Search tips
Search criteria 


Logo of intmedInternal Medicine
Intern Med. 2017 January 15; 56(2): 231–232.
PMCID: PMC5337474

Isolated Bilateral Coronary Ostial Stenosis in Behçet's Disease

We herein report the case of a 67-year-old woman with isolated bilateral coronary ostial stenosis in Behçet's disease (BD). She was diagnosed BD 10 years previously, and steroids had been administered as treatment. Her coronary risk factors were hypertension and dyslipidemia, and she presented with recent onset angina. Computed tomography coronary angiography showed severe calcification of the bilateral coronary ostia (Picture 1). Other imaging modalities showed no aorto-ostial lesions. Coronary angiography showed intermediate ostial stenosis of the right coronary artery and severe stenosis of the left main coronary artery (Picture 2). Based on the fractional flow reserve values (right coronary artery: 0.85, left anterior descending artery: 0.68, and left circumflex artery: 0.75), she underwent coronary bypass surgery. Although BD is a systemic inflammatory disease that can affect all types and sizes of blood vessels, coronary involvement is rare (1,2).

The authors state that they have no Conflict of Interest (COI).


1. Fei Y, Li X, Lin S, et al. Major vascular involvement in Behcet's disease: A retrospective study of 796 patients. Clin Rheumatol 32: 845-852, 2013. [PubMed]
2. Arishiro K, Nariyama J, Hoshiga M, et al. Vascular Behçet's disease with coronary artery aneurysm. Intern Med 45: 903-907, 2006. [PubMed]

Articles from Internal Medicine are provided here courtesy of Japanese Society of Internal Medicine