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Logo of jbcThe Journal of Biological Chemistry
 
J Biol Chem. 2016 July 1; 291(27): 14392.
PMCID: PMC4933197

Myostatin induces insulin resistance via Casitas B-lineage lymphoma b (Cblb)-mediated degradation of insulin receptor substrate 1 (IRS1) in response to high calorie diet intake.

VOLUME 289 (2014) PAGES 7654–7670

This article has been withdrawn by the authors. In this article, we reported a mechanism through which myostatin induces insulin resistance. After a thorough investigation by the Nanyang Technological University in Singapore, data falsifications were found in some of the in vitro laboratory studies, which invalidate the results reported. Thus, the co-authors wish to withdraw this publication and offer our sincere apologies to all those investigators who may have been affected and misled by this.


Articles from The Journal of Biological Chemistry are provided here courtesy of American Society for Biochemistry and Molecular Biology