briefly described. Methods of the systematic review are found in Box 1 and summary results in the results section in Box 2. The process of involving RUG members in the systematic review and how the changes made to the review were recorded are described below.

Box 1

Details of methods of the systematic review of factors affecting shared decision making around prescribing analgesia for musculoskeletal pain in primary care consultations

The search covered four broad topic areas, adapted from existing filters where possible for: primary care,31 musculoskeletal,32 shared decision making 33 and prescribing or analgesia.

Ten electronic databases were searched with follow‐up searches.

Key inclusion criteria were as follows: (i) primary care physicians and non‐pregnant adults (over 18 years old) with MSK pain; (ii) primary research studies focusing on consultations; (iii) sharing the decision of prescribing analgesia.

Outcomes of interest were factors that did or did not affect shared decision making around prescribing analgesia for musculoskeletal pain.

Quality of studies was assessed using existing criteria for quantitative and qualitative studies.34, 35 Studies were not excluded on the basis of quality, but methodological limitations informed the narrative synthesis. Results from full manuscripts were integrated into a narrative synthesis.36, 37

Box 2

Results of the systematic review of factors affecting shared decision making around prescribing analgesia for musculoskeletal pain in primary care consultations

Eight studies met the inclusion criteria (see Box 1 for details of inclusion criteria). Key messages suggested by the review were that (i) Patients' requests increase the likelihood of that medication being prescribed, and (ii) GPs attitude to the prescribing of opioid analgesics is controlling, due to legal and ethical concerns around prescribing opioids such as potential addiction.

Several other factors were investigated but the quality of the studies and strength of evidence was such that it was not possible to conclude whether those factors had an effect or not on SDM. For example, patient age and relationship with the GP may be important in SDM.

Thirty of the 39 factors identified by RUG members were absent in published studies included in the review (see Table S1, Additional Supplementary Information). Included studies did not investigate factors identified by RUG members in two categories of factors: ‘Emotion’ and ‘Condition’. Three factors from eight identified within the category ‘Impressions of the GP’ were found in the included studies: this was the most well investigated category.

Systematic review method

The systematic review addressed the question ‘What factors affect shared decision making around prescribing analgesia for musculoskeletal pain in primary care consultations?’ Further details of the methods of the review are below in Box 1, and the full protocol is available from the lead author.

Involving patients in the review process

Five members of an established patient research user group (RUG) collaborated with the researchers in the review process. RUG members of both genders, with a range of ages and musculoskeletal conditions, were recruited. Further information on the RUG and structure of support at the Research Institute has been reported in a case study.38

A RUG coordinator (RC) and a user support worker (USW) supported RUG members and liaised with the research team. The RUG support team were involved prior to preparation of the study protocol, giving advice on the suitability of the study for the RUG, agreeing aims and design, and providing written training material. The support team suggested having one of the support team and one researcher coordinate activities, as informed by their experience of different ways of working with researchers. The USW (Author AH) therefore acted as a point of contact for RUG members and facilitated meetings throughout the systematic review.

To inform the systematic review, the researchers and RUG support team planned workshops at three key points in the review process: when designing the protocol, interpreting the results and planning the dissemination. The workshops were planned by the researchers and reviewed by the RUG support team. Each three‐hour workshop included breaks and used a mixed format of presentation with discussion and small group techniques39 to ensure all RUG members could make a contribution. All authors agreed that having all three researchers in meetings with five RUG members would likely have been restrictive. Therefore, one researcher (Author CH) worked with the RUG members and support team throughout the systematic review process.

The first workshop explored RUG members' understanding of systematic reviews. RUG members were asked to discuss the research question and draw on their own experiences, share stories and describe key factors they thought were important to patients in sharing the decision of prescribing analgesia for musculoskeletal pain in primary care. At the second workshop, CH presented the preliminary results of the search and synthesis. RUG members were invited to critically discuss and plan how to share the results. At the final workshop, RUG members were asked to discuss and agree the final results of the systematic review and plans for further research and dissemination. After each workshop, notes were written up, checked by the USW and distributed to the RUG members with a comment sheet for them to return. RUG members were updated on the impact of their contribution via a newsletter and through discussion at each subsequent workshop. For all workshops, the RUG members were offered reimbursement for their time and travel as recommended as good practice for sustainable patient and public involvement in research.40, 41

Recording the impact of patient involvement

To record the impact of PPIE, the researchers documented how the review changed at each stage using a before and after technique. Prior to the workshops, researchers discussed and documented their viewpoints and preliminary decisions. In the workshops, RUG members' perspectives were discussed, and similarities and differences between these and researcher perspectives were debated. Following each workshop, CH liaised with the research team (Authors CCG and KD) to discuss the results and implications of the discussions and how these could affect the review. RUG members were updated about changes to the review and given opportunities to respond.

Results

Involving patients in the systematic review was feasible, and we successfully conducted three workshops with the RUG members. The aim, process and impact of the RUG members' involvement are summarized in Table 1. Impacts resulting from each workshop are described with specific details in the text below. Results of the systematic review itself are described in Box 2. Challenges and strategies for facilitating PPIE in systematic reviews are summarized in Table 2.

Table 1
Process and impact of the patient involvement in the systematic review of factors affecting shared decision making
Table 2
Challenges of involving PPIE in systematic reviews, strategies for facilitating involvement and suggestions for researchers

Workshop 1: Refining the scope of the review

The RUG members influenced the scope of the review by identifying factors that may affect SDM around prescribing analgesia for MSK pain, additional to those identified by the researchers. The researchers had highlighted factors potentially affecting SDM through preliminary literature searching and their clinical experience (CH and CCG). The researchers categorized these into ‘GP’ factors, ‘Consultation’ factors and ‘Patient’ factors. An example of a factor from the ‘GP’ category is that a GP's past experience of using a specific analgesic can influence SDM around prescribing that analgesic.

RUG members identified factors important to patients in sharing decisions about prescribing analgesia. They developed categories which were similar to the researchers, with additional categories of ‘Medication’ and ‘Emotion’. Rather than a category of ‘GP’ factors, patients discussed factors both of their ‘Impression of the GP’, such as the GP's ability to listen and explain, and their ‘Impression of external influences that affect the GP’, such as guidelines. The full list of 39 factors in seven categories identified by RUG members is available as supplementary information. The additional factors identified by the RUG members resulted in two changes to the review search strategy. The first change was that search terms for SDM were amended to reflect additional factors such as ‘Emotion’. The second change was that the researchers specifically looked for additional factors identified by RUG members in the full‐text studies included in the review.

Workshop 2: Interpreting the review findings

RUG members critiqued the provisional results of the review and identified limitations of the review literature. An example of RUG members' interpretation of the results is that RUG members were surprised at the poor representation of factors that they had identified. RUG members and researchers both identified a lack of SDM research in patient populations as a limitation in the existing literature. RUG members identified an additional limitation in the review literature that patients involved in studies may have felt uncomfortable raising concerns about their medical care, particularly if the researcher also had a clinical role.

The categories of factors identified by RUG members were used as a framework for the narrative synthesis and for reporting results. The patient perspective was integrated into the implications of the review by translating concerns RUG member raised into suggestions for further practice. For example, RUG members' surprise at the lack of studies of SDM with patient populations emphasized gaps in the literature for further study.

Workshop 3: dissemination of findings and reflections on engagement

Initial discussion of dissemination strategies focused on reaching patient audiences to empower patients when consulting a GP, to suggest medications that the patient had heard about or thought might be useful. RUG members discussed the finding that a patient suggesting medication to a GP increased the chance of that medication being prescribed, which may empower some patients. However, the RUG members raised concerns that patients suggesting medication to a GP may lead to conflict within the consultation. Therefore rather than aiming to disseminate findings with patients, we prioritized dissemination and engagement with GP audiences.

RUG members and the support team planned their own roles in engagement including reviewing abstracts, presentations and publications, attending and giving presentations and contributing the patient's perspective to discussions at conferences. Gaps in the literature identified in the review and factors identified by the RUG members informed a subsequent phase of research: a secondary analysis of digitally recorded GP consultations exploring how decisions are shared in practice. PPIE continued into this phase of the research.

Challenges of, and strategies facilitating, PPIE in systematic reviews

A number of challenges of involving PPIE in systematic reviews such as time pressures and managing power dynamics have been identified in a review of case examples.17 Strategies used by the researchers to manage these commonly identified challenges and suggestions from their experience of integrating current recommendations for good practice around PPIE in a systematic review are described in Table 2. Key strategies for addressing challenges included continuity with a PPIE lead in the PPIE support team and researcher team, and applying for specific funding to support PPIE time and resource requirements.

Discussion

This paper reports PPIE collaboration at three time‐points in a systematic review and reflects on the impact on the review. Altering the search strategy to reflect additional factors identified by PPIE members highlighted gaps in the published literature around issues important to patients which would have otherwise gone unreported. PPIE throughout the review ensured that the patient's perspective was integrated into the protocol design, interpretation of the results and planning and prioritizing dissemination.

This study applied previous research on good practices for PPIE in health‐care research18, 19, 20, 22 and in systematic reviews.17, 21 We used case examples described by Boote et al.17 to anticipate and report common challenges in PPIE. We found that the work by Boote et al.17 provided a comprehensive framework for the challenges we faced. Placing the patients' perspective alongside the scientific paradigm can increase ‘credibility’ with a multilayered understanding in research.43 Concerns that PPIE could be a source of research bias have been described.9 This study demonstrates how the patients' perspectives both agreed with and differed from the researchers' perspectives. Two approaches towards PPIE in this study address concerns of bias. Firstly, clear description of the review before and after each time‐point at which PPIE occurred so that the influence of PPIE was recorded and reported clearly. A second approach is linking aims of PPIE with the process and impact of PPIE so that the intention, application and influence of PPIE in the research is apparent. These transparent approaches to PPIE may prove useful for further enquiry into the impact of PPIE on research.

PPIE has been performed in several other systematic reviews in a health‐care context, but details of impact of PPIE on systematic reviews are described in separate reports8, 44, 45 rather than in the reviews themselves.46, 47, 48 It has been suggested that the structure of reviews change so that the process and impact of PPIE are routinely reported.8 This paper provides an example for reporting PPIE within a systematic review, and the PIRICOM report is a further illustration.8

Previous research has reported PPIE in dissemination through patient‐focused publications and the popular media in addition to traditional conferences.44, 48 Our study is to our knowledge the first to report the PPIE in prioritizing dissemination and engagement activities in a systematic review within health care. Involving patients in prioritizing the dissemination and engagement plan resulted in early identification of challenges in implementing findings from the review with patient audiences.

Strengths and limitations

Strengths and limitations of the study are focused around two issues, the ‘representativeness’ of PPIE and the extent of PPIE integration within the review. How well those involved in PPIE ‘represent’ the wider community is a recognized tension.9, 49 Lay experience is ‘located within personal history and narrative logic’ and contains a ‘diversity of world views’[43 p513]. In order to capture this diversity, both who is involved and how they are involved influences the representativeness. Strengths of the PPIE representativeness in this study are that RUG members with different research and condition experiences were involved, supported by a team and working with one researcher. These RUG members could therefore potentially voice a wider range of experiences than individuals who are very well integrated into the research community. Secondly, the researchers used strategies throughout to facilitate sharing the experiences and narratives from all RUG members. Limitations in representativeness are that the RUG members had similar white British ethnicity and were all over the age of 45 years. Different groups such as carers or stakeholder organizations10 were not involved and including individuals from different populations and roles may have yielded differing factors and priorities. However, the factors RUG members identified were similar in number and scope to those identified in a systematic review of patient reported barriers and facilitators to SDM in health‐care consultations.50 This suggests that the RUG members identified factors that were broadly relevant to patients.

The extent of PPIE integration into the review process also raises strengths and limitations of the study. It is a strength of the study that PPIE occurred at the early stage of question development, and continued throughout the review process. Having one of the PPIE support team and one researcher acting as points of contact is a strength as it facilitated clear communication and clarity of roles. Tokenistic PPIE in health‐care research is a concern,12 and in this study, we aimed to truly value PPIE and took practical steps to manage challenges of PPIE and facilitate involvement throughout (see Table 2). However, lack of understanding of how PPIE members themselves felt about the extent of their integration into the study is a limitation. Although members did not drop out between workshops, which has been discussed as proxy for PPIE satisfaction,51 there was no evaluation of the experience of the PPIE members themselves and this highlights a gap in methods and tools for understanding PPIE member experiences.

Recommendations

Future research exploring PPIE should use best practice guidelines and our recommendations when planning, implementing, evaluating and reporting PPIE in systematic reviews. This approach will enable researchers to build on what is already known in this area, anticipate and manage expected challenges, and document the impact of PPIE clearly. It will also facilitate comparison and synthesis of PPIE across reviews. The impact of PPIE reported in this study is on the systematic review itself. Further work remains to be done on evaluating the impact of involvement in reviews on PPIE members themselves.

Conclusions

PPIE collaboration refined the scope of this systematic review and influenced interpretation and dissemination of the findings. Gaps in published literature important to patients were highlighted and the systematic review and its dissemination more clearly reflected patient priorities. PPIE in this systematic review built on existing good practice guidance and examples in design, implementation and reporting. Future researchers may draw on strategies discussed to integrate good practice into their work, including transparent description of PPIE impact and describing how common PPIE challenges are managed. As researchers respond to policy imperatives to integrate PPIE into their research, PPIE in systematic reviews should utilize best practice as described so that patient perspectives and priorities are clearly represented.

Supporting information

Table S1. Table of factors identifed by RUG members and systematic review which affect shared decision making around prescribing analgesia for musculoskeletal pain in primary care consultations.

Acknowledgements

Carol Rhodes, RUG coordinator and Adele Higginbottom, user support worker, for arranging, administering and facilitating patient workshops and reviewing abstracts and conference presentations.

Patient Research User Group members including Steven Tatton, Teresa George, Robert Taylor and Sheila Hickson for sharing their experiences, expertise and time.

This report is an independent research arising from an In‐Practice Fellowship (NIHR‐IPF‐2013‐07‐09) awarded to Catherine Hyde by the National Institute for Health Research. The PPIE in the systematic review was funded by the Scientific Foundation board of the Royal College of General Practitioners (Grant number SFB 2014‐01). CCG is supported by the National Institute for Health Research (NIHR) Collaborations for Leadership in Applied Health Research and Care West Midlands. KD was funded by the Wellcome Trust (083572). The views expressed in this research are those of the authors and not necessarily those of the NHS, the National Institute for Health Research or the Department of Health.

References

1. National Health and Medical Research Council . Statement on Consumer and Community Participation in Health and Medical Research. Canberra, ACT: National Health and Medical Research Council, 2001.
2. Canadian Institutes of Health Research . Guidelines for Health Research Involving Aboriginal People. Ottawa, ON: Canadian Institutes of Health Research, 2007.
3. Caron‐Flinterman JF, Broerse JEW, Teerling J et al Stakeholder participation in health research agenda setting: the case of asthma and COPD research in the Netherlands. Science and Public Policy, 2006; 33: 291–304.
4. Oliver S, Clarke‐Jones L, Rees R et al Involving consumers in research and development agenda setting for the NHS: developing an evidence‐based approach. Health Technology Assessment, 2004; 8: 1–148. [PubMed]
5. World Health Organisation . The Tallinn Charter: Health Systems for Health and Wealth. Copenhagen: World Health organisation, 2009.
6. INVOLVE . What is Public Involvement in Research? Eastleigh: INVOLVE; http://www.invo.org.uk/find-out-more/what-is-public-involvement-in-research-2/, accessed 13 Apr 2015.
7. INVOLVE . Going the Extra Mile: Improving the Nation's Health and Wellbeing Through Public Involvement in Research. London: INVOLVE, 2014.
8. Brett J, Staniszewska S, Mockford C et al The PIRICOM Study: A Systematic Review of the Conceptualisation, Measurement, Impact and Outcomes of Patients and Public Involvement in Health and Social Care Research. London: Royal College of Nursing, UK Clinical Research Collaboration & Warwick University, 2010.
9. Boote J, Telford R, Cooper C. Consumer involvement in health research: a review and research agenda. Health Policy, 2002; 61: 213–236. [PubMed]
10. Entwistle VA, Renfrew MJ, Yearley S, Forrester J, Lamont T. Lay perspectives: advantages for health research. British Medical Journal, 1998; 316: 463–466. [PubMed]
11. Staley K. Exploring Impact: Public Involvement in NHS, Public Health and Social Care Research. Eastleigh: INVOLVE, 2009.
12. Domecq JP, Prutsky G, Elraiyah T et al Patient engagement in research: a systematic review. BMC Health Services Research, 2014; 14: 89. [PubMed]
13. Research Council UK . Concordat for Engaging the Public with Research. London: Research Council UK, 2010.
14. Kings College London, Digital Science . The Nature, Scale and Beneficiaries of Research Impact: An Initial Analysis of Research Excellence Framework (REF) 2014 Impact Case Studies. London: Kings College London, Digital Science, 2015.
15. Centre for Reviews and Dissemination . Systematic Reviews: CRD's Guidance for Undertaking Reviews in Health Care. York: University of York, 2009.
16. Evans D. Hierarchy of evidence: a framework for ranking evidence evaluating healthcare interventions. Journal Clinical Nursing, 2003; 12: 77–84. [PubMed]
17. Boote J, Baird W, Sutton A. Public involvement in the systematic review process in health and social care: a narrative review of case examples. Health Policy, 2011; 102: 105–116. [PubMed]
18. Telford R, Boote JD, Cooper CL. What does it mean to involve consumers successfully in NHS research? A consensus study Health Expectations, 2004; 7: 209–220. [PubMed]
19. Boote J, Barber R, Cooper C. Principles and indicators of successful consumer involvement in NHS research: results of a Delphi study and subgroup analysis. Health Policy, 2006; 75: 280–297. [PubMed]
20. Popay J, Collins M, (editors) with the PiiAF Study Group. The Public Involvement Impact Assessment Framework Guidance. Universities of Lancaster, Liverpool and Exeter, 2014.
21. INVOLVE . Public Involvement in Systematic Reviews: Supplement to the Briefing Notes for Researchers. Eastleigh: INVOLVE, 2012.
22. Staniszewska S, Brett J, Mockford C, Barber R. The GRIPP checklist: strengthening the quality of patient and public involvement reporting in research. International Journal of Technology Assessment in Health Care, 2011; 27: 391–399. [PubMed]
23. Elwyn G, Frosch D, Thomson R et al Shared decision making: a model for clinical practice. Journal of General Internal Medicine, 2012; 27: 1361–1367. [PubMed]
24. Vos T, Flaxman AD, Naghavi M et al Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990—2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet, 2012; 380: 2163–2196. [PubMed]
25. Siegle G, Ingram R. Arthritis: the big picture. Contemporary Psychology APA Review of Books, 1996; 41: 163–164.
26. Chang Y‐P, Wray LO, Sessanna L, Peng H‐L. Use of prescription opioid medication among community‐dwelling older adults with noncancer chronic pain. Journal of Addictions Nursing, 2011; 22: 19–24.
27. Fourrier‐Reglat A, Cuong HM, Lassalle R et al Concordance between prescriber‐ and patient‐reported previous medical history and NSAID indication in the CADEUS cohort. Pharmacoepidemiology Drug Safety, 2010; 19: 474–481. [PubMed]
28. Manias E, Claydon‐Platt K, McColl GJ, Bucknall TK, Brand CA. Managing complex medication regimens: perspectives of consumers with osteoarthritis and healthcare professionals. Annals of Pharmacotherapy, 2007; 41: 764–771. [PubMed]
29. Stevenson F, Cox K, Britten N, Dundar Y. A systematic review of the research on communication between patients and health care professionals about medicines: the consequences for concordance. Health Expectations, 2004; 7: 235–245. [PubMed]
30. Gibson A, Britten N, Lynch J. Theoretical directions for an emancipatory concept of patient and public involvement. Health, 2012; 16: 531–547. [PubMed]
31. Jones M, Rait G, Falconer J, Feder G. Systematic review: prognosis of angina in primary care. Family Practice, 2006; 23: 520–528. [PubMed]
32. Jordan JL, Holden MA, Mason EE, Foster N. Interventions to improve adherence to exercise for chronic musculoskeletal pain in adults. The Cochrane Database of Systematic Reviews, 2010; 1: CD005956. [PubMed]
33. Légaré F, Ratté S, Stacey D et al Interventions for Improving the Adoption of Shared Decision Making by Healthcare Professionals. London: The Cochrane Collaboration, 2010. [PubMed]
34. Critical Appraisal Skills Programme . Qualitative Research Checklist. Oxford: Critical Appriasial Skills Programme, 2013.
35. Critical Appraisal Skills Programme . Control Study Checklist. Oxford: Critical Appriasial Skills Programme, 2013.
36. Dixon‐Woods M, Agarwal S, Jones D, Young B, Sutton A. Synthesising qualitative and quantitative evidence: a review of possible methods. Journal of Health Services Research & Policy, 2005; 10: 45–53. [PubMed]
37. Popay J, Roberts H, Petticrew M, Roen K, Duffy S. Guidance on the Conduct of Narrative Synthesis in Systematic Reviews. Lancaster University: A Product of the ESRC Methods Programme, 2006.
38. Jinks C, Carter P, Rhodes C, Beech R, Dziedzic K. Sustaining patient and public involvement in research: a case study of a research centre. Journal of Care Services Management, 2015; 7: 146–154. [PMC free article] [PubMed]
39. Walton H. Small group methods in medical teaching. Medical Education, 1997; 31: 459–464. [PubMed]
40. Mental Health Research Network and INVOLVE . Budgeting for Involvement: Practical Advice on Budgeting for Actively Involving the Public in Research Studies. London: Ensleigh, 2013.
41. Staniszewska S, Jones N, Newburn M, Marshall S. User involvement in the development of a research bid: barriers, enablers and impacts. Health Expectations, 2007; 10: 173–183. [PubMed]
42. National Research Ethics Service (NRES) and INVOLVE . Patient and Public Involvement in Research and Research Ethics Committee Review. London: National Research Ethics Service and INVOLVE, 2009.
43. Ong BN. The lay perspective in health technology assessment. International Journal of Technology Assessment in Health Care, 1996; 12: 511–517. [PubMed]
44. Stewart R, Hargreaves K, Oliver S. Evidence informed policy making for health communication. Health Education Journal, 2005; 64: 120–128.
45. (SURE) Service User Research Enterprise, Institute of Psychiatry . Review of Consumers' Perspectives on Electro‐Convulsive Therapy. London: Service User Research Enterprise & Institute of Psychiatry, 2002.
46. Mockford C, Staniszewska S, Griffiths F, Herron‐marx S. The impact of patient and public involvement on UK NHS health care: a systematic review. International Journal for Quality in Health Care, 2012; 24: 28–38. [PubMed]
47. Rose D, Fleischmann P, Wykes T, Leese M, Bindman J. Patients' perspectives on electroconvulsive therapy: systematic review. British Medical Journal, 2003; 326: 1363–1368. [PubMed]
48. Carr S, Fleischmann P, Rees R, Oliver S. Collection of Examples of Service User and Carer Participation in Systematic Reviews. London: Social Care Institute for Excellence, 2007.
49. Smith E, Donovan S, Beresford P et al Getting ready for user involvement in a systematic review. Health Expectations, 2009; 12: 197–208. [PubMed]
50. Joseph‐Williams N, Elwyn G, Edwards A. Knowledge is not power for patients: a systematic review and thematic synthesis of patient‐reported barriers and facilitators to shared decision making. Patient Education and Counselling, 2014; 94: 291–309. [PubMed]
51. Stocks SJ, Giles SJ, Cheraghi‐Sohi S, Campbell SM. Application of a tool for the evaluation of public and patient involvement in research. British Medical Journal Open, 2015; 5: e006390. [PMC free article] [PubMed]

Articles from Health Expectations : An International Journal of Public Participation in Health Care and Health Policy are provided here courtesy of Wiley-Blackwell