PMCCPMCCPMCC

Search tips
Search criteria 

Advanced


 
Formats
Article sections
Authors
Related links
Logo of aghpsycbiomed central web sitesearch.manuscript submission.see also annals of general psychiatry journal in pmc.registration.reference to the article.journal front page.
 
Ann Gen Hosp Psychiatry. 2004; 3: 3.
Published online 2004 February 13. doi:  10.1186/1475-2832-3-3
PMCID: PMC368443
Copyright © 2004 Ito et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the article's original URL.
Gender difference in QTc prolongation of people with mental disorders
Hiroto Ito,corresponding author1 Toshiaki Kono,2 Shigenobu Ishida,3 and Hisao Maeda3
1National Institute of Public Health, 2-3-6 Minami, Wako, Saitama 351-0197, Japan
2Department of Psychiatry, Division of Neuroscience, Graduate School of Medicine, The University of Tokyo, Japan
3Department of Neuropsychiatry, Kurume University School of Medicine, Japan
corresponding authorCorresponding author.
Hiroto Ito: ito/at/niph.go.jp; Toshiaki Kono: tkono-tky/at/umin.ac.jp; Shigenobu Ishida: ishidas/at/med.kurume-u.ac.jp; Hisao Maeda: maehisa/at/med.kurume-u.ac.jp
Received June 20, 2003; Accepted February 13, 2004.
Small right arrow pointing to: This article has been cited by other articles in PMC.
Abstract
Background
We examined gender difference in QTc interval distribution and its related factors in people with mental disorders.
Methods
We retrospectively reviewed medical charts of patients discharged from a university psychiatric unit between November 1997 and December 2000. Subjects were 328 patients (145 males and 183 females) taking psychotropics at their admission. We examined patient characteristics, medical history, diagnosis, and medication before admission.
Results
Mean QTc interval was 0.408 (SD = 0.036). QTc intervals in females were significantly longer than those in males. QTc of females without comorbidity was significantly longer than that of males.
Conclusion
The influence of gender difference on QTc prolongation in people with mental disorders merits further research.
Articles from Annals of General Hospital Psychiatry are provided here courtesy of
BioMed Central