Search tips
Search criteria 


Logo of jargspringer.comThis journalToc AlertsSubmit OnlineOpen Choice
J Assist Reprod Genet. 2003 April; 20(4): 157–159.
PMCID: PMC3455634

Short Communication: Does Preejaculatory Penile Secretion Originating from Cowper's Gland Contain Sperm?


Purpose: To determine if spermatozoa are present in the preejaculatory penile secretion, originating from Cowper's gland.

Methods:Design: Prospective clinical and laboratory study. Setting: Andrology and Sex Counseling Unit, Department of Obstetrics and Gynecology, Academic Teaching Hospital. Patients: Five patients referred for premature ejaculation, three for excessive fluid secreted during foreplay and four normal healthy volunteers. Intervention: Glass slide smears of preejaculatory Cowper's gland secretion obtained during foreplay from at least two different occasions, and semen samples after masturbation. Main Outcome Measures: Microscopic examination of air-dried smears, and routine semen analyses.

Results: None of the preejaculatory samples contained sperm. All the patients had sperm in routine sperm analyses.

Conclusions: Preejaculatory fluid secreted at the tip of the urethra from Cowper's gland during sexual stimulation did not contain sperm and therefore cannot be responsible for pregnancies during coitus interruptus.

Keywords: Cowper's gland, ejaculation, sperm

Full Text

The Full Text of this article is available as a PDF (212K).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.
1. Masters WH, Johnson VE, editors. Human Sexual Response. Boston: Little, Brown Company; 1966. p. 293.
2. Masters WH, Johnson VE, Kolodny RC, editors. Human Sexuality. Boston: Little, Brown and Company; 1982. p. 51.
3. Francoeur RT, editor. Becoming a Sexual Person. New York: Wiley; 1982. p. 285.
4. McCary JL, editor. McCary's Human Sexuality. 3rd edn. New York: Van Nostrand; 1978. p. 51.
5. Sandler J, Myerson M, Kinder BN, editors. Human Sexuality–Current Perspectives. Tampa, FL: Mariner Publishing; 1980. p. 60.
6. Hatcher RH, Stewart GK, Guest F, editors. Contraception Technology. New York: Livingston Publishers; 1976.

Articles from Journal of Assisted Reproduction and Genetics are provided here courtesy of Springer Science+Business Media, LLC