To examine the feasibility of continuous glucose monitoring (CGM) use in very young children with type 1 diabetes (T1D).
Research Design and Methods
23 children less than 4 years of age with T1D were provided with a FreeStyle Navigator® (n=21) or a Paradigm® (n=2) CGM device. At baseline, mean age was 3.0 ± 0.8 years, mean HbA1c was 8.0 ± 0.8 %, 10 were using an insulin pump and 13 were on multiple daily injections. CGM use was evaluated over a 6-month period.
Three children dropped out of the study before the end of 6 months. Among the 20 children who completed 6 months of follow-up, CGM use in month 6 was ≥6 days/week in 9 (45%), 4-<6 days/week in 2 (10%), and <4 days/week in 9 (45%). Skin reactions were minimal. Although there was no detectable change in mean HbA1c between baseline and 6 months (7.9% and 8.0%, respectively), there was a high degree of parental satisfaction with CGM as measured on the CGM Satisfaction Scale questionnaire. A high percentage of glucose values were in the hyperglycemic range and biochemical hypoglycemia was infrequent.
More than 40% of very young children were able to safely use CGM on a near daily basis after 6 months. CGM demonstrated frequent hyperglycemic excursions, with a large variability in glucose readings. Although improvement in glycemic control was not detected in the group as a whole, parental satisfaction with CGM was high.
Keywords: Continuous Glucose Monitoring, Young Children, T1D