Search tips
Search criteria 


Logo of brheartjLink to Publisher's site
Br Heart J. 1980 September; 44(3): 284–289.
PMCID: PMC482399

Serial measurements of left ventricular dimensions by echocardiography. Assessment of week-to-week, inter- and intraobserver variability in normal subjects and patients with valvular heart disease.


The week-to-week, inter- and intraobserver variation in left ventricular echocardiographic measurements has been studied in 10 normal male volunteers and in five patients with stable valvular disease. A two-way analysis of variance showed no statistically significant variation either from week to week or between observers. Furthermore the within observer variation was minimal. Calculation of the coefficient of variation allowed confidence limits to be applied to each of the six ventricular measurements, thus providing ranges of variation in follow-up studies using M-mode echocardiography.

Full text

Full text is available as a scanned copy of the original print version. Get a printable copy (PDF file) of the complete article (1.1M), or click on a page image below to browse page by page. Links to PubMed are also available for Selected References.

Images in this article

Click on the image to see a larger version.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Sahn DJ, DeMaria A, Kisslo J, Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978 Dec;58(6):1072–1083. [PubMed]
  • Henry WL, Clark CE, Epstein SE. Asymmetric septal hypertrophy. Echocardiographic identification of the pathognomonic anatomic abnormality of IHSS. Circulation. 1973 Feb;47(2):225–233. [PubMed]
  • Feigenbaum H, Popp RL, Chip JN, Haine CL. Left ventricular wall thickness measured by ultrasound. Arch Intern Med. 1968 May;121(5):391–395. [PubMed]
  • Chapelle M, Mensch B. Etude des variations du diamètre ventriculaire gauche chez l'homme par échocardiographie transthoracique. Arch Mal Coeur Vaiss. 1969 Nov;62(11):1505–1517. [PubMed]
  • Troy BL, Pombo J, Rackley CE. Measurement of left ventricular wall thickness and mass by echocardiography. Circulation. 1972 Mar;45(3):602–611. [PubMed]
  • Redwood DR, Henry WL, Epstein SE. Evaluation of the ability of echocardiography to measure acute alterations in left ventricular volume. Circulation. 1974 Nov;50(5):901–904. [PubMed]
  • Burggraf GW, Parker JO. Left ventricular volume changes after amyl nitrite and nitroglycerin in man as measured by ultrasound. Circulation. 1974 Jan;49(1):136–143. [PubMed]
  • Hardarson T, Wright KE. Effect of sublingual nitroglycerin on cardiac performance in patients with coronary artery disease and non-dyskinetic left ventricular contraction. Br Heart J. 1976 Dec;38(12):1272–1277. [PMC free article] [PubMed]
  • Awan NA, Miller RR, Mason DT. Comparison of effects of nitroprusside and prazosin on left ventricular function and the peripheral circulation in chronic refractory congestive heart failure. Circulation. 1978 Jan;57(1):152–159. [PubMed]
  • Frishman W, Smithen C, Befler B, Kligfield P, Killip T. Noninvasive assessment of clinical response to oral propranolol therapy. Am J Cardiol. 1975 May;35(5):635–644. [PubMed]
  • Pombo JF, Troy BL, Russell RO., Jr Left ventricular volumes and ejection fraction by echocardiography. Circulation. 1971 Apr;43(4):480–490. [PubMed]
  • Stefadouros MA, Canedo MI. Reproducibility of echocardiographic estimates of left ventricular dimensions. Br Heart J. 1977 Apr;39(4):390–398. [PMC free article] [PubMed]
  • Martin MA, Fieller NR. Echocardiography in cardiovascular drug assessment. Br Heart J. 1979 May;41(5):536–543. [PMC free article] [PubMed]
  • Gibson DG, Brown D. Measurement of instantaneous left ventricular dimension and filling rate in man, using echocardiography. Br Heart J. 1973 Nov;35(11):1141–1149. [PMC free article] [PubMed]

Articles from British Heart Journal are provided here courtesy of BMJ Publishing Group