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Heart. 1996 December; 76(6): 550–552.
PMCID: PMC484612

Treatment of ventricular tachycardia-induced cardiomyopathy by transcatheter radiofrequency ablation.


Catheter ablation of ventricular tachycardia was successfully performed in a patient with dilated cardiomyopathy (ejection fraction 38%) and a long history of repetitive palpitations. Holter monitoring showed ventricular tachycardia that had a left bundle branch block QRS configuration with inferior axis deviation and was present for about one third of the daytime hours. At electrophysiological testing, ventricular tachycardia was reproduced by isoprenaline infusion. Radiofrequency energy delivered to the right ventricular outflow tract was successful at preventing the induction of ventricular tachycardia. Left ventricular ejection fraction had improved from 38% to 48% one month after ablation. During the follow up period of one year the patient remained free from arrhythmia on no medication. The ejection fraction was 61% one year after ablation. This report confirms that dilated cardiomyopathy can be induced by ventricular tachycardia and demonstrates that dilated cardiomyopathy can be reversed if the tachycardia is abolished by radiofrequency catheter ablation.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Packer DL, Bardy GH, Worley SJ, Smith MS, Cobb FR, Coleman RE, Gallagher JJ, German LD. Tachycardia-induced cardiomyopathy: a reversible form of left ventricular dysfunction. Am J Cardiol. 1986 Mar 1;57(8):563–570. [PubMed]
  • Cruz FE, Cheriex EC, Smeets JL, Atié J, Peres AK, Penn OC, Brugada P, Wellens HJ. Reversibility of tachycardia-induced cardiomyopathy after cure of incessant supraventricular tachycardia. J Am Coll Cardiol. 1990 Sep;16(3):739–744. [PubMed]
  • Williams RE, Kass DA, Kawagoe Y, Pak P, Tunin RS, Shah R, Hwang A, Feldman AM. Endomyocardial gene expression during development of pacing tachycardia-induced heart failure in the dog. Circ Res. 1994 Oct;75(4):615–623. [PubMed]
  • Fyfe DA, Gillette PC, Crawford FA, Jr, Kline CH. Resolution of dilated cardiomyopathy after surgical ablation of ventricular tachycardia in a child. J Am Coll Cardiol. 1987 Jan;9(1):231–234. [PubMed]
  • Matsuura Y, Chin W, Kurihara T, Yasui K, Asao M, Hayashi T, Fukushima M, Abe H, Kurata A. [Tachycardia-induced cardiomyopathy: a case report]. J Cardiol. 1990;20(2):509–518. [PubMed]
  • Wen MS, Yeh SJ, Wang CC, Lin FC, Chen IC, Wu D. Radiofrequency ablation therapy in idiopathic left ventricular tachycardia with no obvious structural heart disease. Circulation. 1994 Apr;89(4):1690–1696. [PubMed]

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