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Logo of mjafiGuide for AuthorsAbout this journalExplore this journalMedical Journal, Armed Forces India
Med J Armed Forces India. 2006 January; 62(1): 96.
Published online 2011 July 21. doi:  10.1016/S0377-1237(06)80192-9
PMCID: PMC4923283

Salmonella Typhi: A Changing Sensitivity Pattern: Reply

  • 1.
    I thank the reader for going through the article carefully and making valuable observations.
  • 2.
    After careful epidemiological investigation and pin pointing source, the epidemic could be contained.
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    Multi-drug Resistance (MDR) strains were seen during the epidemic. As there was a single source, it was possibly a single plasmid containing strain of same phage type. However during subsequent period i.e. 2003-2005 in this hospital MDR strains were not isolated. During 2003, out of 32 isolates of salmonella only 13 isolates showed single drug resistance (4 to chloramphenicol, 9 to Ampicillin). During 2004 there were 97 isolates of salmonella out of which 16 showed resistance to single drug (chloramphenicol – 4, Ampicillin – 9, and cotrimoxazole – 3). Till June 2005, 23 salmonella were isolated and all are sensitive to primary drugs. This definitely shows a improvement in trend and chloramphenicol is again emerging as a drug of choice for enteric fever.

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