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Braz J Microbiol. 2011 Oct-Dec; 42(4): 1265–1268.
Published online 2011 December 1. doi:  10.1590/S1517-83822011000400003
PMCID: PMC3768718

Comparison of teicoplanin disk diffusion and broth microdilution methods against clinical isolates of Staphylococcus aureus and S. epidermidis


The CLSI M100-S19 document has recommended the disuse of vancomycin disks for staphylococci and informed that studies on the action of teicoplanin in disk-diffusion testing should be performed. We describe the comparison of two methods, disk diffusion and broth microdilution, for determining teicoplanin susceptibility in clinical isolates of staphylococci. Overall results showed an aggregation rate of 96.8%; Staphylococcus aureus showed total agreement while S. epidermidis showed 93.8% of agreement. According to these local results, disk diffusion can still be employed to teicoplanin susceptibility determination for staphylococci in our institution.

Keywords: Teicoplanin, susceptibility tests, S. aureus, S. epidermidis

Articles from Brazilian Journal of Microbiology are provided here courtesy of Elsevier