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J Clin Pathol. 1975 April; 28(4): 332–336.
PMCID: PMC475701

A new method for the assay of factor XI in plasma and the preparation and use of a new artificial substrate

Abstract

An improved method for the one-stage assay of factor XI in plasma has been proposed; it is reproducible and compares well with an old, established method.

A short investigation into the preparation and use of artificially prepared factor XI-deficient plasma has been carried out: this substrate can be used as an alternative to the congenitally deficient substrate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
  • EGEBERG O. Assay of antihemophilic A, B and C factors by one-stage cephalin systems. Scand J Clin Lab Invest. 1961;13:140–152. [PubMed]
  • Nossel HL, Niemetz J, Mibashan RS, Schulze WG. The measurement of factor XI (Plasma thromboplastin antecedent). Diagnosis and therapy of the congenital deficiency state. Br J Haematol. 1966 Mar;12(2):133–144. [PubMed]
  • RAPAPORT SI, SCHIFFMAN S, PATCH MJ, WARE AG. A simple, specific one-stage assay for plasma thromboplastin antecedent activity. J Lab Clin Med. 1961 May;57:771–780. [PubMed]
  • RATNOFF OD, CRUM JD. ACTIVATION OF HAGEMAN FACTOR BY SOLUTIONS OF ELLAGIC ACID. J Lab Clin Med. 1964 Mar;63:359–377. [PubMed]

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