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Ann Lab Med. Nov 2012; 32(6): 442–444.
Published online Oct 17, 2012. doi:  10.3343/alm.2012.32.6.442
PMCID: PMC3486941
The First Korean Case Report of Anti-Gerbich
You La Jeon, M.D.,1,4 Tae Sung Park, M.D.,2 Sun Young Cho, M.D.,2 Seung Hwan Oh, M.D.,3 Myeong Hee Kim, M.D.,4 So Young Kang, M.D.,4 and Woo-In Lee, M.D.corresponding author4
1Department of Medicine, Kyung Hee University Graduate School Seoul, Korea.
2Department of Laboratory Medicine, Kyung Hee University School of Medicine Seoul, Korea.
3Department of Laboratory Medicine, Inje University College of Medicine, Busan, Korea.
4Department of Laboratory Medicine, Kyung Hee University Hospital at Gangdong, Seoul, Korea.
corresponding authorCorresponding author.
Corresponding author: Woo-In Lee. Department of Laboratory Medicine, Kyung Hee University Hospital at Gangdong, 892 Dongnam-ro, Gangdong-gu, Seoul 134-727, Korea. Tel: +82-2-440-7190, Fax: +82-2-440-7195, wileemd/at/khu.ac.kr
Received April 26, 2012; Revised June 5, 2012; Accepted July 24, 2012.
Abstract
In this study, we report the first Korean case of an anti-Gerbich (Ge) alloantibody to a high-incidence antigen that belongs to the Ge blood group system. The alloantibody was detected in a middle-aged Korean woman who did not have a history of transfusion. Her blood type was B+, and findings from the antibody screening test revealed 1+ reactivity in all panels except the autocontrol. The cross-matching test showed incompatible results with all 5 packed red blood cells. Additional blood type antigen and antibody tests confirmed the anti-Ge alloantibody. While rare, cases of hemolytic transfusion reaction or hemolytic disease in newborns due to anti-Ge have been recently reported in the literature. Therefore, additional further studies on alloantibodies to high-incidence antigens, including anti-Ge, are necessary in the future.
Keywords: Ge, Blood group antigens, Transfusion
Articles from Annals of Laboratory Medicine are provided here courtesy of
Korean Society for Laboratory Medicine