PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jclinpathJournal of Clinical PathologyVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
 
J Clin Pathol. 1982 August; 35(8): 824–829.
PMCID: PMC497797

Angiodysplasias of the colon.

Abstract

We studied 14 large bowel resections from patients with a provisional clinical diagnosis of a bleeding vascular lesion of the colon. For the purpose of this study we developed a barium-gelatine vascular injection technique. Six of the 14 cases were proven to be angiodysplasias with an identifiable mucosal vascular ectasia. The pathological findings in these six cases are described. We conclude that angiodysplasia represent a significant cause of lower gastrointestinal haemorrhage in the elderly. It is our opinion that only the mucosa vascular ectasia seen in these cases is histologically diagnostic and that sub-mucosal venous ectasia, while characteristic of angiodysplasia, is non-specific. the differential diagnostic features which will allow the histological distinction of angiodysplasia from other vascular lesions of the colon are discussed.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.5M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Athanasoulis CA, Galdabini JJ, Waltman AC, Novelline RA, Greenfield AJ, Ezpeleta ML. Angiodysplasia of the colon: a cause of rectal bleeding. Cardiovasc Radiol. 1977;1(1):3–13. [PubMed]
  • Boley SJ, Sammartano R, Adams A, DiBiase A, Kleinhaus S, Sprayregen S. On the nature and etiology of vascular ectasias of the colon. Degenerative lesions of aging. Gastroenterology. 1977 Apr;72(4 Pt 1):650–660. [PubMed]
  • Welch CE, Athanasoulis CA, Galdabini JJ. Hemorrhage from the large bowel with special reference to angiodysplasia and diverticular disease. World J Surg. 1978 Jan;2(1):73–83. [PubMed]
  • Moore JD, Thompson NW, Appelman HD, Foley D. Arteriovenous malformations of the gastrointestinal tract. Arch Surg. 1976 Apr;111(4):381–389. [PubMed]
  • Baer JW, Ryan S. Analysis of cecal vasculature in the search for vascular malformations. AJR Am J Roentgenol. 1976 Feb;126(2):394–405. [PubMed]
  • Galloway SJ, Casarella WJ, Shimkin PM. Vascular malformations of the right colon as a cause of bleeding in patients with aortic stenosis. Radiology. 1974 Oct;113(1):11–15. [PubMed]
  • Love JW, Jahnke EJ, Zacharias D, Davidson WA, Kidder WR, Luan LL. Calcific aortic stenosis and gastrointestinal bleeding. N Engl J Med. 1980 Apr 24;302(17):968–968. [PubMed]
  • Mitsudo SM, Boley SJ, Brandt LJ, Montefusco CM, Sammartano RJ. Vascular ectasias of the right colon in the elderly: a distinct pathologic entity. Hum Pathol. 1979 Sep;10(5):585–600. [PubMed]
  • Tarin D, Allison DJ, Modlin IM, Neale G. Diagnosis and management of obscure gastrointestinal bleeding. Br Med J. 1978 Sep 9;2(6139):751–754. [PMC free article] [PubMed]
  • Lewi HJ, Gledhill T, Gilmour HM, Buist TA. Arteriovenous malformations of the intestine. Surg Gynecol Obstet. 1979 Nov;149(5):712–716. [PubMed]
  • GRIFFITHS JD. Extramural and intramural blood-supply of colon. Br Med J. 1961 Feb 4;1(5222):323–326. [PMC free article] [PubMed]
  • Abrahamson J, Shandling B. Intestinal hemangiomata in childhood and a syndrome for diagnosis: a collective review. J Pediatr Surg. 1973 Aug;8(4):487–495. [PubMed]
  • BIRD RM, JAQUES WE. Vascular lesion of hereditary hemorrhagic telangiectasia. N Engl J Med. 1959 Mar 19;260(12):597–599. [PubMed]
  • Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1974. N Engl J Med. 1974 Sep 12;291(11):569–575. [PubMed]
  • Baker AL, Kahn PC, Binder SC, Patterson JF. Gastrointestinal bleeding due to blue rubber bleb nevus syndrome syndrome. A case diagnosed by angiography. Gastroenterology. 1971 Oct;61(4):530–534. [PubMed]
  • Shaff MI, Sacks I, Stein D, Horner J, Louw JH. Caecal angiodysplasia as a cause of chronic iron deficiency anaemia: a case report. S Afr Med J. 1980 Jan 5;57(1):17–20. [PubMed]

Articles from Journal of Clinical Pathology are provided here courtesy of BMJ Publishing Group