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Logo of annsurginresBioMed CentralBiomed Central Web Sitesearchsubmit a manuscriptregisterthis articleAnnals of Surgical Innovation and Research
 
From:
Published online 2012 September 4. doi: 10.1186/1750-1164-6-8

Table 1

Summary of study characteristics

Study, YearStudy designEnd pointDefinition of ColonisationDefinition of CRBSI
Bijma[7], 1999
Prospective longitudinal cohort study
Impact of intervention plan on CVC colonisation and infection incidence
Growth of >15 cfu from the removed tip
Clinical signs of BSI in the absence of another focus of infection + both peripheral blood culture and catheter tip culture test positive for same organism
Dimick[8], 2001
Prospective cohort study
Estimated increase in resource use associated with CRBSI of critically ill surgical patients after adjusting for severity of illness.
Growth of >15 cfu from the removed tip
Both peripheral blood culture and catheter tip culture test positive for same organism within 48 hours of each other
Dimick[9], 2003
Prospective cohort study
Multipurpose CVC vs TPN CVC; risk factors, incidence and pathogens of CRBSI
Growth of >15 cfu from the removed tip
Both peripheral blood culture and catheter tip culture test positive for same organism within 48 hours of each other
Sandoe[10], 2003
Prospective cohort study
Impact of extended routine perioperative antibiotic prophylaxis on incidence of CVC colonisation and infection
Growth of >15 cfu from the removed tip
Positive same-organism peripheral blood culture and catheter tip culture when catheter in situ
Pawar[11], 2004
Prospective cohort study
Incidence, risk factors, outcome, and pathogens of CVC-BSI
Growth of <15 cfu from the removed tip
Clinical signs of BSI and both peripheral blood culture and catheter tip culture test positive for same organism OR resolution of fever after the removal of a CVC suspected of infection.
Le Guillou[12], 2011
Retrospective cohort study
Proportion of surgical-site infections (SSIs) with possible attribution to CRBSI, risk factors associated with SSI after CRBSI.
Growth of >103 cfu/mL, and without clinical evidence of infection
BSI occurring 48 hours before/after catheter removal and positive culture with the same micro- organism of either (i) quantitative CVC culture >103 cfu/mL; (ii) positive culture from pus from insertion site; (iii) quantitative blood culture ratio CVC blood sample: peripheral blood sample >5; or (iv) differential time to positivity of blood cultures: CVC blood sample culture positive >2 hours before peripheral blood culture (blood samples drawn at the same time).
Gunst[13], 2011Retrospective cohort studyPICC VS CVC risk factors and incidence of CRBSIGrowth of >15 cfu from the removed tipBoth peripheral blood culture and catheter tip culture test positive for same organism

Abbreviations:CVC: Central venous catheter; PICC: Peripherally inserted central catheter; cfu: Colony forming units; TPN: Total parenteral nutrition; BSI: Bloodstream infection.