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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
 
From:
Clin Lymphoma Myeloma Leuk. Author manuscript; available in PMC 2013 July 29.
Published in final edited form as:
Clin Lymphoma Myeloma Leuk. 2010 June; 10(3): 205–210.
doi: 10.3816/CLML.2010.n.032

Table 5

Side Effects Reported According to Each Hypomethylating Agent

Toxicity, nHypomethylating Agent
AzacitidineDecitabine
Grades 1–2Grades 3–4Grades 1–2Grades 3–4
Extramedullary Toxicitiesa
 Fatigue1291
 Bone aches111
 Liver dysfunction221
 Skin rashes121
 Nausea and vomiting1131
 Diarrhea2111
 Other123
Myelosuppression-Related Toxicitiesa
 Fever of unknown origin112
Documented Bacterial Infections
 Sepsis alone414
 Minor infections14
Pneumonias With or Without Other Infections1212
Fungal Infections
 Confirmed2
 Suspected1
Bleeding2142
HospitalizationbNA26NA35
aN = 41 patients.
bN = 187 courses.

Abbreviation: NA = not applicable