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AIDS Res Treat. 2012; 2012: 352753.
Published online Sep 26, 2012. doi:  10.1155/2012/352753
PMCID: PMC3463904
CD4 Count Pattern and Demographic Distribution of Treatment-Naïve HIV Patients in Lagos, Nigeria
Akinsegun Akinbami, 1 * Adedoyin Dosunmu, 1 Adewumi Adediran, 2 Sarah Ajibola, 3 Olajumoke Oshinaike, 4 Kikelomo Wright, 5 and Olanrewaju Arogundade 1
1Department of Haematology and Blood Transfusion, College of Medicine, Lagos State University, Ikeja, PMB 21266, Lagos, Nigeria
2Department of Haematology and Blood Transfusion, Faculty of Clinical Sciences, College of Medicine, University of Lagos, PMB 12003, Idiaraba, Lagos, Nigeria
3Department of Haematology and Blood Transfusion, Lagos University Teaching Hospital, PMB 12003, Idiaraba, Lagos, Nigeria
4Department of Medicine, College of Medicine, Lagos State University, Ikeja, PMB 1266, Lagos, Nigeria
5Department of Community Health and Primary Health Care, College of Medicine, Lagos State University, Ikeja, PMB 21266, Lagos, Nigeria
*Akinsegun Akinbami: ajoke_clinic/at/yahoo.co.uk
Academic Editor: Giuseppe Ippolito
Received January 12, 2012; Revised August 24, 2012; Accepted August 26, 2012.
Abstract
Background. CD4 count measures the degree of immunosuppression in HIV-positive patients. It is also used in deciding when to commence therapy, in staging the disease, and in determining treatment failure. Using the CD4 count, this study aimed at determining the percentage of HIV-positives who require antiretroviral therapy at enrollment in an HIV treatment and care centre. Methods. The Baseline CD4 count, age and gender of 4,042 HAART-naïve patients, who registered between December 2006 and June 2010, at Lagos State University Teaching Hospital, Ikeja, were retrospectively studied. Data were analyzed using SPSS version 16.0 (Statistical Package for Social Sciences, Inc., Chicago, Ill). Results. Patients consisted of 2507 (62%) female and 1535 (38%) males. The mean age of males was 37.73 ± 9.48 years and that of females 35.01 ± 9.34 years. Overall, the mean CD4 count was of 298.76 ± 246.93  cells/mm3. The mean CD4 count of males was 268.05 ± 230.44  cells/mm3 and that of females 317.55 ± 254.72 cells/mm3. A total of 72.3% males, 64.3% females and 67.4% overall registered patients had CD4 count <350 cells/mm3, while only 15.1% males , 20.3% females, and 18.3% overall registered patients had CD4 count >500 cells/mm3 at registration. Conclusion. Females account for more than half of registered patients in HIV clinic and have a relatively higher CD4 count than males. About three-quarter of HIV positives require antiretroviral therapy at registration.
Articles from AIDS Research and Treatment are provided here courtesy of
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