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Ann Lab Med. 2012 November; 32(6): 426–428.
Published online 2012 October 17. doi:  10.3343/alm.2012.32.6.426
PMCID: PMC3486937
Copyright © The Korean Society for Laboratory Medicine.
Antifungal Susceptibility to Amphotericin B, Fluconazole, Voriconazole, and Flucytosine in Candida Bloodstream Isolates from 15 Tertiary Hospitals in Korea
Sook-In Jung, M.D.,1 Jong Hee Shin, M.D.,corresponding author2 Hyun-Jung Choi, M.D.,2 Min-Young Ju, M.S.,2 Soo-Hyun Kim, M.D.,2 Wee Gyo Lee, M.D.,3 Yeon-Joon Park, M.D.,4 Kyungwon Lee, M.D.,5 and Korean Study Group for Candidemia
1Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea.
2Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea.
3Department of Laboratory Medicine, Ajou University College of Medicine, Suwon, Korea.
4Department of Laboratory Medicine, The Catholic University of Korea College of Medicine, Seoul, Korea.
5Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea.
corresponding authorCorresponding author.
Corresponding author: Jong Hee Shin. Department of Laboratory Medicine, Chonnam National University Medical School, 671 Jebong-ro, Dong-gu, Gwangju 501-757, Korea. Tel: +82-62-220-5342, Fax: +82-62-224-2518, shinjh/at/chonnam.ac.kr
Received June 7, 2012; Revised June 28, 2012; Accepted September 10, 2012.
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4 antifungal drugs remain low among Candida bloodstream isolates in Korea.
Keywords: Candida, Amphotericin B, Flucytosine, Fluconazole, Voriconazole
Articles from Annals of Laboratory Medicine are provided here courtesy of
Korean Society for Laboratory Medicine