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Br Heart J. 1984 February; 51(2): 175–178.
PMCID: PMC481479

Transvenous high energy shock for ablating atrioventricular conduction in man. Observations on the histological effects.


Transvenous ablation of atrioventricular conduction by high energy shock through a pacing wire has been used as a method of controlling the ventricular response to rapid atrial arrhythmias. A patient in whom this technique successfully controlled refractory tachycardia was admitted with severe left ventricular impairment five months after the procedure and died. The heart was examined at necropsy. There was no sign of endocardial damage in the region of the atrioventricular node-His bundle. Histological sections failed to show any scarring, inflammation, or infiltration in the region of the atrioventricular node. On the contrary, there was no evidence of any surviving atrioventricular nodal tissue. The mechanism of this effect is not known. The lack of endocardial or myocardial damage further confirms the safety of this new method of controlling tachycardia.

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Selected References

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  • Camm J, Ward DE, Spurrell RA, Rees GM. Cryothermal mapping and cryoablation in the treatment of refractory cardiac arrhythmias. Circulation. 1980 Jul;62(1):67–74. [PubMed]
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