PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of jnnpsycJournal of Neurology, Neurosurgery and PsychiatryVisit this articleSubmit a manuscriptReceive email alertsContact usBMJ
 
J Neurol Neurosurg Psychiatry. 1974 April; 37(4): 422–426.
PMCID: PMC494673

Comparative trial of benzhexol, amantadine, and levodopa in the treatment of Parkinson's disease

Abstract

Fourteen slightly disabled patients with Parkinsonism were treated separately with benzhexol, amantadine, and levodopa. Benzhexol and amantadine both gave a 15% reduction in functional disability and levodopa a 36% reduction. Benzhexol lessened the rigidity and improved the flexion of posture of Parkinson's disease, but had little or no effect on akinesia and tremor. Amantadine and levodopa caused improvement in all these symptoms. The combination of benzhexol and amantadine was as effective after four weeks of treatment as levodopa was after six months.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (658K), or click on a page image below to browse page by page.

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Group