Fungal Toxicity of Phosfon D and Its Reversion by Lipids

Antimicrob Agents Chemother. 1978 April; 13(4): 699–700.

PMCID: PMC352313

Fungal Toxicity of Phosfon D and Its Reversion by Lipids

G. L. Vannini, G. Dall'olio, and A. Donini

¹Institute of Botany, University of Ferrara, I-44100 Ferrara, Italy

Abstract

The growth retardant Phosfon D inhibits the growth of some yeasts and human pathogenic filamentous fungi. The toxic effects of the compound on the dermatophyte Microsporum cookei were completely reversed by adding ergosterol and oleic acid to the medium. The significance of these findings is discussed.

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