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Heart. Dec 1996; 76(6): 548–549.
PMCID: PMC484611
Isomerism of the atrial appendages associated with 22q11 deletion in a fetus.
R. W. Yates, F. L. Raymond, A. Cook, and G. K. Sharland
Department of Fetal Cardiology, Guy's Hospital, London.
Abstract
There is a strong association between prenatally diagnosed structural heart disease and fetal chromosomal abnormalities. Isomerism of the atrial appendages is an exception to this because the fetal karyotype is usually normal in this condition. A case of atrial isomerism diagnosed antenatally with a normal female karyotype but with a microdeletion of chromosome 22q11 is reported.
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