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Logo of jclinpathJournal of Clinical PathologyCurrent TOCInstructions for authors
J Clin Pathol. Feb 1970; 23(1): 68–76.
PMCID: PMC474420
An assessment of the Coulter counter model S
P. H. Pinkerton, I. Spence, J. C. Ogilvie, W. A. Ronald, Patricia Marchant, and P. K. Ray
Department of Laboratory Haematology, University of Toronto Clinic, Sunnybrook Hospital, Toronto, Canada
Institute of Applied Statistics, University of Toronto, Toronto, Canada
An assessment of the Coulter model S automatic blood counter has been carried out. The standard deviations for the haemoglobin concentration, haematocrit, red cell count, and white cell count are, respectively, ± 0·15 g/100 ml, ± 0·45%, ± 0·04 m/c mm, and ± 0·47 thous/c mm. These results are clearly more accurate than careful manual estimates, performed for comparison on the same samples. Details of the comparisons are presented. A comparison is also made with routine daily estimations.
`Carryover' from one sample to the next was found to be about 2%, and tests in the ranges likely to be found in practice showed good linearity for the haemoglobin estimation, haematocrit, red cell count, and white cell count. A brief account of instrument failures is given.
The performance of the Coulter model S compares well with that of other automated equipment for which detailed evaluations are available.
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