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Br Heart J. 1980 September; 44(3): 280–283.
PMCID: PMC482398

Systolic and diastolic time intervals in young diabetics.

Abstract

Systolic and diastolic time intervals were used to examine left ventricular performance in 22 young diabetic men (mean age 25 years) with no apparent clinical heart disease. Pre-ejection period index (PEPI), left ventricular ejection time index (LVETI), electromechanical systole index (QS2I), PEP to LVET ratio, the a wave percentage amplitude of the apexcardiogram (a/H5 ratio), the rapid filling wave (RFW), and the A2O interval were obtained in the conventional manner in 22 diabetics and 22 healthy men. The heart rate, diastolic pressure, PEP/LVET ratio, a/H per cent ratio, and A2O interval were significantly increased and LVET decreased in the diabetic group. QS2I, PEPI, and RFW did not differ from that in the normal group. Twenty-three per cent of patients had an abnormal systolic time interval, 54 percent an abnormal diastolic time interval, and 23 per cent had both abnormal intervals. Though these studies provide no difinite evidence of a cause, the abnormalities found may reflect a subclinical diabetic cardiopathy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • Ledet T, Neubauer B, Christensen NJ, Lundbaek K. Diabetic cardiopathy. Diabetologia. 1979 Apr;16(4):207–209. [PubMed]
  • Zoneraich S, Zoneraich O, Rhee JJ, Liao C, Patel MM. Electrocardiographic findings in diabetic patients without clinical evidence of heart involvement. N Y State J Med. 1977 Jul;77(8):1254–1258. [PubMed]
  • Lewis RP, Rittogers SE, Froester WF, Boudoulas H. A critical review of the systolic time intervals. Circulation. 1977 Aug;56(2):146–158. [PubMed]
  • Manolas J, Rutishauser W. Relation between apex cardiographic and internal indices of left ventricular relaxation in man. Br Heart J. 1977 Dec;39(12):1324–1332. [PMC free article] [PubMed]
  • Weissler AM, Harris WS, Schoenfeld CD. Bedside technics for the evaluation of ventricular function in man. Am J Cardiol. 1969 Apr;23(4):577–583. [PubMed]
  • Ahmed SS, Jaferi GA, Narang RM, Regan TJ. Preclinical abnormality of left ventricular function in diabetes mellitus. Am Heart J. 1975 Feb;89(2):153–158. [PubMed]
  • Rubler S, Sajadi RM, Araoye MA, Holford FD. Noninvasive estimation of myocardial performance in patients with diabetes. Effect of alcohol administration. Diabetes. 1978 Feb;27(2):127–134. [PubMed]
  • Ahmed SS, Levinson GE, Schwartz CJ, Ettinger PO. Systolic time intervals as measures of the contractile state of the left ventricular myocardium in man. Circulation. 1972 Sep;46(3):559–571. [PubMed]
  • Voigt GC, Friesinger GC. The use of apexcardiography in the assessment of left ventricular diastolic pressure. Circulation. 1970 Jun;41(6):1015–1024. [PubMed]
  • Gibson TC, Madry R, Grossman W, McLaurin LP, Craige E. The A wave of the apexcardiogram and left ventricular diastolic stiffness. Circulation. 1974 Mar;49(3):441–446. [PubMed]
  • Sanderson JE, Brown DJ, Rivellese A, Kohner E. Diabetic cardiomyopathy? An echocardiographic study of young diabetics. Br Med J. 1978 Feb 18;1(6110):404–407. [PMC free article] [PubMed]
  • Zoneraich S, Zoneraich O, Rhee JJ. Left ventricular performance in diabetic patients without clinical heart disease. Evaluation by systolic time intervals and echocardiography. Chest. 1977 Dec;72(6):748–751. [PubMed]
  • Jarrett J. Diabetes and the heart: coronary heart disease. Clin Endocrinol Metab. 1977 Jul;6(2):389–402. [PubMed]
  • Regan TJ, Lyons MM, Ahmed SS, Levinson GE, Oldewurtel HA, Ahmad MR, Haider B. Evidence for cardiomyopathy in familial diabetes mellitus. J Clin Invest. 1977 Oct;60(4):884–899. [PMC free article] [PubMed]
  • Gundersen HJ, Neubauer B. A long-term diabetic autonomic nervous abnormality. Reduced variations in resting heart rate measured by a simple and sensitive method. Diabetologia. 1977 Apr;13(2):137–140. [PubMed]

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