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Mol Cell Biol. Feb 1991; 11(2): 1180–1183.
PMCID: PMC359807
Nuclear and cytoplasmic location of the FER tyrosine kinase.
Q L Hao, D K Ferris, G White, N Heisterkamp, and J Groffen
Department of Pathology, Childrens Hospital, Los Angeles 90027.
The location of the FER protein within the cell was investigated by using subcellular fractionation and immunofluorescence. FER was found in the cytoplasm and in the nucleus, where it was associated with the chromatin fraction. Its ubiquitous expression and its subcellular location indicate that it may be involved in key regulatory processes.
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