Funding for the project is provided by the National Institutes of Health: NIH-NIDDK R01-DK58369 from 1999 to 2005 and NIH-NIDDK U01 DK072146 from 2005 to the present, and the General Clinical Research Center Program for Research Resources (RR00069).
Key individuals who have actively participated in the PALF studies include (by site) the following: Current sites, principal investigators, and coordinators: Robert H. Squires, MD, Beverly Bernard, CRNP, Kathryn Bukauskas, RN, CCRC (Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, PA); Michael R. Narkewicz, MD, Michelle Hite, MA, CCRC (Children’s Hospital Colorado, Aurora, CO); Kathleen M. Loomes, MD, David Piccoli, MD, Elizabeth B. Rand, MD, Deborah Kawchak, MS, RD (Children’s Hospital of Philadelphia, Philadelphia, PA); Estella M. Alonso, MD, Lisa Sorenson, PhD, Susan Kelly, RN, BSN, Katie Neighbors, MPH, CCRC (Children’s Memorial Hospital, Chicago, IL); Rene Romero, MD, Saul Karpen, MD, PhD, Sundari Sekar, MBBS, DGO, Gail Schwartz, RN, BSN (Emory University, Atlanta, GA); Vicky Ng, MD, Ann Fu, Clinical Research Coordinator (Hospital for Sick Children, Toronto, Canada); Girish C. Subbarao, MD, Ann Klipsch, RN (Indiana University Riley Hospital, Indianapolis, IN); Philip J. Rosenthal, MD, Shannon Fleck, Clinical Research Coordinator (University of California San Francisco, San Francisco, CA); Mike A. Leonis, MD, PhD, John Bucuvalas, MD, Andre Hawkins, MA, CCRP (University of Cincinnati, Cincinnati, OH); Norberto Rodriguez Baez, MD, Shirley Montanye, RN, Clinical Research Coordinator (University of Texas Southwestern, Dallas, TX); Simon P. Horslen, MD, Melissa Young, Clinical Research Coordinator (University of Washington, Seattle, WA); David A. Rudnick, MD, PhD, Sandra Guelker, Clinical Research Coordinator (Washington University, St Louis, MO).
Previous sites, principal investigators, and coordinators: Saul J. Karpen, MD, PhD, Alejandro De La Torre, Clinical Research Coordinator (Baylor College of Medicine, Houston, TX); Dominic Dell Olio, MD, Deirdre Kelly, MD, Carla Lloyd, Clinical Research Coordinator (Birmingham Children’s Hospital, Birmingham, UK); Steven J. Lobritto, MD, Sumerah Bakhsh, MPH, Clinical Research Coordinator (Columbia University, New York, NY); Maureen Jonas, MD, Scott A. Elifoson, MD, Roshan Raza, MBBS (Harvard Medical School, Boston, MA); Kathleen B. Schwarz, MD, Wikrom W. Karnsakul, MD, Mary Kay Alford, RN, MSN, CPNP (Johns Hopkins University, Baltimore, MD); Anil Dhawan, MD, Emer Fitzpatrick, MD (King’s College Hospital, London, UK); Nanda N. Kerkar, MD, Brandy Haydel, CCRC, Sreevidya Narayanappa, Clinical Research Coordinator (Mt Sinai School of Medicine, New York, NY); M. James Lopez, MD, PhD, Victoria Shieck, RN, BSN (University of Michigan, Ann Arbor, MI).
The authors are also grateful for support from the National Institutes of Health (Patricia R. Robuck, PhD, MPH, Director Clinical Trials Program, and Edward Doo, MD, Director Liver Diseases Research Program, Division of Digestive Diseases and Nutrition-National Institute of Diabetes and Digestive and Kidney Diseases) and for assistance from members of the Data Coordinating Center at the University of Pittsburgh (directed by Steven H. Belle, PhD, MScHyg).
We are especially indebted to and thank Laura James, MD (Department of Pediatrics, University of Arkansas for Medical Sciences) for her thoughtful review of this manuscript.