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Logo of jbcThe Journal of Biological Chemistry
J Biol Chem. 2017 February 3; 292(5): 2049.
PMCID: PMC5290976

Prothymosin-α mediates nuclear import of the INrf2/Cul3·Rbx1 complex to degrade nuclear Nrf2.

VOLUME 284 (2009) PAGES 13856–13868

This article has been retracted by the publisher. An investigation at the University of Maryland, Baltimore determined that there is evidence of duplication in Fig. 2B. The investigation also determined that in Fig. 3, data in Cul3, INrf2, and Rbx1 show clear evidence of manipulations in which individual blots were spliced and rearranged. In Fig. 5A, duplication of bands is apparent. In addition, the journal determined that in Fig. 1B, left panel, lanes 6 and 9 were duplicated. The Lamin B immunoblot from Fig. 5D was reused as Lamin B in Fig. 5E. Also in Fig. 5E, the INrf2 immunoblot from 25 nm and 50 nm PTMα siRNA were duplicated. In Fig. 9B, lanes 5 and 6 of the PTMα immunoblot were duplicated.

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