PMCCPMCCPMCC

Search tips
Search criteria 

Advanced

 
Logo of bmcmidmBioMed Centralsearchsubmit a manuscriptregisterthis articleBMC Medical Informatics and Decision Making
 
BMC Med Inform Decis Mak. 2012; 12: 98.
Published online 2012 September 4. doi:  10.1186/1472-6947-12-98
PMCID: PMC3473237
Supporting meningitis diagnosis amongst infants and children through the use of fuzzy cognitive mapping
Vijay K Mago,corresponding author1 Ravinder Mehta,2 Ryan Woolrych,3 and Elpiniki I Papageorgiou4
1The Modelling of Complex Social Systems (MoCSSy) Program, The IRMACS Centre, Simon Fraser University, Burnaby, Canada
2, Mehta Child Care Centre, Punjab, Sangrur, India
3Gerontology Research Centre, Simon Fraser University, Burnaby, Canada
4Department of Informatics and Computer Technology, Technological Educational Institute of Lamia, Lamia, Greece
corresponding authorCorresponding author.
Vijay K Mago: vmago/at/sfu.ca; Ravinder Mehta: rmehtarmehta/at/yahoo.co.in; Ryan Woolrych: rwoolryc/at/sfu.ca; Elpiniki I Papageorgiou: epapageorgiou/at/teilam.gr
Received November 7, 2011; Accepted August 27, 2012.
Abstract
Background
Meningitis is characterized by an inflammation of the meninges, or the membranes surrounding the brain and spinal cord. Early diagnosis and treatment is crucial for a positive outcome, yet identifying meningitis is a complex process involving an array of signs and symptoms and multiple causal factors which require novel solutions to support clinical decision-making. In this work, we explore the potential of fuzzy cognitive map to assist in the modeling of meningitis, as a support tool for physicians in the accurate diagnosis and treatment of the condition.
Methods
Fuzzy cognitive mapping (FCM) is a method for analysing and depicting human perception of a given system. FCM facilitates the development of a conceptual model which is not limited by exact values and measurements and thus is well suited to representing relatively unstructured knowledge and associations expressed in imprecise terms. A team of doctors (physicians), comprising four paediatricians, was formed to define the multifarious signs and symptoms associated with meningitis and to identify risk factors integral to its causality, as indicators used by clinicians to identify the presence or absence of meningitis in patients. The FCM model, consisting of 20 concept nodes, has been designed by the team of paediatricians in collaborative dialogue with the research team.
Results
The paediatricians were supplied with a form containing various input parameters to be completed at the time of diagnosing meningitis among infants and children. The paediatricians provided information on a total of 56 patient cases amongst children whose age ranged from 2 months to 7 years. The physicians’ decision to diagnose meningitis was available for each individual case which was used as the outcome measure for evaluating the model. The FCM was trained using 40 cases with an accuracy of 95%, and later 16 test cases were used to analyze the accuracy and reliability of the model. The system produced the results with sensitivity of 83.3% and specificity of 80%.
Conclusions
This work suggests that the application and development of a knowledge based system, using the formalization of FCMs for understanding the symptoms and causes of meningitis in children and infants, can provide a reliable front-end decision-making tool to better assist physicians.
Articles from BMC Medical Informatics and Decision Making are provided here courtesy of
BioMed Central