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Logo of nihpaAbout Author manuscriptsSubmit a manuscriptHHS Public Access; Author Manuscript; Accepted for publication in peer reviewed journal;
 
From:
Am J Psychiatry. Author manuscript; available in PMC 2013 August 1.
Published in final edited form as:
Am J Psychiatry. 2012 August 1; 169(8): 851–859.
doi: 10.1176/appi.ajp.2012.11101546

Table 2

Demographic and clinical characteristics for acutely depressed (aMDD), recovered depressed (rMDD), and their matched control groups(C-aMDD, C-rMDD).

CharacteristicsAcutely Depressed (aMDD, N=8)aMDD Controls (C-aMDD, N=8)Recovered Depressed (rMDD, N=15)rMDD Controls (C-rMDD, N=15)Statistics
Age, years, mean (SD)36.3 (13.8)37.3 (15.5)32.5 (10.6)31.8 (11.0)F3,42= 0.51 p=0.68
Gender (male), N (%)3 (37.5)3 (37.5)3 (20)3 (20)X23 =1.7, p=0.65
Race, N (%)
 Caucasian5(62.5)8(100)12(80)8(53.3)X23 =7.9, p=0.048
 Non-Caucasian3(37.5)-3 (20)7(46.7)
CES-D29.1 (5.8)2.3 (3.3)4.7 (5.9)3.3 (3.6)F3,39 =53.7, p=0.000
BDI score, mean (SD)20.4 (4.2)2.0 (2.3)2.7 (4.8)1.1 (1.7)F3,37 =28.4, p=0.000
NEO-PI-R score, mean (SD)
 Neuroticism111.5 (17.5)-76.4 (23.1)-F1,19 =11.1, p=0.03
 Extraversion89 (19.3)-108.9 (19.2)-F1,19 =4.6, p=0.045
 Openness to experience125.8 (15.7)-130.8 (18.7)-F1,19 = 0.3, p=0.57
 Agreeableness116.8 (14.5)-132.1 (19.7)-F1,19 =3.0, p=0.1
 Concientiousness91.5 (9.1)-123.9 (26.2)-F1,19 =8.6, p=0.09
DAS score, mean (SD)163.4 (49.9)-113.7 (27.4)-F1,21 =9.7, p=0.005
CTQ total score, mean (SD)4.9 (3.3)-2.1 (2.3)-F1,21 =5.7, p=0.03
 Emotional abuse1.4 (1.1)-0.6 (0.7)-F1,20 =3.6, p=0.07
 Physical abuse0.6 (1.2)-0.4 (0.9)-F1,20 =0.2, p=0.67
 Sexual abuse0.8 (1.4)-0.2 (0.8)-F1,20 =1.5, p=0.26
 Emotional neglect1.4 (0.9)-0.9 (1.1)-F1,20 =1.4, p=0.27
 Physical neglect0.8 (1.2)-0.1 (0.3)-F1,20 =4.5, 0.047
STAI-State score, mean (SD)53.6 (3.2)23 (4.2) N=228.3 (7.4)24.2 (7.4) N=6F3,21 =28.0, p=0.000
STAI-Trait score, mean (SD)56.4 (6.4) N=524 (5.7) N=232.5 (8.8) N=1224.8 (4.8) N=6F3,21 =19.4, p=0.000
Age of onset, years, mean (SD)17.7 (4.9)-18 (4.6)-F1,20 =0.02, p=0.90
Lifetime number of depressive episodes, mean (SD)4.8 (3.8)a-4.9 (6.2)-F1,17 =0.01, p=0.97
Number of weeks depressed, mean (SD)28 (17.9)a-50.6 (87.6)-F1,16 =0.21, p=0.65
Number of euthymic months, mean (SD)--26.3 (25.6)-
Past psychotropic medication use
 SSRIs5-12-
 SNRIs2-1-
 Mood stabilizers0-1-
 Antipsychotics0-1-
 Anxiolytics3-1-
 Medication naive3-2-
Lifetime smoking history, N (%)2 (25)0 (0)8 (53.3)1 (6.6)X26 =15.1 p=0.02
CO level on scan day, ppm, mean (SD)2 (1.6)1.4 (1.9)1 (1.4)2.2 (2.1)F3,42 =1.3, p=0.28
aSubjects with episodic illness were included.