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Logo of bmcbiophysBioMed CentralBiomed Central Web Sitesearchsubmit a manuscriptregisterthis articleBMC BiophysicsJournal Front Page
BMC Biophys. 2012; 5: 9.
Published online 2012 May 14. doi:  10.1186/2046-1682-5-9
PMCID: PMC3463482

DelPhi: a comprehensive suite for DelPhi software and associated resources



Accurate modeling of electrostatic potential and corresponding energies becomes increasingly important for understanding properties of biological macromolecules and their complexes. However, this is not an easy task due to the irregular shape of biological entities and the presence of water and mobile ions.


Here we report a comprehensive suite for the well-known Poisson-Boltzmann solver, DelPhi, enriched with additional features to facilitate DelPhi usage. The suite allows for easy download of both DelPhi executable files and source code along with a makefile for local installations. The users can obtain the DelPhi manual and parameter files required for the corresponding investigation. Non-experienced researchers can download examples containing all necessary data to carry out DelPhi runs on a set of selected examples illustrating various DelPhi features and demonstrating DelPhi’s accuracy against analytical solutions.


DelPhi suite offers not only the DelPhi executable and sources files, examples and parameter files, but also provides links to third party developed resources either utilizing DelPhi or providing plugins for DelPhi. In addition, the users and developers are offered a forum to share ideas, resolve issues, report bugs and seek help with respect to the DelPhi package. The resource is available free of charge for academic users from URL:

Keywords: DelPhi, Poisson-Boltzmann equation, Implicit solvation model, Electrostatics, Biological macromolecules, Software

Articles from BMC Biophysics are provided here courtesy of BioMed Central