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Appl Microbiol. 1972 September; 24(3): 384–388.
PMCID: PMC376528

Hydrodynamic Focusing and Electronic Cell-Sizing Techniques


The technique of hydrodynamic focusing, used to improve the resolution of the Coulter counter for the sizing of bacteria, was examined. Latex particles of 0.26 μm3 to 6.7 μm3 volume were used to examine the characteristics of the system with and without hydrodynamic focusing. The system then was evaluated for sizing mixed bacterial populations as well as single populations. Possible applications are also discussed.

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