Maximum patients i.e.; 60% were in the age group of 51-60 years. Fifty-five percent were male, 40% were housewives, and 95% were married, 75% were Hindu, 35% were belonging to upper middle class of the society and 60% nonvegetarian.
Effect of therapies: Twenty patients were selected in the present study, 10 patients in each group. The efficacy of each therapy was adjudging on varied parameters and the results were derived after execution of statistical methodology. The data regarding effect of therapies on systolic and diastolic blood pressure of individual patients of both groups is provided in .
Effect on systolic and diastolic blood pressure (mmHg) of group A and group B
In group A, 10 patients had completed the treatment with highly significant relief in: Shiroruka- Headache (84.61%), Bhrama- Giddiness (75%), Alpanidra- Insomnia (69.56%), Daurbalya- Weakness (56.67%), Klama- Fatigue (51.85%), Buddhisammoha- lack concentration and decision power (78.26%), Krodhaprachuryata-Mental irritability (78.57%), Malavarodha- Constipation (74.07%), Smrutihrasha- Forgetfulness (84%), Aruchi- Anorexia (91.66%), in Hriddravatva-Palpitation (66.67%), Aayaasjanyaswasakashtata– Dyspnea (52.94%), Arati- Uneasiness (57.14%), Santapa -Feeling of tension (54.54%), Akshiraaga -Redness of eyes (54.54%), and significant relief Urahashoola -Chest pain (80%), Tamodarshana -Flashing before eyes (33.33%), Pada Shotha-Pedal edema (71.42%) .
Effect on chief and associated complaints of group A
In group B, 10 patients had completed therapy with highly significant improvement on: Shiroruka (85%), Bhrama (70.96%), Aayaasjanyaswasakashtata (68.75%%), Alpanidra (75%), Urahashoola (75%), Daurbalya (54.54%), Klama (51.51%), Tamodarshana (76.92%), Krodhaprachuryata (57.14%), Malavarodha (58.33%), Smrutihrasha (69.56%), Arati (52.38), Aruchi (77.77%), Buddhi Samoha (69.23%), significant relief in Hriddravatva (40%), Santapa (40%), Pada-Shotha (60%), Akshiraaga (50%) . Relief in high blood pressure was observed in 8.91% and 8.44% in systolic and diastolic blood pressure, respectively, treated with Shankhapushpyadi Ghana Vati whereas by Sarpagandhadi Ghana Vati, better relief was obtained i.e.; 12.00% and 11.02% relief in systolic and diastolic blood pressure, respectively . Both drugs, showed highly significant relief in systolic as well as diastolic blood pressure. Significant relief in pulse pressure were observed in both Group A (8.36%) and Group B (14.74%), while mean arterial blood pressure showed highly significant result in both Group A (8.41%), and Group B (12.43%).
Effect on chief and associated complaints of group B
Effect of therapies on systolic and diastolic blood pressure before and after treatment
On hematological investigations, hemoglobin of therapeutic groups was insignificantly increased by Shankhapushpyadi Ghana Vati (4.88%) and insignificant decreased by Sarpagandhadi Ghana Vati (1.68%) and erythrocyte sedimentation rate (ESR) was also reduced by Shankhapushpyadi Ghana Vati (41.6%) and improved by Sarpagandhadi Ghana Vati (30.02%).
Changes in lipid profile, in group A, Vati serum cholesterol (14.93%) and in group B, serum cholesterol (10.31%) were found insignificant.
On renal profile, blood urea (13.23%) were decreased in group-A, and in group-B, (3.96%). The result was statistically insignificant.
On biochemical parameters, postprandial urine sugar (0.20%) was increased and fasting blood sugar (4.64%) was reduced in group A whereas in group B, fasting blood sugar (1.64%) and postprandial blood sugar (3.1%) were decreased and the result was statistically insignificant.
Analyzing the overall effect of therapy, in sign and symptoms of disease, 30% patients were markedly improved, 60% were moderately improved, 10% were mild improved and none patient observed in no response category in Group A, whereas in group B, 20% patients were markedly improved, 80% moderately improved .
Estimation of overall response on chief and associated complains of each Group
Overall effect of therapy, in systolic and diastolic blood pressure, 40% and 70% patients were markedly improved, 40% and 10% were moderately improved, 20% and 20% were mild improved respectively, in Group A, whereas in Group B, 60% and 50% patients were markedly improved, 40% and 30% moderately improved, respectively [Tables ,].
Estimation of overall response on systolic blood pressure of each group
Estimation of overall response on diastolic blood pressure of each group