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Logo of jclinpathJournal of Clinical PathologyVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
J Clin Pathol. 1995 January; 48(1): 59–60.
PMCID: PMC502264

Pathologist variation in reporting cervical borderline epithelial abnormalities and cervical intraepithelial neoplasia.


AIMS--To evaluate the interobserver variation in the diagnosis of cervical intraepithelial lesions, including the new category "borderline abnormalities of uncertain significance" (BAUS) which has not been tested before. METHODS--Biopsy specimens of 122 patients were reviewed by five histopathologists and the diagnoses subjected to kappa statistical analysis. RESULTS--There was poor interobserver agreement in all categories, particularly between BAUS and normal tissue. CONCLUSIONS--The current guidelines for the histological diagnosis of cervical intraepithelial neoplasia and BAUS are poorly reproducible.

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