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Logo of bmcphBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Public Health
BMC Public Health. 2012; 12: 318.
Published online Apr 30, 2012. doi:  10.1186/1471-2458-12-318
PMCID: PMC3488479
Does treatment adherence correlates with health related quality of life? findings from a cross sectional study
Fahad Saleem,corresponding author1 Mohamed Azmi Hassali,2 Asrul Akmal Shafie,2 George A Awad,3 Muhammad Atif,4 Noman ul Haq,1 Hisham Aljadhey,5 and Maryam Farooqui6
1Department of Pharmacy, University of Baluchistan, Quetta, Pakistan/PhD candidate, Discipline of Social & Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Penang, Malaysia
2Discipline of Social & Administrative Pharmacy, School of Pharmaceutical Sciences, Universiti Sains Malaysia, Minden, 11800, Penang, Malaysia
3Humber River Regional Hospital, 2175 Keele Street, Suite 243A, Toronto, Ontario, M6M 3Z4, Canada
4School of Pharmacy, Allianze University, College of Medical Sciences, Kepala Batas, 13200, Penang, Malaysia
5College of Pharmacy, King Saud University, Riyadh, 11451, Saudi Arabia
6Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Bertam, 13200, Penang, Malaysia
corresponding authorCorresponding author.
Fahad Saleem: fahaduob/at/; Mohamed Azmi Hassali: azmihassali/at/; Asrul Akmal Shafie: aakmal/at/; George A Awad: gawad/at/; Muhammad Atif: pharmacist_atif/at/; Noman ul Haq: nomanhaq79/at/; Hisham Aljadhey: haljadhey/at/; Maryam Farooqui: maryamfarooqui.uitm/at/
Received December 31, 2011; Accepted April 30, 2012.
Although medication adherence and health-related quality of life (HRQoL) are two different outcome measures, it is believed that adherence to medication leads to an improvement in overall HRQoL. The study aimed to evaluate the association between medication adherence and HRQoL.
A questionnaire-based cross-sectional study design was undertaken with hypertension patients attending public hospitals in Quetta city, Pakistan. HRQoL was measured by Euroqol EQ-5D. Medication adherence was assessed by the Drug Attitude Inventory. Descriptive statistics was used to tabulate demographic and disease-related information. Spearmans correlation was used to assess the association between the study variables. All analysis was performed using SPSS 17.0.
Among 385 study patients, the mean age (SD) was 39.02 (6.59), with 68.8% of males dominating the entire cohort. The mean (SD) duration of hypertension was 3.010.939years. Forty percent (n=154) had a bachelors degree level of education with 34.8% (n=134) working in the private sector. A negative and weak correlation (0.77) between medication adherence and EQ-5D was reported. In addition, a negative weak correlation (0.120) was observed among medication adherence and EQ-VAS.
Correlations among the study variables were negligible and negative. Hence, there is no apparent relationship between the variables.
Keywords: Medication adherence, Health related quality of life, Association, Hypertension
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