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Published online 2012 August 14. doi: 10.1186/1743-422X-9-161

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Phylogenetic trees of ancestral NCLDV genes involved in DNA replication. (A). DNA polymerase, the original ML tree. (B). DNA polymerase, constrained tree, monophyly of NCLDV, baculoviruses and herpesviruses enforced. (C). Primase-helicase. (D). FLAP endonuclease. Branches with bootstrap support less than 50 were collapsed. For each sequence, the species name abbreviation and the gene identification numbers are indicated. Species abbreviations: Arath, Arabidopsis thaliana; Desps, Desulfotalea psychrophila LSv54; Dessa, Desulfovibrio salexigens DSM 2638; Emihu, Emiliania huxleyi virus 86; Enccu, Encephalitozoon cuniculi GB-M1; Entdi, Entamoeba dispar SAW760; Lacre, Lactobacillus reuteri DSM 20016; Leibr, Leishmania braziliensis MHOM/BR/75/M2904; Macmu, Macaca mulatta; Phatr, Phaeodactylum tricornutum CCAP 1055/1; Tetth, Tetrahymena thermophila; Triva, Trichomonas vaginalis G3; Bf, Firmicutes; Bp, Proteobacteria; E8, Stramenopiles; E9, Viridiplantae; Ea, Amoebozoa; Ec, Alveolata; Ek, Euglenozoa; El, Opisthokonta; Ew, Parabasalidea; q2, Coccolithovirus.

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