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Logo of jbcThe Journal of Biological Chemistry
 
J Biol Chem. 2012 October 5; 287(41): 34494.
PMCID: PMC3464554

PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA.

VOLUME 285 (2010) PAGES 8054–8060

PAGE 8057:

The authors have become aware of mistakes in Fig. 2, where blots were erroneously misused because some of them were used in a previous article (Lethio, L., Jemth, A.-S., Collins, R., Loseva, O., Johansson, A., Markova, N., Hammarström, M., Flores, A., Holmberg-Schiavone, L., Weigelt, J., Helleday, T., Schüler, H., and Karlberg, T. (2009) J. Med. Chem. 52, 3108–3111). To correct this mistake, all panels in Fig 2A have been replaced. In Fig 2B, panels showing inhibition of PARP3 by Ku0058948, DR2313, PJ34, and 3ABA have been replaced. The corrected Fig. 2 and legend are shown below, and the authors apologize for any confusion this mistake may have caused. This correction does not influence the validity of the results and the conclusions of the original article.

FIGURE 2.
Inhibition of PARP-3 and PARP-1 activity by various inhibitors. A, shown is the time course of the dose-dependent inactivation of auto-ADP-ribosylation of PARP-3 and PARP-1, respectively, by KU0058948. This is a repeat of the experiment published earlier ...

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