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Nucleic Acids Res. 1994 April 11; 22(7): 1125–1127.
PMCID: PMC523631

Protein splicing elements: inteins and exteins--a definition of terms and recommended nomenclature.

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Selected References

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  • Dujon B, Belfort M, Butow RA, Jacq C, Lemieux C, Perlman PS, Vogt VM. Mobile introns: definition of terms and recommended nomenclature. Gene. 1989 Oct 15;82(1):115–118. [PubMed]
  • Davis EO, Thangaraj HS, Brooks PC, Colston MJ. Evidence of selection for protein introns in the recAs of pathogenic mycobacteria. EMBO J. 1994 Feb 1;13(3):699–703. [PubMed]
  • Bremer MC, Gimble FS, Thorner J, Smith CL. VDE endonuclease cleaves Saccharomyces cerevisiae genomic DNA at a single site: physical mapping of the VMA1 gene. Nucleic Acids Res. 1992 Oct 25;20(20):5484–5484. [PMC free article] [PubMed]
  • Cooper AA, Chen YJ, Lindorfer MA, Stevens TH. Protein splicing of the yeast TFP1 intervening protein sequence: a model for self-excision. EMBO J. 1993 Jun;12(6):2575–2583. [PubMed]
  • Davis EO, Sedgwick SG, Colston MJ. Novel structure of the recA locus of Mycobacterium tuberculosis implies processing of the gene product. J Bacteriol. 1991 Sep;173(18):5653–5662. [PMC free article] [PubMed]
  • Davis EO, Jenner PJ, Brooks PC, Colston MJ, Sedgwick SG. Protein splicing in the maturation of M. tuberculosis recA protein: a mechanism for tolerating a novel class of intervening sequence. Cell. 1992 Oct 16;71(2):201–210. [PubMed]
  • Gimble FS, Thorner J. Homing of a DNA endonuclease gene by meiotic gene conversion in Saccharomyces cerevisiae. Nature. 1992 May 28;357(6376):301–306. [PubMed]
  • Gimble FS, Thorner J. Purification and characterization of VDE, a site-specific endonuclease from the yeast Saccharomyces cerevisiae. J Biol Chem. 1993 Oct 15;268(29):21844–21853. [PubMed]
  • Gu HH, Xu J, Gallagher M, Dean GE. Peptide splicing in the vacuolar ATPase subunit A from Candida tropicalis. J Biol Chem. 1993 Apr 5;268(10):7372–7381. [PubMed]
  • Hirata R, Ohsumk Y, Nakano A, Kawasaki H, Suzuki K, Anraku Y. Molecular structure of a gene, VMA1, encoding the catalytic subunit of H(+)-translocating adenosine triphosphatase from vacuolar membranes of Saccharomyces cerevisiae. J Biol Chem. 1990 Apr 25;265(12):6726–6733. [PubMed]
  • Hirata R, Anraku Y. Mutations at the putative junction sites of the yeast VMA1 protein, the catalytic subunit of the vacuolar membrane H(+)-ATPase, inhibit its processing by protein splicing. Biochem Biophys Res Commun. 1992 Oct 15;188(1):40–47. [PubMed]
  • Hodges RA, Perler FB, Noren CJ, Jack WE. Protein splicing removes intervening sequences in an archaea DNA polymerase. Nucleic Acids Res. 1992 Dec 11;20(23):6153–6157. [PMC free article] [PubMed]
  • Kane PM, Yamashiro CT, Wolczyk DF, Neff N, Goebl M, Stevens TH. Protein splicing converts the yeast TFP1 gene product to the 69-kD subunit of the vacuolar H(+)-adenosine triphosphatase. Science. 1990 Nov 2;250(4981):651–657. [PubMed]
  • Perler FB, Comb DG, Jack WE, Moran LS, Qiang B, Kucera RB, Benner J, Slatko BE, Nwankwo DO, Hempstead SK, et al. Intervening sequences in an Archaea DNA polymerase gene. Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5577–5581. [PubMed]
  • Xu MQ, Southworth MW, Mersha FB, Hornstra LJ, Perler FB. In vitro protein splicing of purified precursor and the identification of a branched intermediate. Cell. 1993 Dec 31;75(7):1371–1377. [PubMed]
  • Doolittle WF, Stoltzfus A. Molecular evolution. Genes-in-pieces revisited. Nature. 1993 Feb 4;361(6411):403–403. [PubMed]
  • Doolittle RF. The comings and goings of homing endonucleases and mobile introns. Proc Natl Acad Sci U S A. 1993 Jun 15;90(12):5379–5381. [PubMed]
  • Hendrix RW. Protein carpentry. Curr Biol. 1991 Apr;1(2):71–73. [PubMed]
  • Shub DA, Goodrich-Blair H. Protein introns: a new home for endonucleases. Cell. 1992 Oct 16;71(2):183–186. [PubMed]
  • Wallace CJ. The curious case of protein splicing: mechanistic insights suggested by protein semisynthesis. Protein Sci. 1993 May;2(5):697–705. [PubMed]
  • Lambowitz AM, Belfort M. Introns as mobile genetic elements. Annu Rev Biochem. 1993;62:587–622. [PubMed]

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