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Br Heart J. 1975 November; 37(11): 1195–1197.
PMCID: PMC482939

A case of prosthetic valve endocarditis caused by Corynebacterium hofmanni and Candida albicans.


The case is described of a 49-year-old woman who developed endocarditis in relation to the prosthetic valve two months after insertion of a Starr-Edwards mitral valve prosthesis. Initially Corynebacterium hofmanni was isolated from blood culture. Later, while the patient was receiving antibacterial chemotherapy, Candida albicans was also isolated and she was treated with 5-fluorocytosine. A cure was effected without the need for further valve replacement.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • English TA, Ross JK. Surgical aspects of bacterial endocarditis. Br Med J. 1972 Dec 9;4(5840):598–602. [PMC free article] [PubMed]
  • Record CO, Skinner JM, Sleight P, Speller DC. Candida endocarditis treated with 5-fluorocytosine. Br Med J. 1971 Jan 30;1(5743):262–264. [PMC free article] [PubMed]
  • Warner JF, McGehee RF, Duma RJ, Shadomy S, Utz JP. 5-fluorocytosine in human candidiasis. Antimicrob Agents Chemother (Bethesda) 1970;10:473–475. [PubMed]

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