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J Assist Reprod Genet. 2003 April; 20(4): 157–159.
PMCID: PMC3455634

Short Communication: Does Preejaculatory Penile Secretion Originating from Cowper's Gland Contain Sperm?

Abstract

Purpose: To determine if spermatozoa are present in the preejaculatory penile secretion, originating from Cowper's gland.

Methods:Design: Prospective clinical and laboratory study. Setting: Andrology and Sex Counseling Unit, Department of Obstetrics and Gynecology, Academic Teaching Hospital. Patients: Five patients referred for premature ejaculation, three for excessive fluid secreted during foreplay and four normal healthy volunteers. Intervention: Glass slide smears of preejaculatory Cowper's gland secretion obtained during foreplay from at least two different occasions, and semen samples after masturbation. Main Outcome Measures: Microscopic examination of air-dried smears, and routine semen analyses.

Results: None of the preejaculatory samples contained sperm. All the patients had sperm in routine sperm analyses.

Conclusions: Preejaculatory fluid secreted at the tip of the urethra from Cowper's gland during sexual stimulation did not contain sperm and therefore cannot be responsible for pregnancies during coitus interruptus.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.
1. Masters WH, Johnson VE, editors. Human Sexual Response. Boston: Little, Brown Company; 1966. p. 293.
2. Masters WH, Johnson VE, Kolodny RC, editors. Human Sexuality. Boston: Little, Brown and Company; 1982. p. 51.
3. Francoeur RT, editor. Becoming a Sexual Person. New York: Wiley; 1982. p. 285.
4. McCary JL, editor. McCary's Human Sexuality. 3rd edn. New York: Van Nostrand; 1978. p. 51.
5. Sandler J, Myerson M, Kinder BN, editors. Human Sexuality–Current Perspectives. Tampa, FL: Mariner Publishing; 1980. p. 60.
6. Hatcher RH, Stewart GK, Guest F, editors. Contraception Technology. New York: Livingston Publishers; 1976.

Articles from Journal of Assisted Reproduction and Genetics are provided here courtesy of Springer Science+Business Media, LLC