Search tips
Search criteria 


Logo of brheartjLink to Publisher's site
Br Heart J. 1995 December; 74(6): 700–701.
PMCID: PMC484140

Severe coronary vasospasm associated with hyperthyroidism causing myocardial infarction.


A 48 year old woman presented with angina after an anterior myocardial infarction and was found to be hyperthyroid. Coronary angiography showed a stenosis of the left coronary os and a long, severe stenosis of the left anterior descending artery which was partially relieved by glyceryl trinitrate. Three months later, after radioactive iodine treatment had rendered her euthyroid, repeat coronary angiography showed entirely normal coronary arteries. This unusual case establishes an association between hyperthyroidism and coronary vasospasm resulting in myocardial infarction.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1020K), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • SOMERVILLE W, LEVINE SA. Angina pectoris and thyrotoxicosis. Br Heart J. 1950 Jul;12(3):245–257. [PMC free article] [PubMed]
  • Kotler MN, Michaelides KM, Bouchard RJ, Warbasse JR. Myocardial infarction associated with thyrotoxicosis. Arch Intern Med. 1973 Nov;132(5):723–728. [PubMed]
  • Resnekov L, Falicov RE. Thyrotoxicosis and lactate-producing angina pectoris with normal coronary arteries. Br Heart J. 1977 Oct;39(10):1051–1057. [PMC free article] [PubMed]
  • Moliterno D, DeBold CR, Robertson RM. Case report: coronary vasospasm--relation to the hyperthyroid state. Am J Med Sci. 1992 Jul;304(1):38–42. [PubMed]
  • Wei JY, Genecin A, Greene HL, Achuff SC. Coronary spasm with ventricular fibrillation during thyrotoxicosis: response to attaining euthyroid state. Am J Cardiol. 1979 Feb;43(2):335–339. [PubMed]
  • Nakano T, Konishi T, Takezawa H. Vasospastic angina in thyrotoxicosis--case reports. Angiology. 1987 Sep;38(9):717–722. [PubMed]
  • Papazoglou N, Kelermenos N, Andriopoulos J, Prionas D. Vasospastic angina with hyperthyroidism. Heart Lung. 1987 Jul;16(4):437–438. [PubMed]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group